This page shows the details of all 1st author publications of our graduates who were conferred their MSc/ PhD degree in 2019.

S/N Main Supervisor Name Student Name Degree Department Thesis Title First author publication details
1 Adam Claridge-Chang (Dr) Tayfun Tumkaya Doctor of Philosophy Physiology INNATE AND LEARNED VALENCE: LESSONS FROM THE DROSOPHILA OLFACTORY SYSTEM 1. Neuroscience and Biobehavioral Reviews, 95, 361-382,  A systematic review and meta-analysis of Drosophila short-term-memory genetics: robust reproducibility, but little independent replication, 12/2018, https://doi.org/10.1016/j.neubiorev.2018.07.016
2 Alan Prem Kumar (Dr) Lui Kit Leng Sarah Master of Science Pharmacology INVESTIGATING THE ROLE OF USP26 AND SHP2 IN THE REGULATION OF THE SMURF2-SMAD7-MEDIATED DOWNREGULATION OF THE TGF-ß PATHWAY 1. EMBO Reports, 18, 511-657, USP26 regulates TGF -ß signaling by deubiquitinating and stabilizing SMAD7, 04/2017, DOI: 10.15252/embr.201643270
3 Alan Prem Kumar (Dr) Shreya Kar Doctor of Philosophy Pharmacology THE ROLE OF ANNEXIN A1 IN THE DYNAMICS OF MACROPHAGE POLARIZATION IN THE BREAST TUMOR MICROENVIRONMENT 1. Cancer Treatment Reviews, Volume 62, Pages 29–38, Triple negative breast cancer in Asia: An insider’s view, 01/2018, DOI:  10.1016/j.ctrv.2017.10.014
4 Alonso, Sylvie (A/Prof) Lee Pei Xuan Doctor of Philosophy Microbiology and Immunology INVESTIGATING THE ROLE OF DENGUE-SPECIFIC IMMUNITY IN PROTECTION AND DISEASE USING SYMPTOMATIC MOUSE MODELS 1. PLoS Negl Trop Dis, 10(6), e0004805, Relative contribution of dengue IgG antibodies acquired during gestation or breastfeeding in mediating dengue disease enhancement and protection in type I interferon receptor-deficient mice., 06/2016, DOI: https://doi.org/10.1371/journal.pntd.0004805
5 Baeg Gyeong Hun (Dr) Sharon Tan Wui Sing Doctor of Philosophy Anatomy REDOX HOMEOSTASIS IN THE DROSOPHILA TESTIS STEM CELL SELF-RENEWAL AND MAINTENANCE 1. Redox Biology, 15, 125-134, Small Maf functions in the maintenance of germline stem cells in the Drosophila testis, 12/2017, https://doi.org/10.1016/j.redox.2017.12.002

2. Stem Cell Reports, 9, 342-354, Redox Homeostasis Plays Important Roles in the Maintenance of the Drosophila Testis Germline Stem Cells, 06/2017, https://doi.org/10.1016/j.stemcr.2017.05.034

6 Bay Boon Huat (Prof) Lim Jia Pei Doctor of Philosophy Anatomy BIOLOGICAL INSIGHTS INTO Y-BOX BINDING PROTEIN-1 (YB-1) MEDIATED BREAST CANCER METASTASIS 1. BMC Cancer, Mar 16;17(1), 201, YBX1 gene silencing inhibits migratory and invasive potential via CORO1C in breast cancer in vitro., 03/2017, DOI: 10.1186/s12885-017-3187-7.

2. Exp Mol Pathol., Dec;105(3), 364-370, A-kinase anchor protein 12 (AKAP12) inhibits cell migration in breast cancer, 12/2018, DOI: 10.1016/j.yexmp.2018.10.010.

3. Food Chem Toxicol, Nov;109(Pt 1), 771-779, Potential adverse effects of engineered nanomaterials commonly used in food on the miRNome., 11/2017, DOI: 10.1016/j.fct.2017.07.030.

4. Int J Oncol., Dec;53(6), 2579-2589, Y-box binding protein-1 and STAT3 independently regulate ATP-binding cassette transporters in the chemoresistance of gastric cancer cells., 12/2018, DOI: 10.3892/ijo.2018.4557.

7 Chang, Matthew Wook (A/Prof) Pham Hoang Long Doctor of Philosophy Biochemistry PROGRAMMING SELF-DIRECTED EVOLUTION IN BACTERIA 1. Current Opinion in Biotechnology, 48, 85-93,  Applying the design-build-test paradigm in microbiome engineering, 12/2017, https://doi.org/10.1016/j.copbio.2017.03.021

2. Nature Communications, 411, Engineering a riboswitch-based genetic platform for the self-directed evolution of acid-tolerant phenotypes, 09/2017,  https://doi.org/10.1038/s41467-017-00511-w

8 Chen Leilei (Dr) Han Jian Doctor of Philosophy Cancer Science Institute (CSI) REGULATION OF CANCER TRANSCRIPTOME DIVERSITY BY ADAR-INTERACTING PARTNER DAP3 AND HYPOXIA 1. Scientific reports, 7, 4108, Hypoxia is a key driver of alternative splicing in human breast cancer cells, 06/2017,  https://doi.org/10.1038/s41598-017-04333-0
9 Chester Lee Drum (Dr) Masurkar Nihar Doctor of Philosophy Medicine THERMOSTABLE EXOSHELLS AS TOOLS FOR RECOMBINANT PROTEIN EXPRESSION AND IN VIVO DELIVERY 1. Nature Communications, 13, 1442, Thermostable exoshells fold and stabilize recombinant proteins, 11/2017, DOI: 10.1038/s41467-017-01585-2
10 Chng Wee Joo (Prof) Chooi Jing Yuan Doctor of Philosophy Medicine IDENTIFICATION OF FUNCTIONAL PROTEINS INTERACTING WITH MMSET IN MULTIPLE MYELOMA 1. Leukemia, 29, 753-757, Cbfb deficiency results in differentiation blocks and stem/progenitor cell expansion in hematopoiesis., 03/2015, DOI: 10.1038/leu.2014.316
11 Chong Yap Seng (Prof) Chia Airu Doctor of Philosophy Obstetrics & Gynaecology MATERNAL DIETARY PATTERNS, METABOLITE PROFILING, AND INFANT BIRTH OUTCOMES 1. Adv Nutr, Maternal Dietary Patterns and Birth Outcomes: A Systematic Review and Meta-Analysis, 04/2019, In Press DOI: 10.1093/advances/nmy123

2. Am J Clin Nutr, 104 (5), 1416-1423, A vegetable, fruit, and white rice dietary pattern during pregnancy is associated with a lower risk of preterm birth and larger birth size in a multi-ethnic Asian cohort: The GUSTO study., 10/2016,DOI:  10.3945/ajcn.116.133892

3. Am J Clin Nutr, 105 (4), 1010-1011,Reply to V Ansu and K He, 04/2017, DOI:  10.3945/ajcn.116.149690

4. Am J Clin Nutr, 107 (1), 71-79, Adherence to a healthy eating index for pregnant women is associated with lower neonatal adiposity in a multiethnic Asian cohort: The GUSTO Study, 01/2018, DOI: 10.1093/ajcn/nqx003

5. J Nutr, 145(6), 1303-1310, Maternal Protein Intake during Pregnancy Is Not Associated with Offspring Birth Weight in a Multiethnic Asian Population, 05/2015, DOI:  10.3945/jn.114.205948

6. Sci Rep, 8(1), 730, The relationship of dietary fish intake to diabetic retinopathy and retinal vascular caliber in patients with type 2 diabetes, 01/2018, DOI: 10.1038/s41598-017-18930-6

12 Chu Jang Hann (A/Prof) Shefali Banerjee Doctor of Philosophy Microbiology and Immunology THE ROLE(S) OF ENDOTHELIAL MICRORNAS IN DENGUE VIRUS PATHOGENESIS AND ENDOTHELIAL PERMEABILITY 1. Future virology, 10, 1101-1108, Potential prognostic markers for predicting onset of dengue hemorrhagic fever, 09/2015, DOI: 08/09/2015
13 Dario Campana (Prof) Png Yi Tian Doctor of Philosophy Paediatrics DEVELOPMENT OF NOVEL T-CELL BASED THERAPIES FOR LYMPHOID MALIGNANCIES 1. Blood Advances, 1, 2348-2360, Blockade of CD7 expression in T cells for effective chimeric antigen receptor targeting of T-cell malignancies, 11/2017, https://doi.org/10.1182/bloodadvances.2017009928
14 Deron Raymond Herr (Dr) Malavika Srikanth Doctor of Philosophy Pharmacology ROLE OF PLA2-DERIVED BIOACTIVE LIPIDS IN NEUROINFLAMMATION 1. European Journal of Pharmacology, 841, 49-56, Lysophosphatidic acid and its receptor LPA1 mediate carrageenan induced inflammatory pain in mice., 12/2018, DOI: 10.1016/j.ejphar.2018.10.005.

2. Neuromolecular Medicine, 20, 504-514, Metabolism of Docosahexaenoic Acid (DHA) Induces Pyroptosis in BV-2 Microglial Cells., 12/2018, DOI: 10.1007/s12017-018-8511-0

15 Deron Raymond Herr (Dr) Wang Wei Doctor of Philosophy Pharmacology ROLES OF SPHINGOSINE 1-PHOSPHATE RECEPTOR 2 (S1P2) IN NEURAL AND CANCER CELLS: IMPLICATION FOR PREVENTION OF CISPLATIN-INDUCED PERIPHERAL NEUROPATHY 1. Cellular Signalling, 34, 66-75, Mechanisms of sphingosine 1-phosphate receptor signalling in cancer, 03/2017, DOI:  10.1016/j.cellsig.2017.03.002

2. The FASEB journal,  Sphingosine 1–phosphate signaling induces SNAI2 expression to promote cell invasion in breast cancer cells, 03/2019, DOI: 10.1096/fj.201801635R

16 Dheen, Shaikali Thameem (A/Prof) Seshadri Ramya Doctor of Philosophy Anatomy ANALYSIS OF EPIGENETIC MECHANISMS IN NEURAL STEM CELLS OF MOUSE EMBRYOS FROM DIABETIC PREGNANCY 1. Frontiers in Molecular Neuroscience, 10, 237, Maternal Diabetes Alters Expression of MicroRNAs that Regulate Genes Critical for Neural Tube Development, 07/2017,
17 Ellen Birgitte Lane (Prof) Giorgiana Ribeiro Salgado Doctor of Philosophy Pathology BROADENING THE APPLICATION OF CULTURED HUMAN KERATINOCYTE GRAFTING 1.Differentiation, 98, 14-24, Human reconstructed skin xenografts on mice to model skin physiology, 09/2017, DOI: 10.1016/j.diff.2017.09.004
18 Fu Xin-Yuan (Prof) Mu Tianhao Doctor of Philosophy Biochemistry SINGLE-CELL RNA-SEQ DECIPHERS ENDODERMAL ORIGIN AND LIVER DEVELOPMENT BY TRACING FOXA2 LINEAGE 1. Thoracic Cancer, 8, 606-612, Effects of FSTL1 on the proliferation and motility of breast cancer cells and vascular endothelial cells, 07/2017, doi: 10.1111/1759-7714.12491
19 H. Phillip Koeffler (Prof) Han, Lin Doctor of Philosophy Medicine ROLE OF SWI/SNF COMPONENT ARID1A IN HEMATOPOIETIC DEVELOPMENT 1. Leukemia, Chromatin remodeling mediated by ARID1A is indispensable for normal hematopoiesis in mice, 03/2019, DOI: 10.1038/s41375-019-0438-4
20 Hu Qidong (Dr) Charannya Sozheesvari Subhramanyam Doctor of Philosophy Anatomy ROLE OF PIWI/PIRNA IN REGULATING MICROGLIAL ACTIVATION AND NEURONAL DIFFERENTIATION 1. Current Medicinal Chemistry, 24, 1983-1997, Non-coding RNA in brain development and disorder, 02/2017, DOI: 10.2174/0929867324666170124151436
21 Jan Gruber (Dr) Tesfahun Dessale Admasu Doctor of Philosophy Biochemistry DRUG SYNERGY, TARGETING EVOLUTIONARY CONSERVED LONGEVITY AND AGING NETWORKS TO EXTEND HEALTHY LIFESPAN 1. Developmental Cell, 47, 1-13, Drug synergy slows aging and inproves healthspan through IGF and SREBP lipid signaling, 09/2018, DOI: 10.1016/j.devcel.2018.09.001

2. Nature Scientific data, 5, 231-239, Lipid profile of C. elegans strains administered pro-longevity drugs and srug combinations, 10/2018, DOI: 10.1038/sdata.2018.231

22 Jan Gruber (Dr) Yee Zhuangli Doctor of Philosophy Biochemistry TESTING DAMAGE ACCUMULATION THEORIES OF AGEING IN CAENORHABDITIS ELEGANS, MITOCHONDRIAL DNA DELETION AND PROTEIN AGGREGATION AS DETERMINANTS OF LIFESPAN 1. Aging Cell, 17 (5), e12814, Clonal expansion of mitochondrial DNA deletions is a private mechanism of aging in long-lived animals, 07/2018, DOI: 10.1111/acel.12814
23 Lai Poh San (A/Prof) Yim Onn Siong Doctor of Philosophy Paediatrics THE RELATIONSHIP OF TELOMERE LENGTH WITH BEHAVIOURAL PHENOTYPES IN HUMANS 1. Proc Natl Acad Sci USA, 113(10), 2780-2785, Delay discounting, genetic sensitivity, and leukocyte telomere length., 03/2016, DOI: 10.1073/pnas.1514351113
24 Larbi Anis (Dr) Anteneh Mehari Tizazu Doctor of Philosophy Microbiology and Immunology METFORMIN DECREASES AGING AND DIABETES ASSOCIATED CHRONIC INFLAMMATION AND HAS AN IMMUNOMODULATORY ROLE 1. Frontiers in Physiology, 10, 572, Metformin Monotherapy Downregulates Diabetes-Associated Inflammatory Status and Impacts on Mortality, 05/2019, https://doi.org/10.3389/fphys.2019.00572
25 Lim Yoon Pin (Dr) Alisha Francis Ramos Doctor of Philosophy Biochemistry PI3K/AKT MEDIATED PHOSPHORYLATION OF USF-1 ENHANCES ITS TRANSCRIPTIONAL ACTIVATION OF WBP2 ONCOGENE IN BREAST CANCER CELLS 1. Faseb, 32, 20, Phosphorylation of E-box binding USF-1 by PI3K/AKT enhances its transcriptional activation of the WBP2 oncogene in breast cancer cells, 08/2018, In Press, December 2018
26 Lim Yoon Pin (Dr) Hossein Tabatabaeian Doctor of Philosophy Biochemistry WBP2 – A NOVEL TARGET OF HIPPO-INDUCED MIRNAS AND A REGULATOR OF THE MICROPROCESSOR COMPLEX IN BREAST CANCER 1. Gene, 549, 1-6, Investigation of sensitivity, specificity and accuracy of Tetra primer ARMS PCR method in comparison with conventional ARMS PCR, based on sequencing technique outcomes in IVS-II-I genotyping of beta thalassemia patients, 10/2014,  https://doi.org/10.1016/j.gene.2014.05.071

2. Gene, 531, 39-43, Assessment of HER-2 gene overexpression in Isfahan province breast cancer patients using real time RT-PCR and immunohistochemistry, 11/2013,  https://doi.org/10.1016/j.gene.2013.08.040

3. Journal of cancer research and therapeutics, 15, 108-114, miR-146a is deregulated in gastric cancer, 01/2019, DOI: 10.4103/jcrt.JCRT_855_17

4. The Breast, 42, 157-163, ErbB4 receptor polymorphism 2368A> C and risk of breast cancer, 12/2018, https://doi.org/10.1016/j.breast.2018.10.002

27 Ling Shuo-Chien (Dr) Jin Wenhao Doctor of Philosophy Physiology PREDICTIVE MODELS TO DISCOVER NOVEL RNA-BINDING PROTEINS 1. Molecular Cell, 64, 282-293, SONAR discovers RNA-binding proteins from analysis of large-scale protein-protein interactomes, 10/2016, https://doi.org/10.1016/j.molcel.2016.09.003
28 Ling Shuo-Chien (Dr) Wang Jia Doctor of Philosophy Physiology FUNCTIONS AND MECHANISMS UNDERLYING THE ESSENTIAL ROLES OF TDP-43, AN ALS/FTD PATHOLOGICAL SIGNATURE PROTEIN IN OLIGODENDROCYTES 1. PNAS, 115, E10941-E10950, Cell-autonomous requirement of TDP-43, an ALS/FTD signature protein, for oligodendrocyte survival and myelination, 11/2018, DOI: 1809821115
29 Melissa Jane Fullwood (Dr) Cao Fan Doctor of Philosophy Cancer Science Institute (CSI) UNDERSTANDING CHROMATIN INTERACTIONS FROM 1-DIMENSIONAL EPIGENETIC MARKS AND DNA SEQUENCES 1.Scientific Reports, 7, 2186, Super-Enhancers and Broad H3K4me3 Domains Form Complex Gene Regulatory Circuits Involving Chromatin Interactions, 05/2017, DOI:  10.1038/s41598-017-02257-3
30 Ng Huck Hui (Prof) Sidika Tapsin Doctor of Philosophy Biochemistry GENOME-WIDE IDENTIFICATION OF RNA SENSORS IN PROKARYOTES AND EUKARYOTES 1. Nature communications, 9, 1289, Genome-wide identification of natural RNA aptamers in prokaryotes and eukaryotes, 03/2018, DOI: 10.1038/s41467-018-03675-1
31 Nicholas Iain James Paton (Prof) Annanya Shetty Doctor of Philosophy Medicine ANALYSIS OF MYCOBACTERIAL CELL ENVELOPE STRESS AND DISCOVERY OF A NOVEL MMPL3 INHIBITOR 1. Frontiers in Microbiology, 9, 2960, Novel acetamide indirectly targets mycobacterial transporter MmpL3 by proton motive force disruption, 12/2018, DOI: 10.3389/fmicb.2018.01898

2. Frontiers in Microbiology, 9, 1898, Mycobacterial Cell Wall Synthesis Inhibitors Cause Lethal ATP Burst, 08/2018,DOI: 10.3389/fmicb.2018.02960

32 Nicholas Iain James Paton (Prof) Dereje Abate Negatu Doctor of Philosophy Medicine FRAGMENT SCREEN IDENTIFIES MICROBIOTA METABOLITE THAT TARGETS TRYPTOPHAN BIOSYNTHESIS IN MYCOBACTERIUM TUBERCULOSIS 1. Antimicrobial Agents and Chemotherapy, 62, 8, Whole-cell screen of fragment library identifies gut microbiota metabolite indole propionic acid as antitubercular, 12/2017, DOI: 10.1128/AAC.01571-17

2. mBio, 10, 15, Gut microbiota metabolite indole propionic acid targets tryptophan biosynthesis in Mycobacterium tuberculosis, 03/2019, DOI:  10.1128/mBio.02781-18

33 Nicholas Iain James Paton (Prof) Wassihun Wedajo Aragaw Doctor of Philosophy Medicine DHFR INHIBITOR TRIAZA-COUMARIN IS A F420 REDOX-ACTIVATED DUAL MECHANISM ANTITUBERCULAR 1. European Journal of Medicinal Chemistry, 144, 262-276, 1,3,5-triazaspiro[5.5]undeca-2,4-dienes as selective Mycobacterium tuberculosis dihydrofolate reductase inhibitors with potent whole cell activity, 12/2017, doi.org/10.1016/j.ejmech.2017.12.017
34 Nicholas Robert John Gascoigne (Prof) Mukul Prasad Doctor of Philosophy Microbiology and Immunology ROLE OF THEMIS IN TYPE 2 DIABETES 1. Journal of Natural Science, Biology, and Medicine, 6(1), 80-84, Evaluation of DNA Damage in Type 2 Diabetes Mellitus Patients with and without Peripheral Neuropathy: A Study in South Indian Population., 01/2015, DOI: 10.4103/0976-9668.149096
35 Paul A MacAry (A/Prof) Loghman Salimzadeh Doctor of Philosophy Microbiology and Immunology B CELL IMMUNITY IN HBV INFECTION 1. Journal of Clinical Investigation, 128, 4573, PD-1 blockade partially recovers dysfunctional virus–specific B cells in chronic hepatitis B infection, 08/2018, https://doi.org/10.1172/JCI121957
36 Paul Anantharajah Tambyah (Prof) Mandakhalikar Kedar Diwakar Doctor of Philosophy Medicine PREVENTION OF INFECTION IN UROLOGY PATIENTS THROUGH THE USE OF NOVEL DEVICES 1. BMC Infectious Diseases, 18:370, 9,  Restriction of in vivo infection by antifouling coating on urinary catheter with controllable and sustained silver release: a proof of concept study, 08/2018, DOI: 10.1186/s12879-018-3296-1

2. Current Treatment Options in Infectious Diseases, 8:1, 18, New Technologies for Prevention of Catheter Associated Urinary Tract Infection, 03/2016, DOI: 10.1007/s40506-016-0069-5

3. Scientific Reports, 8, 9, Extraction and quantification of biofilm bacteria: Method optimized for urinary catheters, 05/2018, DOI:  10.1038/s41598-018-26342-3

37 Renia Laurent Claude (Prof) Chang Zi Wei Doctor of Philosophy Microbiology and Immunology ROLE OF IMMUNE SYSTEM IN THE CLEARANCE OF PLASMODIUM DURING ARTESUNATE THERAPY 1. Antimicrobial Agents and Chemotherapy, 60, 6859-6866, Ex Vivo Maturation Assay for Testing Antimalarial Sensitivity of Rodent Malaria Parasites, 11/2016, DOI: 10.1128/AAC.01292-16

2. Cellular Microbiology., 19, e12763, Adaptive immunity is essential in preventing recrudescence of Plasmodium yoelii malaria parasites after artesunate treatment, 11/2017, DOI: 10.1111/cmi.12763

38 Reshma Taneja (A/Prof) Akshay V Bhat Doctor of Philosophy Physiology ROLE OF G9A LYSINE METHYLTRANSFERASE IN ALVEOLAR RHABDOMYOSARCOMA 1. Antioxidants & Redox Signaling, 29, 1273-1292, Stressing the (Epi)Genome: Dealing with Reactive Oxygen Species in Cancer, 08/2018, https://doi.org/10.1089/ars.2017.7158
39 Reshma Taneja (A/Prof) Shruti Srinivasan Doctor of Philosophy Physiology ROLE OF SUMOYLATION IN THE REGULATION OF G9A FUNCTION 1. Cell Death and Disease, 02/2019, Accepted, https://www-nature-com.libproxy1.nus.edu.sg/cddis/
40 Robert Charles Robinson (A/Prof) Clement Pierre Marcel Scipion Doctor of Philosophy Biochemistry DESIGN OF PEPTIDES TO PREVENT ACTIN POLYMERIZATION 1. PNAS, 115, 10345-10350, Structural evidence for the roles of divalent cations in actin polymerization and activation of ATP hydrolysis, 10/2018, DOI: 10.1073/pnas.1806394115
41 Shek Pei-Chi, Lynette (Prof) Chew Jian Ming Lamony Doctor of Philosophy Paediatrics EVALUATION OF THE IMMUNOMODULATORY EFFECTS OF LACTOBACILLUS REUTERI METABOLITES IN HOUSE DUST MITE-STIMULATED T CELL RESPONSES IN VITRO 1. World Allergy Organ J, 11, 37, Comparison of microbiota and allergen profile in house dust from homes of allergic and non-allergic subjects – results from the GUSTO study, 12/2018, DOI: 10.1186/s40413-018-0212-5
42 Song Zhiwei (A/Prof) Ryan Haryadi Doctor of Philosophy Biochemistry THE ISOLATION, CHARACTERISATION, AND APPLICATION OF CHO GLYCOSYLATION MUTANT CELL LINES IN BIOTHERAPEUTICS 1. Bioengineered, 4, 90-94, CHO-gmt5, a novel CHO glycosylation mutant for producing afucosylated and asialylated recombinant antibodies, 04/2013, http://dx.doi.org/10.4161/bioe.22262

2. Glycobiology, 22, 897-911, Identification of functional elements of the GDP-fucose transporter SLC35C1 using a novel Chinese hamster ovary mutant, 04/2012, DOI: 10.1093/glycob/cws064

3. Plos one, 10, e0116878, Optimization of Heavy Chain and Light Chain Signal Peptides for High Level Expression of Therapeutic Antibodies in CHO Cells, 02/2015, DOI:  10.1371/journal. pone.0116878

43 Sudhakar Jha (Dr) Nishi Kumari Doctor of Philosophy Biochemistry IDENTIFYING THE ONCOGENIC ROLE OF USP10 IN BREAST CANCER 1.  Biochimica et Biophysica Acta (BBA)-Reviews on Cancer, 1868(2), 456-483, The roles of ubiquitin modifying enzymes in neoplastic disease, 12/2017, Published, Yes, DOI: 10.1016/j.bbcan.2017.09.002

2. Intechopen (Neoplasm), 8, 203-243, Targeting Ubiquitin Proteasome system in cancer, 09/2018, DOI: 10.5772/intechopen.69560

44 Tam Wai Leong (Tan Weiliang) (Dr) Azad Saei Doctor of Philosophy Biochemistry INVESTIGATING NOVEL MECHANISMS OF MAPK PATHWAY REGULATION IN MELANOMA 1.Journal of Experimental Medicine, 215, 1913-1928, Loss of USP28-mediated BRAF degradation drives resistance to RAF cancer therapies, 06/2018, DOI: 10.1084/jem.20171960

2. Journal of molecular & cellular oncology, 5, e1497862, Ubiquitination and adaptive responses to BRAF inhibitors in Melanoma, 09/2018, https://doi.org/10.1080/23723556.2018.1497862

45 Tan Boon Ooi, Patrick (Prof) Xu Chang Doctor of Philosophy Cancer Science Institute (CSI) CHARACTERIZATION OF HNF4a IN GASTRIC CANCER METABOLISM 1. Nature Communications, 7, 12983,  Epigenomic profiling of primary gastric adenocarcinoma reveals super-enhancer heterogeneity, 06/2016, DOI: 10.1038/ncomms12983
46 Tan Puay Hoon (Prof) Koh Cui Yun, Valerie Master of Science Anatomy METASTASIS IN MALIGNANT PHYLLODES TUMOURS OF THE BREAST – DEFINING PROGNOSTIC FACTORS 1. Applied Cancer Research, 37, 1-8, Distant metastases in phyllodes tumours of the breast: an overview, 07/2017,DOI: 10.1186/s41241-017-0028-6

2. Pathology, The utility of a targeted gene mutation panel in refining the diagnosis of breast phyllodes tumours, 08/2019, In Press

3. Virchows Archiv, 472, 615-621, Size and heterologous elements predict metastases in malignant phyllodes tumours of the breast, 10/2017, DOI:  10.1007/s00428-017-2257-1

47 Tan Yee Joo (A/Prof) James Odame Aboagye Doctor of Philosophy Microbiology and Immunology VIRUS-HOST INTERACTIONS OF THE MIDDLE EAST RESPIRATORY SYNDROME CORONAVIRUS (MERS-COV) NUCLEOCAPSID PROTEIN 1. Bioscience Reports, 38(5), 1-10, Overexpression of the nucleocapsid protein of Middle East Respiratory Syndrome coronavirus up-regulates CXCL10, 10/2018, DOI: 10.1042/BSR20181059
48 Thai Tran (A/Prof) Qiao Yongkang Doctor of Philosophy Physiology ROLE OF CD151 IN ASTHMA AND INFLUENZA INFECTION 1. Inhal Toxicol, 21, 1200-1207, Irritant and adjuvant effects of gaseous formaldehyde on the ovalbumin-induced hyperresponsiveness and inflammation in a rat model, 12/2009, DOI: 10.3109/08958370902806159

2. J Allergy Clin Immunol, 141, 1799-1817,  CD151, a novel host factor of nuclear export signaling in influenza virus infection., 05/2018, DOI: 10.1016/j.jaci.2017.11.032

3. J Allergy Clin Immunol, 139, 82-92.e5, CD151, a laminin receptor showing increased expression in asthmatic patients, contributes to airway hyperresponsiveness through calcium signaling, 01/2017, DOI: 10.1016/j.jaci.2016.03.029

49 Veronique Angeli (A/Prof) Lim Sheau Yng Doctor of Philosophy Microbiology and Immunology THE FUNCTION, ORIGIN AND MAINTENANCE OF LYVE-1-EXPRESSING MACROPHAGES 1. Immunity, 49, 1-16, Hyaluronan receptor LYVE-1-expressing macrophages maintain arterial tone through hyaluronan-mediated regulation of smooth muscle cell collagen, 08/2018, DOI: 10.1016/j.immuni.2018.06.008
50 Wang De Yun (Prof) Liu Jing Doctor of Philosophy Otolaryngology EFFECT AND UNDERLYING MECHANISMS OF INTERLEUKIN-13 (IL-13) ON THE BIOLOGICAL FUNCTIONS OF NASAL EPITHELIUM 1.Allergy, 73, 1673-1685, Role of IL-13Ra2 in modulating IL-13-induced MUC5AC and ciliary changes in healthy and CRSwNP mucosa., 03/2018,  DOI: 10.1111/all.13424

2. International forum allergy rhinology, 7, 304-311, Myrtol standardized affects mucociliary clearance, 03/2017, DOI:10.1002/alr.21878

3. The Journal of Infectious Diseases, 217, 906-915, In Vitro Model of Fully Differentiated Human Nasal Epithelial Cells Infected With Rhinovirus Reveals Epithelium-Initiated Immune Responses., 03/2018, DOI: 10.1093/infdis/jix640

51 Wong Tien Yin (Prof) Gavin Tan Siew Wei Doctor of Philosophy Ophthalmology DETERMINANTS, BIOMARKERS AND IMPACT OF DIABETIC RETINOPATHY IN ASIANS 1. Lancet Diabetes Endocrinol, 5, 143-155, Diabetic macular oedema., 02/2017, DOI: 10.1016/S2213-8587(16)30052-3.

2. Ophthalmology, 125, 529-536, Ethnic Differences in the Prevalence and Risk Factors of Diabetic Retinopathy: The Singapore Epidemiology of Eye Diseases Study, 04/2017, DOI: 10.1016/j.ophtha.2017.10.026.

52 Wong Tsun Hon, Peter (Prof) Zhao Hui Doctor of Philosophy Pharmacology POTENTIAL ROLES AND MECHANISMS OF MODULATOR OF APOPTOSIS (MOAP)-1 IN STRESS AND DEPRESSION 1. Mol. Neurobiol, 56, 2185-2201,Absence of Stress Response in Dorsal Raphe Nucleus in Modulator of Apoptosis 1-Deficient Mice, 07/2018, DOI:  10.1007/s12035-018-1205-7
53 Yanika Kowitlawakul (A/Prof) Teoh Yen Tjuin, Eugene Doctor of Philosophy Alice Lee Ctr for Nursing Stud EFFECTIVENESS OF A TRANSITION-TO-PRACTICE PROGRAMME FOR NEWLY QUALIFIED REGISTERED NURSES’ IN THEIR TRANSITION-TO-PRACTICE JOURNEY 1. Journal of Nursing Education and Practice, Lost in transition – Newly qualified Registered Nurses and their transition to practice journey in the first six months: A qualitative descriptive study, 03/2019, Accepted

2. Nurse Education Today, 33, 143-147,Lost in transition – A review of qualitative literature on newly qualified Registered Nurses’ experiences in their transition to practice journey, 06/2013, DOI: , 10.1016/j.nedt.2012.08.016

3. Singapore Nursing Journal, 40, 42-44, Research in brief – Lost in transition – Newly qualified Registered Nurses and their transition to practice journey : A qualitative descriptive study, 12/2013

54 Yap Suen Mei,Celestial Therese (A/Prof) Wang Liming Doctor of Philosophy Physiology PTEN-L IS A NOVEL PROTEIN PHOSPHATASE FOR UBIQUITIN DEPHOSPHORYLATION TO INHIBIT PINK1-PARKIN-MEDIATED MITOPHAGY 1. Autophagy, 14, 2023-2025, PTEN-L puts a brake on mitophagy, 09/2018, DOI: 10.1080/15548627.2018.1502565

2. Cell Research, 28, 787-802, PTEN-L is a novel protein phosphatase for ubiquitin dephosphorylation to inhibit PINK1-Parkin-mediated mitophagy, 06/2018, DOI: 10.1038/s41422-018-0056-0

3. Redox Biology, 19, 263-273,  Artesunate-induced mitophagy alters cellular redox status, 08/2018, DOI: 10.1016/j.redox.2018.07.025

55 Yew Wen Shan (A/Prof) Liow Lu Ting Doctor of Philosophy Biochemistry DEVELOPMENT OF GENETIC TOOLKIT AND SYNTHETIC CIRCUITRY IN CHROMOBACTERIUM VIOLACEUM FOR GOLD BIOLEACHING 1. Engineering biology, 2, Characterization of constitutive promoters from the Anderson library in Chromobacterium violaceum ATCC 12472., 10/2018, In Press
56 Yu, Hanry (Prof) Song Ziwei Doctor of Philosophy Physiology CELLULAR DYNAMICS OF LIVER REGENERATION FOR SMALL IN SITU INJURY 1. Advances in Experimental Medicine and Biology, 928, 419-433, Butein and Its Role in Chronic Diseases, 01/2016, DOI: 10.1007/978-3-319-41334-1_17

2. Seminars in Cell & Developmental Biology, 71, 153-167, Mechanosensing in Liver Regeneration, 11/2017, DOI: 10.1016/j.semcdb.2017.07.041

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A/Prof Kenneth Ban

Programme Director, National Supercomputing Cluster Singapore (NSCC)
Assoc Prof, Dept of Biochemistry, NUS Yong Loo Lin School of Medicine

Prof Kenneth Ban graduated from NUS Yong Loo Lin School of Medicine and completed his PhD in Stanford University, As a medical educator and Phase I Director at the Yong Loo Lin School of Medicine, Kenneth is leading the development of a Health Informatics track aiming to build foundational competencies in data science for medical students.

A/Prof Caroline Lee

Vice Dean, NUS Graduate School, NUS Yong Loo Lin School of Medicine
Assoc Prof, Dept of Biochemistry, NUS Yong Loo Lin School of Medicine

Prof Caroline Lee graduated with PhD from Baylor College of Medicine and did her post-doctoral training with Dr. Michael Gottesman at the National Cancer Institute, National Institutes of Health. She has ~100 peer reviewed publications focused on the functional genomics of hepatocellular carcinoma (HCC) and pharmacogenetics.

Aaron Chua

Principal Lecturer and Consultant
Digital Strategy & Leadership Practice
NUS-ISS

His research interests comprise health-related quality-of-life studies, clinical trials, and modelling transmission of infectious disease. He has also worked with projects in various therapeutic areas including oncology, stroke, ophthalmology and orthopaedics.

A/Prof Jason Yap

Associate Professor
NUS Saw Swee Hock School of Public Health

A/Prof Seth Gilbert

Dean’s Chair Associate Professor
Head, Department of Computer Science
NUS School of Computing

A/Prof Ngiam Kee Yuan

Head, AI Office, National University Health System
Head & Senior Consultant, Division of General Surgery (Endocrine & Thyroid Surgery), Department of Surgery, National University Hospital
Professor, Department of Surgery, NUS Yong Loo Lin School of Medicine
Senior Consultant, Division of Surgical Oncology, NCIS

Dr Aoife Keohane

• Programme Director, MSc in Behavioural and Implementation Sciences
in Health (MSc BIS)
• Senior Lecturer, Centre for Behavioural and Implementation
Science Interventions (BISI) NUS Yong Loo Lin School of Medicine

Prof Nick Sevdalis

• Academic Director, Centre for Behavioural and Implementation Science Interventions (BISI)
• Visiting Professor, Department of Psychological Medicine, NUS Yong Loo Lin School of Medicine
• Academic Director (Joint), Quality Improvement & Implementation Science Clinical Academic Group, King's Health Partners, London, UK

Dr Volker Patzel

Biomedical Innovation & Enterprise Course Coordinator
Senior Lecturer, Dept of Microbiology & Immunology, NUS Yong Loo Lin School of Medicine

Dr Volker Patzel is a Senior Lecturer at NUS Yong Loo Lin School of Medicine and holds a PhD from the Ruprecht Karls University in Heidelberg. With more than 20 years of teaching experience, he coordinates six modules at NUS Yong Loo Lin School of Medicine and leads research on RNA technologies for therapeutic and diagnostic applications. Dr Patzel has published over 50 papers, filed 15 patent families, and founded AVECRIS Pte Ltd in Singapore.

A/Prof Gautam Sethi

Drug Discovery and Development Specialisation Coordinator
Capstone Project Co-Coordinator
Associate Professor, Dept of Pharmacology, NUS Yong Loo Lin School of Medicine

A/Prof Gautam Sethi is a tenured Associate Professor at NUS Yong Loo Lin School of Medicine, focusing on oncogenic transcription factor activation and cancer therapy. His work has led to over 400 scientific publications in high-impact journals. A/Prof Sethi is an editorial board member for numerous international journals and has been recognized as one of the world’s most highly cited researchers in 2020 and 2021 by Clarivate.

Dr Sham Lok-To (Chris)

Capstone Project Coordinator
Assistant Professor, Dept of Microbiology & Immunology, NUS Yong Loo Lin School of Medicine

Dr Chris Sham is an Assistant Professor at the Department of Microbiology & Immunology, NUS Yong Loo Lin School of Medicine, where he teaches multiple microbiology-related courses, including Microbiology and Infection and Immunity He also serves as the Undergraduate Research Opportunities Programme coordinator and the Deputy Research Director of the Infectious Diseases Translational Research Programme. His research focuses on bacterial cell envelope synthesis, and in 2019, he received the prestigious National Research Foundation Fellowship.

Dr Png Chin Wen

Vaccinology and Immunotherapy Specialisation Coordinator
Lecturer, Dept of Microbiology & Immunology, NUS Yong Loo Lin School of Medicine

Dr Png Chin Wen earned his PhD from the University of Queensland and is a Lecturer at NUS Yong Loo Lin School of Medicine, where he teaches topics such as immunology, cellular signaling, and vaccine development. His research focuses on gut microbiome and mucosal inflammation related to gastrointestinal cancers. Dr Png collaborates with clinicians to explore the role of gut bacteria in disease progression and serves as course coordinator for the MSc in Applied Biomedicine’s Vaccinology and Immunotherapy specialisation.

Dr Jaishree Tripathi

Infectious Diseases Management Specialisation Coordinator
Lecturer, Dept of Microbiology & Immunology, NUS Yong Loo Lin School of Medicine

Dr Jaishree Tripathi is a Lecturer at the Yong Loo Lin School of Medicine, where she leads the Infectious Diseases Management track for the MSc in Applied Biomedicine programme. She has over 11 years of research experience in malaria parasite biology, including drug resistance and host-parasite interactions. Dr Tripathi holds a PhD in Biological Sciences from the University of Cambridge and has made significant contributions to malaria research using stem-cell-based models and single-cell transcriptomics.

A/Prof Zhang Yongliang

Co-Programme Director, MSc in Applied Biomedicine (ABM)
Associate Professor, Dept of Microbiology & Immunology, NUS Yong Loo Lin School of Medicine

A/Prof Zhang Yongliang is a tenured Associate Professor and Deputy Research Director of the Translational Immunology Programme at NUS Yong Loo Lin School of Medicine. With over 15 years of teaching experience, he has created several programmes focused on infection and cancer. A/Prof Zhang’s contributions to immunology research have earned him recognition, including the Graduate Mentor of the Year award in 2019.

A/Prof Kevin Tan Shyong Wei

Programme Director, MSc in Applied Biomedicine (ABM)
Associate Professor and Head, Dept of Microbiology & Immunology, NUS Yong Loo Lin School of Medicine

A/Prof Kevin Tan is the Head of the Department of Microbiology & Immunology at NUS and Vice-Dean (Graduate Studies) at the Yong Loo Lin School of Medicine. He has 20 years of teaching experience and played a key role in developing the world’s first online course on the biomedical aspects of COVID-19. A/Prof Tan has received numerous teaching awards, including the Faculty Teaching Excellence Award and Graduate Mentor of the Year.

Dr Lee Chun Fan

Assistant Professor, Centre for Quantitative Medicine, Duke-NUS Medical School

Dr Lee Chun Fan is an assistant professor at the Centre for Quantitative Medicine at the Duke-NUS Medical School. Prior to this, he was also affiliated with the Division of Epidemiology and Biostatistics in the School of Public Health at The University of Hong Kong and the Singapore Clinical Research Institute.
His research interests comprise health-related quality-of-life studies, clinical trials, and modelling transmission of infectious disease. He has also worked with projects in various therapeutic areas including oncology, stroke, ophthalmology and orthopaedics.

Dr Cindy Lin Xinyi

Assistant Professor, Centre for Quantitative Medicine, Duke-NUS Medical School

Dr. Xinyi (Cindy) Lin is an Assistant Professor at the Centre for Quantitative Medicine, Duke- NUS Medical School. She serves as the course coordinator for two modular courses in in the MCI programme: MCI5001 (Design and Planning of Clinical Studies) and MCI5006 (Design and Planning of Epidemiological Studies). Dr. Lin has extensive experience utilising advanced statistical methods in clinical research studies and genetic epidemiology investigations. She has taught biostatistics coursework to a diverse audience, including PhD students and clinical researchers.

Mihir Gandhi

Assistant Professor, Centre for Quantitative Medicine, Duke-NUS Medical School

Mihir Gandhi is an Assistant Professor in the Signature Program in Health Services & Systems Research, Lien Centre for Palliative Care, as well as the Head of Biostatistics Core team at the Centre for Quantitative Medicine, Duke-NUS Medical School, Singapore. He is also affiliated with the Singapore Clinical Research Institute, Singapore as the Head of Biostatistics Department and the Global Health Group at the Center for Child Health Research, Tampere University, Finland as a Visiting Researcher.
He is primarily working on planning, analysis and reporting of clinical trials. He has experience in wide range of therapeutic areas such as oncology, paediatrics, and hypertension for drug and health services interventional trials. In addition to clinical trials, he has research interest in applied statistics, health-related quality of life, quality of healthcare and health state valuation.

A/Prof Edwin Chan

Associate Professor, Centre for Quantitative Medicine
Office of Clinical Sciences, Duke-NUS Medical School

A/Prof Chan is a clinical epidemiologist with over twenty years of experience in clinical research and evidence synthesis as the Chief Scientific Officer of the Singapore Clinical Research Institute (SCRI). He has been the Director of Cochrane Singapore since its establishment and is currently the Senior Scientific Advisor to SCRI. He teaches research literature critical appraisal skills and mentors students in clinical research (MCI programme, NUS). He has taught many research methodology courses on clinical trials, biostatistics, epidemiology, clinical practice guidelines (CPG) development, meta-analysis & evidence- based medicine (EBM). His interests are in the teaching of critical appraisal skills, epidemiology, health technology assessment and evidence synthesis.

Prof Cheung Yin Bun

Professor, Centre for Quantitative Medicine
Deputy Director, Centre for Quantitative Medicine, Duke-NUS Medical School

CHEUNG Yin Bun is Professor at Duke-NUS Medical School, Singapore, and Adjunct Professor at Tampere University, Finland. Prior to joining Duke-NUS, he was a Senior Lecturer at the London School of Hygiene & Tropical Medicine and Chief Scientific Officer at the Singapore Clinical Research Institute.
He received his degrees in social science, medical demography, statistics and paediatric epidemiology from institutions in Hong Kong, Singapore, and the United Kingdom. He has broad interest in the studies of global child health, statistical methodology, and quality of life in palliative care setting. He has been the principal investigator of multiple research grants on statistical methodology and quality of life research. He is the author of Statistical Analysis of Human Growth and Development (CRC Press, 2014) and co-author of Survival Analysis: A Practical Approach (Wiley, 2006). He is the developer of the Singapore Caregiver Quality of Life Scale.

Makoto Yawata,M.D., Ph.D.

Programme Director and Clinical-Scientist Mentor
Research Assistant Professor
Department of Pediatrics, NUS Yong Loo Lin School of Medicine Principal Investigator, Immunology Programme, Life Sciences Institute, National University of Singapore Principal Investigator, NUSMED Immunology Translational Research Programme, National University of Singapore

Makoto YAWATA is the Director of the MCI Programme, where he also serves as a clinician-scientist mentor guiding the students in designing and planning their clinical studies and as coordinator of the MCI wet lab experiential research workshop. He is affiliated with the Department of Paediatrics at the NUS Yong Loo Lin School of Medicine and a Principal Investigator in the Immunology Programme in the NUS Life Sciences Institute and the NUS Medicine Immunology Translational Research Programme. His clinical background is autoimmune diseases; however the research he conducted as postdoctoral fellow in the Department of Structural Biology in Stanford University School of Medicine has led him to become more involved in hematology and transplantation. His laboratory has been investigating the mechanisms of human natural killer cell responses against particular types of virus infections and cancer, and also in transplantation immunology.

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