Drinking coffee or tea may be beneficial for physical function in ageing   

23 Jun 2025

Assoc Prof Brian D Earp appointed co-editor-in-chief for JME

Associate Professor Brian D. Earp of the Yong Loo Lin School of Medicine, National University of Singapore (NUS Medicine) has been appointed the next Co-Editor-in-Chief of the Journal of Medical Ethics (JME), one of the world’s leading platforms for ethical scholarship in medicine and healthcare. An Associate Professor of Biomedical Ethics in the Centre for Biomedical Ethics at NUS Medicine, Assoc Prof Earp also holds courtesy appointments as Associate Professor of Philosophy and of Psychology at NUS, reflecting his wide-ranging interdisciplinary expertise. Before joining NUS, Assoc Prof Earp was a Senior Research Fellow in the Faculty of Philosophy at the University of Oxford. He is an elected member of the UK Young Academy, an initiative of the British Academy and the Royal Society, recognising early-career researchers of exceptional achievement and promise. At NUS, he directs both the Oxford-NUS Centre for Neuroethics and Society and the EARP Lab (Experimental Bioethics, Artificial Intelligence, and Relational Moral Psychology Lab).

20 Jun 2025

More than just menopause – How muscle, fat and a simple blood test can predict midlife women’s health

New research from the Integrated Women’s Health Programme (IWHP) at the National University Hospital (NUH) and the Yong Loo Lin School of Medicine, National University of Singapore (NUS Medicine), has uncovered new insights into how muscle strength and visceral fat, and their association with menopause, can potentially lead to downstream health impacts among women in Singapore, and how physical performance assessments and a simple blood test could help predict and prevent chronic conditions before they arise.

16 Jun 2025

NUS Medicine study finds key blood proteins which predict future cognitive decline

In a study that holds significance for individuals with cerebrovascular disease, scientists from the Yong Loo Lin School of Medicine, National University of Singapore (NUS Medicine), have found proteins in the blood that predict future cognitive decline and dementia. Led by Professor Christopher Chen, Deputy Chair of the Healthy Longevity Translational Research Programme (TRP) at NUS Medicine, this first-of-its-kind study in Singapore analysed more than 1,000 proteins in the blood of a local patient cohort. The study was conducted on 528 patients from memory clinics at the National University Hospital (NUH) and St Luke’s Hospital in Singapore. Professor Arthur Mark Richards, co-senior author of the paper published in Alzheimer’s and Dementia, said, “One of our findings was the characterisation of a blood protein signature for future cognitive decline. Using advanced proteomic technologies, we profiled over a thousand blood proteins tied to neurodegeneration, inflammation, and vascular dysfunction, which are key contributors to dementia.” Prof Richards is from the Cardiovascular-Metabolic Diseases TRP at NUS Medicine.

12 Jun 2025

Repurposed cancer drugs found to promote stroke recovery, limit brain damage

A recent study by researchers from the Yong Loo Lin School of Medicine, National University of Singapore (NUS Medicine), has shown that a class of drugs, HDACi (histone deacetylase inhibitors), protects neurons and limits brain damage following stroke by altering the gene expression of microglia, the immune cells of the brain. HDACi are currently used or being tested as treatments for certain cancers and are also being researched for neurological conditions such as Alzheimer’s disease.

11 Jun 2025

AI designs drug combinations specifically for women or men to optimise heart valve disease treatment

09 Jun 2025

NUS Medicine researchers develop a better and more accurate biological ageing clock

Researchers from the Yong Loo Lin School of Medicine, National University of Singapore (NUS Medicine) have developed an improved biological ageing clock, LinAge2, that offers doctors a practical and more accurate way to assess how quickly a person is ageing, and what can be done to slow it down.

03 Jun 2025

Endocrinologists asked to step up efforts to reduce carbon footprint of healthcare

A new international review led by researchers from the Yong Loo Lin School of Medicine, National University of Singapore (NUS Medicine), has highlighted the often-overlooked environmental impact of healthcare, especially in endocrinology.

27 May 2025

NUS Medicine and IHME joint Lancet Publications

Singapore has achieved exceptional public health successes while confronting emerging challenges, according to a series of four new studies published in the Lancet Public Health. Jointly led by the Yong Loo Lin School of Medicine, National University of Singapore (NUS Medicine) and the Institute for Health Metrics and Evaluation (IHME), University of Washington School of Medicine, this special series is the first of its kind research focused on injuries, cardiovascular disease (CVD), smoking prevalence, and mental health burden in the ASEAN region. “The findings present a nuanced picture of Singapore’s health progress. While we’ve made remarkable strides in areas like cardiovascular care and tobacco control, the growing burden of mental health conditions and injuries, particularly self-harm and falls, calls for urgent and sustained attention,” said lead author Dr Marie Ng, Associate Professor, NUS Medicine, and Affiliate Associate Professor at IHME.

08 May 2025

Professor Shawn Chen appointed founding Editor-in-Chief of newly launched ACS Nano Medicine

Professor Xiaoyuan (Shawn) Chen, Nasrat Muzayyin Chair Professor in Medicine and Technology, Yong Loo Lin School of Medicine, National University of Singapore (NUS Medicine), has been appointed the founding Editor-in-Chief of ACS Nano Medicine, a new peer-reviewed hybrid journal published by the American Chemical Society (ACS).

07 May 2025

Flagship Pioneering, the National University of Singapore, National University Hospital and the National University Health System Announce Collaboration to Advance Biotech Research & Development

Flagship Pioneering, the bioplatform innovation company, the Yong Loo Lin School of Medicine, National University of Singapore (NUS Medicine), National University Hospital (NUH) and the National University Health System (NUHS) today announced a research and development collaboration to advance outcomes in human health and sustainability. Flagship, NUS Medicine, NUH and NUHS outlined the goals of their collaboration via a Memorandum of Understanding (MOU) signed this week.