Prof-Chong-Yap-Seng

Prof Chong Yap Seng

ORCID: 0000-0002-7232-8473

Appointment(s)

Lien Ying Chow Professor in Medicine
Dean, NUS Yong Loo Lin School of Medicine (NUS Medicine)
Deputy Chief Executive (Education & Research), National University Health System



Degree(s)

2017 – Harvard Business School Executive Education (GMP)

2006 – National University of Singapore (M.D)

1998 – Academy of Medicine, Singapore (FAMS – O&G)

1995 – Royal Australian College of Obstetricians & Gynaecologists (MRACOG)

1995 – National University of Singapore (MMED – O&G)

1988 – National University of Singapore (MBBS)



Biography

Professor Chong Yap Seng is the Dean of the Yong Loo Lin School of Medicine at the National University of Singapore. Since assuming the deanship in 2019, NUS Medicine has risen to 13th place in the 2026 Times Higher Education World University Rankings (Medical & Health) and 17th place in the 2026 QS World University Rankings for Medicine.

As Deputy Chief Executive for Education and Research at the National University Health System (NUHS), Professor Chong advances NUHS’ academic mission by overseeing academic and research development across its institutions. Recently appointed the Executive Director of Singapore’s first RIE Grand Challenge (RIE GC) on Maximising Healthy and Successful Longevity (MHSL), he will spearhead the development of scientific innovations and evidence-based solutions to extend healthspan in a super-aging Singapore. As the Chief Clinical Officer at the Institute for Human Development and Potential, Agency for Science, Technology and Research (A*STAR), he oversees clinical programmes that seek to promote health and human capacity in Singapore and beyond.

Professor Chong is the lead principal investigator of two of Singapore’s most prominent birth cohort studies: Growing Up in Singapore Towards healthy Outcomes (GUSTO) and the Singapore Preconception Study of long-Term maternal and child Outcomes (S-PRESTO). He has co-authored close to 700 research publications in leading international journals to date. His research excellence has been recognised with numerous honours, including the National Outstanding Clinician Scientist Award (2017) from Singapore’s Ministry of Health and the Public Administration Medal (Silver) at the 2022 Singapore National Day Awards.

Driven by a lifelong belief in the power of science to optimise human potential and by his interest in the Developmental Origins of Health and Disease, Professor Chong’s energies throughout his career have been focused on bridging medicine with other disciplines and sectors, both locally and internationally. His efforts to refocus medical education on health was recognised with an honorary doctorate from the University of Zurich and in recognition of his longstanding contributions to medical science and global health, Professor Chong was conferred the ATOM Lifetime Outstanding Achievement Award for Healthcare.

An obstetrician by training, Professor Chong continues to serve as Senior Consultant in the Department of Obstetrics & Gynaecology at the National University Hospital and still takes joy in welcoming newborns into the world.


Selected Publications

Oral short-chain fatty acid-producing bacteria may be associated with biological age and cognition among the oldest old.

Wehnes T, Wang W, Tay JH, Guan L, Feng L, Ho CMR, Ng TP, Kennedy BK, Venkitaraman A, Koh WP, Chong YS, Maier AB. 2026

Ethical considerations in AI for child health and recommendations for child-centered medical AI.

Chng SY, Tern MJW, Lee YS, Cheng LT, Kapur J, Eriksson JG, Chong YS, Savulescu J. 2025

Life stage impact on the human skin ecosystem: lipids and the microbial community.

Pagac MP, Davient B, Plado LA, Lam HYI, Lee SM, Ravikrishnan A, Chua WLE, Muralidharan S, Sridharan A, Irudayaswamy AS, Srinivas R, Wearne S, Mohamed Naim AN, Ho EXP, Ng HQA, Kwah JS, Png E, Bendt AK, Wenk MR, Torta F, Nagarajan N, Common J, Chong YS, Tham EH, Shek LP, Loo EXL, Chambers J, Yew YW, Loh M, Dawson TL Jr. 2025

Effect of an Asian-adapted Mediterranean diet and pentadecanoic acid on fatty liver disease: the TANGO randomized controlled trial

Chooi YC, Zhang QA, Magkos F, Ng M, Michael N, Wu X, Volchanskaya VSB, Lai X, Wanjaya ER, Elejalde U, Goh CC, Yap CPL, Wong LH, Lim KJ, Velan SS, Yaligar J, Muthiah MD, Chong YS, Loo EXL, Eriksson JG; TANGO Study Group. 2024

A global multicohort study to map subcortical brain development and cognition in infancy and early childhood

Alex AM, Aguate F, Botteron K, Buss C, Chong YS, Dager SR, Donald KA, Entringer S, Fair DA, Fortier MV, Gaab N, Gilmore JH, Girault JB, Graham AM, Groenewold NA, Hazlett H, Lin W, Meaney MJ, Piven J, Qiu A, Rasmussen JM, Roos A, Schultz RT, Skeide MA, Stein DJ, Styner M, Thompson PM, Turesky TK, Wadhwa PD, Zar HJ, Zöllei L, de Los Campos G, Knickmeyer RC; ENIGMA ORIGINs group. 2024

Gestational diabetes mellitus and development of intergenerational overall and subtypes of cardiovascular diseases: a systematic review and meta-analysis.

Chen A, Tan B, Du R, Chong YS, Zhang C, Koh AS, Li LJ. 2024

The effectiveness of Parentbot - a digital healthcare assistant - on parenting outcomes: A randomized controlled trial.

Chua JYX, Choolani M, Chee CYI, Yi H, Chan YH, Lalor JG, Chong YS, Shorey S. 2024

Exploring multi-omics and clinical characteristics linked to accelerated biological aging in Asian women of reproductive age: insights from the S-PRESTO study.

Chen L, Tan KM, Xu J, Mishra P, Mir SA, Gong M, Narasimhan K, Ng B, Lai JS, Tint MT, Cai S, Sadananthan SA, Michael N, Yaligar J, Velan SS, Leow MKS, Tan KH, Chan J, Meaney MJ, Chan SY, Chong YS, Eriksson JG. 2024