Appointment(s)
Lien Ying Chow Professor in Medicine
Dean, NUS Yong Loo Lin School of Medicine (NUS Medicine)
Deputy Chief Executive (Education & Research), National University Health System
Biography
As Deputy Chief Executive for Education and Research at the National University Health System (NUHS), Professor Chong advances NUHS’ academic mission by overseeing academic and research development across its institutions. Recently appointed the Executive Director of Singapore’s first RIE Grand Challenge (RIE GC) on Maximising Healthy and Successful Longevity (MHSL), he will spearhead the development of scientific innovations and evidence-based solutions to extend healthspan in a super-aging Singapore. As the Chief Clinical Officer at the Institute for Human Development and Potential, Agency for Science, Technology and Research (A*STAR), he oversees clinical programmes that seek to promote health and human capacity in Singapore and beyond.
Professor Chong is the lead principal investigator of two of Singapore’s most prominent birth cohort studies: Growing Up in Singapore Towards healthy Outcomes (GUSTO) and the Singapore Preconception Study of long-Term maternal and child Outcomes (S-PRESTO). He has co-authored close to 700 research publications in leading international journals to date. His research excellence has been recognised with numerous honours, including the National Outstanding Clinician Scientist Award (2017) from Singapore’s Ministry of Health and the Public Administration Medal (Silver) at the 2022 Singapore National Day Awards.
Driven by a lifelong belief in the power of science to optimise human potential and by his interest in the Developmental Origins of Health and Disease, Professor Chong’s energies throughout his career have been focused on bridging medicine with other disciplines and sectors, both locally and internationally. His efforts to refocus medical education on health was recognised with an honorary doctorate from the University of Zurich and in recognition of his longstanding contributions to medical science and global health, Professor Chong was conferred the ATOM Lifetime Outstanding Achievement Award for Healthcare.
An obstetrician by training, Professor Chong continues to serve as Senior Consultant in the Department of Obstetrics & Gynaecology at the National University Hospital and still takes joy in welcoming newborns into the world.
Prevalence and incidence of postpartum depression among healthy mothers: A systematic review and meta-analysis
Sep 2018 JOURNAL OF PSYCHIATRIC RESEARCH104:235-248 (14 pages) PERGAMON-ELSEVIER SCIENCE LTD
Co-authors: Shorey S, Chee CYI, Ng ED, Chan YH, Tam WWS, Chong YS
Prenatal maternal depression alters amygdala functional connectivity in 6-month-old infants
17 Feb 2015 TRANSLATIONAL PSYCHIATRY5:7 pages
NATURE PUBLISHING GROUP
Co-authors: Qiu A, Anh TT, Li Y, Chen H, Rifkin-Graboi A, Broekman BFP, Kwek K, Saw S-M, Chong Y-S, Gluckman PD, Fortier MV, Meaney M
Cohort Profile: Growing Up in Singapore Towards healthy Outcomes (GUSTO) birth cohort study
Oct 2014 INTERNATIONAL JOURNAL OF EPIDEMIOLOGY43(5):1401-1409 (9 pages) OXFORD UNIV PRESS
Co-authors: Soh S-E, Tint MT, Gluckman PD, Godfrey KM, Rifkin-Graboi A, Chan YH, Stuenkel W, Holbrook JD, Kwek K, Chong Y-S, Saw SM
The effect of genotype and in utero environment on interindividual variation in neonate DNA methylomes
Jul 2014 GENOME RESEARCH24(7):1064-1074 (11 pages) COLD SPRING HARBOR LAB PRESS, PUBLICATIONS DEPT
Co-authors: Ai LT, Pan H, Chen L, Ong M-L, Dogra S, Wong J, MacIsaac JL, Mah SM, McEwen LM, Saw S-M, Godfrey KM, Chong Y-S, Kwek K, Kwoh C-K, Soh S-E, Chong MFF, Barton S, Karnani N, Cheong CY, Buschdorf JP, Stunkel W, Kobor MS, Meaney MJ, Gluckman PD, Holbrook JD
Prenatal Maternal Depression Associates with Microstructure of Right Amygdala in Neonates at Birth
1 Dec 2013 BIOLOGICAL PSYCHIATRY74(11):837-844 (8 pages) ELSEVIER SCIENCE INC
Co-authors: Rifkin-Graboi A, Bai J, Chen H, Hameed WB, Sim LW, Tint MT, Leutscher-Broekman B, Chong Y-S, Gluckman PD, Fortier MV, Meaney MJ, Qiu A
Safer childbirth: avoiding medical interventions for non-medical reasons
6 Feb 2010 LANCET375(9713):440-442 (3 pages) ELSEVIER SCIENCE INC
Co-authorsChong Y-S, Kwek KYC
Carbetocin versus syntometrine for the third stage of labour following vaginal delivery-a double-blind randomised controlled trial
Oct 2009 BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY116(11):1461-1466 (6 pages) WILEY
Co-authors: Su LL, Rauff M, Chan YH, Suphan NM, Lau TP, Biswas A, Chong YS
Antenatal education and postnatal support strategies for improving rates of exclusive breast feeding: randomised controlled trial
22 Sep 2007BMJ-BRITISH MEDICAL JOURNAL335(7620):596-599 (6 pages) BMJ PUBLISHING GROUP
Co-authors: Su L-L, Chong Y-S, Chan Y-H, Chan Y-S, Fok D, Tun K-T, Ng FSP, Rauff M
Identification of nestin-positive putative mammary stem cells in human breastmilk
Jul 2007 CELL AND TISSUE RESEARCH329(1):129-136 (8 pages) SPRINGER
Co-authors: Cregan MD, Fan Y, Appelbee A, Brown ML, Klopcic B, Koppen J, Mitoulas LR, Piper KME, Choolani MA, Chong Y-S, Hartmann PE
Simple antenatal preparation to improve breastfeeding practice - A randomized controlled trial
Jan 2007 Conference of the NATO-Advanced-Study-Institute on Optimising Detectors, Imaging and Computing Technologies form Nuclear Physics in General and Security Applications OBSTETRICS AND GYNECOLOGY109(1):73-80 (8 pages) LIPPINCOTT WILLIAMS & WILKINS
Co-authors: Mattar CN, Chong Y-S, Chan Y-S, Chew A, Tan P, Chan Y-H, Rauff MH-J
Misoprostol for preventing PPH: some lessons learned
7 Oct 2006LANCET368(9543):1216-1218 (3 pages) ELSEVIER SCIENCE INC
Co-authors:Chong Y-S, Su L-L
Association between breastfeeding and likelihood of myopia in children
22 Jun 2005 JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION293(24):3001-3002 (2 pages) AMER MEDICAL ASSOC
Co-authors: Chong YS, Liang Y, Tan D, Gazzard G, Stone RA, Saw SM
Dynamics of Infant Gut Microbiota Are Influenced by Delivery Mode and Gestational Duration and Are Associated with Subsequent Adiposity
MBIO6(1):9 pages AMER SOC MICROBIOLOGY
Co-authors: Dogra S, Sakwinska O, Soh S-E, Ngom-Bru C, Brueck WM, Berger B, Bruessow H, Lee YS, Yap F, Chong Y-S, Godfrey KM, Holbrook JD
Low birthweight and subsequent obesity in Japan
LANCET369 (9567):1081-1082 (2 pages) ELSEVIER SCIENCE INC
Co-authors: Gluckman PD, Chong YS, Fukuoka H, Beedle AS, Hanson MA
