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Professor Chong Yap Seng

Professor Chong Yap Seng

Professor Chong Yap Seng

obgcys@nus.edu.sg

Professor Yap-Seng Chong is a Senior Consultant in the Department of Obstetrics & Gynaecology at the National University Hospital (NUH), and a member of the Executive Group of the National University Health System (NUHS) as well as a board member of the National Medical Research Council. As a respected clinician and researcher with a profound interest in women’s health and early development, he is the Lead Principal Investigator of the National Research Foundation Translational and Clinical Research Flagship Program on the Developmental Origins of Health and Disease. He has also been the Executive Director of the Singapore Institute for Clinical Sciences, Agency for Science, Technology and Research (A*STAR) since 2015. Presently, Professor Yap-Seng Chong has been the Dean of the Yong Loo Lin School of Medicine, National University of Singapore, since 1 January 2019.

Yap-Seng has well over 300 peer-reviewed research publications covering topics like the genetic epidemiology of pregnancy-related disorders, intrapartum and postpartum management, natural childbirth, strategies to promote breastfeeding, and the developmental origins of health and disease. He has formed multiple academic and industry collaborations with a particular focus in the area of early human development and nutrition, with research grant funding of more than $100 million.

Publications

  1. Soh, S. E., Tint, M. T., Gluckman, P. D., Godfrey, K. M., Rifkin-Graboi, A., Chan, Y. H., Stünkel, W., Holbrook, J. D., Kwek, K., Chong, Y. S., Saw, S. M., & GUSTO Study Group (2014). Cohort profile: Growing Up in Singapore Towards healthy Outcomes (GUSTO) birth cohort study. International journal of epidemiology, 43(5), 1401–1409. https://doi.org/10.1093/ije/dyt125
  2. Teh, A. L., Pan, H., Chen, L., Ong, M. L., Dogra, S., Wong, J., MacIsaac, J. L., Mah, S. M., McEwen, L. M., Saw, S. M., Godfrey, K. M., Chong, Y. S., Kwek, K., Kwoh, C. K., Soh, S. E., Chong, M. F., Barton, S., Karnani, N., Cheong, C. Y., Buschdorf, J. P., … Holbrook, J. D. (2014). The effect of genotype and in utero environment on interindividual variation in neonate DNA methylomes. Genome research, 24(7), 1064–1074. https://doi.org/10.1101/gr.171439.113
  3. Dogra, S., Sakwinska, O., Soh, S. E., Ngom-Bru, C., Brück, W. M., Berger, B., Brüssow, H., Lee, Y. S., Yap, F., Chong, Y. S., Godfrey, K. M., Holbrook, J. D., & GUSTO Study Group (2015). Dynamics of infant gut microbiota are influenced by delivery mode and gestational duration and are associated with subsequent adiposity. mBio, 6(1), e02419-14. https://doi.org/10.1128/mBio.02419-14
  4. Soh, S. E., Aw, M., Gerez, I., Chong, Y. S., Rauff, M., Ng, Y. P., Wong, H. B., Pai, N., Lee, B. W., & Shek, L. P. (2009). Probiotic supplementation in the first 6 months of life in at risk Asian infants--effects on eczema and atopic sensitization at the age of 1 year. Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 39(4), 571–578. https://doi.org/10.1111/j.1365-2222.2008.03133.x
  5. Su, L. L., Chong, Y. S., Chan, Y. H., Chan, Y. S., Fok, D., Tun, K. T., Ng, F. S., & Rauff, M. (2007). Antenatal education and postnatal support strategies for improving rates of exclusive breast feeding: randomised controlled trial. BMJ (Clinical research ed.), 335(7620), 596. https://doi.org/10.1136/bmj.39279.656343.55
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