Terminal Illness

Chronic-Illness-and-Long-term-Care-Level-2-4

The management of terminal illness requires a multi-disciplinary approach.

It requires an effort in supporting symptom management as well as psychological, emotional, and spiritual health and well-being. Hence, the Chronic Illness and Long-term Care research in NUS Nursing focuses on understanding patient, family and healthcare provider perspectives and experiences in terminal illness management, developing improved service delivery programmes, and supporting professional education initiatives and training. Ultimately, the goal is to provide excellent supportive and palliative care services by returning autonomy and control in terminal illness management to patients and their loved ones.

Core Member: Prof Hong-Gu HE, Dr Darryl ANG

Publications

  • Kim NR, Lee JY, Park J, Lau ST.. Ecological predictors of cultural competence among nurses in the neonatal intensive care unit: A cross-sectional descriptive study. Nurs Health Sci. 2024 Jun;26(2):e13115. doi: 10.1111/nhs.13115.. 10.1111/nhs.13115

  • Yen KY, Cheng JY, Li JQ, Toh ZA, He HG.. The effectiveness of digital psychosocial interventions on psychological distress, depression, anxiety, and health-related quality of life in patients with gynaecological cancer: a systematic review and meta-analysis. Support Care Cancer. 2024 Mar 21;32(4):240. doi: 10.1007/s00520-024-08415-4.. 10.1007/s00520-024-08415-4

  • Leo CSY, Cheng LJ, Lam XR, He H.. Global prevalence and factors associated with preoperative depression in women undergoing breast surgery: a meta-analysis and meta-regression. Breast Cancer Res Treat. 2024 Mar 16. doi: 10.1007/s10549-023-07216-3. Online ahead of print.. 10.1007/s10549-023-07216-3

  • Yoong SQ, Bhowmik P, Kapparath S, Porock D.. Palliative prognostic scores for survival prediction of cancer patients: a systematic review and meta-analysis. J Natl Cancer Inst. 2024 Feb 15:djae036. doi: 10.1093/jnci/djae036. Online ahead of print.. 10.1093/jnci/djae036

  • Li J, Yin YZ, Zhang J, Puts M, Li H, Lyu MM, Wang AN, Chen OY, Zhang JP.. A latent profile analysis of resilience and their relation to differences in sleep quality in patients with lung cancer. Support Care Cancer. 2024 Feb 13;32(3):155. doi: 10.1007/s00520-024-08337-1.. 10.1007/s00520-024-08337-1

  • Yoong SQ, Schmidt LT, Chao FFT, Devi KM, Wang W, Zhang H.. Nursing students' perspectives and learning experiences of participating in a palliative and end-of-life care simulation programme: A qualitative study. Nurse Educ Today. 2024 Mar;134:106103. doi: 10.1016/j.nedt.2024.106103. Epub 2024 Jan 24.. 10.1016/j.nedt.2024.106103

  • Zhi S, Gu W, Miao R, Zhang L, Jing X, Ramachandran HJ, Wang W.. Associations between dyadic communication and dyadic coping of patients with cervical cancer and their spouses: a study utilizing the actor-partner interdependence model. Support Care Cancer. 2024 Jan 8;32(2):90. doi: 10.1007/s00520-023-08304-2.. 10.1007/s00520-023-08304-2

  • Rajendran P, Jarasiunaite-Fedosejeva G, İsbir GG, Shorey S.. Healthy siblings' perspectives about paediatric palliative care: A qualitative systematic review and meta-synthesis. Palliat Med. 2024 Jan;38(1):25-41. doi: 10.1177/02692163231217597. Epub 2023 Dec 12.. 10.1177/02692163231217597

  • Mohamed E, García Martínez DJ, Hosseini MS, Yoong SQ, Fletcher D, Hart S, Guinn BA.. Identification of biomarkers for the early detection of non-small cell lung cancer: a systematic review and meta-analysis. Carcinogenesis. 2024 Feb 12;45(1-2):1-22. doi: 10.1093/carcin/bgad091.. 10.1093/carcin/bgad091

  • Low NJH, Leow DGW, Klainin-Yobas P.. Effectiveness of Technology-Based Psychosocial Interventions on Psychological Outcomes Among Adult Cancer Patients and Caregivers: A Systematic Review and Meta-Analysis. Semin Oncol Nurs. 2024 Feb;40(1):151533. doi: 10.1016/j.soncn.2023.151533. Epub 2023 Nov 15.. 10.1016/j.soncn.2023.151533

  • Ang WR, Ang WHD, Cham SQG, de Mel S, Chew HSJ, Devi MK.. Effectiveness of resilience interventions among cancer patients - A systematic review, meta-analysis, and meta-regression of randomised controlled trials. Eur J Oncol Nurs. 2023 Dec;67:102446. doi: 10.1016/j.ejon.2023.102446. Epub 2023 Oct 14.. 10.1016/j.ejon.2023.102446

  • Tan JYA, Ong GYQ, Cheng LJ, Pikkarainen M, He HG.. Effectiveness of mHealth-based psychosocial interventions for breast cancer patients and their caregivers: A systematic review and meta-analysis. J Telemed Telecare. 2023 Aug 31:1357633X231187432. doi: 10.1177/1357633X231187432. Online ahead of print.. 10.1177/1357633X231187432

  • Yoong SQ, Schmidt LT, Devi KM, Zhang H.. Using palliative and end-of-life simulation to enhance pre-licensure nursing students' emotional intelligence, palliative care knowledge and reflective abilities: A single group, pretest-posttest study. Nurse Educ Today. 2023 Nov;130:105923. doi: 10.1016/j.nedt.2023.105923. Epub 2023 Aug 2.. 10.1016/j.nedt.2023.105923

  • Cheng WH, Teo RH, Cheng LJ, Lau Y, Lau ST.. Global prevalence of sleep disturbances among breast cancer survivors: A systematic review with meta-analysis. Sleep Health. 2023 Oct;9(5):704-716. doi: 10.1016/j.sleh.2023.04.004. Epub 2023 Jul 13.. 10.1016/j.sleh.2023.04.004

  • Yoong SQ, Porock D, Whitty D, Tam WWS, Zhang H.. Performance of the Palliative Prognostic Index for cancer patients: A systematic review and meta-analysis. Palliat Med. 2023 Sep;37(8):1144-1167. doi: 10.1177/02692163231180657. Epub 2023 Jun 13.. 10.1177/02692163231180657

  • Ong JW, Ong QO, Metsävainio T, Vaajoki A, Tian JL, He HG.. The Effectiveness of Mind-Body Therapies for Women With Gynecological Cancer: A Systematic Review and Meta-analysis. Cancer Nurs. 2023 Apr 24. doi: 10.1097/NCC.0000000000001231. Online ahead of print.. 10.1097/NCC.0000000000001231

  • Yoong SQ, Wang W, Seah ACW, Kumar N, Gan JON, Schmidt LT, Lin Y, Zhang H.. Nursing students' experiences with patient death and palliative and end-of-life care: A systematic review and meta-synthesis. Nurse Educ Pract. 2023 May;69:103625. doi: 10.1016/j.nepr.2023.103625. Epub 2023 Mar 28.. 10.1016/j.nepr.2023.103625

  • Chan X, Tay L, Yap SJ, Wu VX, Klainin-Yobas P.. Effectiveness of Photobiomodulation and Oral Cryotherapy on Oral Mucositis Among Patients Undergoing Chemotherapy Conditioning Prior to Hematological Stem Cell Transplantation. Semin Oncol Nurs. 2023 Jun;39(3):151405. doi: 10.1016/j.soncn.2023.151405. Epub 2023 Mar 21.. 10.1016/j.soncn.2023.151405

  • Teo NR, Siew LED, Ang WHD, Lau Y.. Wearable-Technology-Assisted Interventions for Breast-Cancer Survivors: A Meta-Analysis and Meta-Regression. Semin Oncol Nurs. 2023 Jun;39(3):151403. doi: 10.1016/j.soncn.2023.151403. Epub 2023 Mar 7.. 10.1016/j.soncn.2023.151403

  • Ju X, Bai J, She Y, Zheng R, Xu X, Wang W, Hong J.. Symptom cluster trajectories and sentinel symptoms during the first cycle of chemotherapy in patients with lung cancer. Eur J Oncol Nurs. 2023 Apr;63:102282. doi: 10.1016/j.ejon.2023.102282. Epub 2023 Feb 10.. 10.1016/j.ejon.2023.102282

  • Lee ARYB, Leong I, Lau G, Tan AW, Ho RCM, Ho CSH, Chen MZ.. Depression and anxiety in older adults with cancer: Systematic review and meta-summary of risk, protective and exacerbating factors. Gen Hosp Psychiatry. 2023 Mar-Apr;81:32-42. doi: 10.1016/j.genhosppsych.2023.01.008. Epub 2023 Jan 25.. 10.1016/j.genhosppsych.2023.01.008

  • Thong LT, Chou HS, Chew HSJ, Lau Y.. Diagnostic test accuracy of artificial intelligence-based imaging for lung cancer screening: A systematic review and meta-analysis. Lung Cancer. 2023 Feb;176:4-13. doi: 10.1016/j.lungcan.2022.12.002. Epub 2022 Dec 15.. 10.1016/j.lungcan.2022.12.002

  • Chen HC, Zhu L, Chan WS, Cheng KFK, Vathsala A, He HG.. The effectiveness of a psychoeducational intervention on health outcomes of patients undergoing haemodialysis: A randomized controlled trial. Int J Nurs Pract. 2023 Jun;29(3):e13123. doi: 10.1111/ijn.13123. Epub 2022 Dec 11.. 10.1111/ijn.13123

  • Chen Y, Hou L, Li W, Wang Q, Zhou W, Yang H.. Referral criteria to palliative care for patients with Parkinson's disease: a systematic review. Curr Med Res Opin. 2023 Feb;39(2):267-279. doi: 10.1080/03007995.2022.2146405. Epub 2022 Dec 28.. 10.1080/03007995.2022.2146405

  • Li H, Lyu M, Wang A, Yin Y, Zhang J, Li P.. Social Support and Life Satisfaction in Women With Cervical Cancer: A Serial Multiple Mediation Model. Cancer Nurs. 2024 Jan-Feb 01;47(1):64-71. doi: 10.1097/NCC.0000000000001146. Epub 2022 Dec 11.. 10.1097/NCC.0000000000001146

  • Siew LED, Teo NR, Ang WHD, Lau Y.. Social media-based interventions for patients with cancer: a meta-analysis and meta-regression of randomised controlled trials. J Cancer Surviv. 2023 Dec;17(6):1606-1627. doi: 10.1007/s11764-022-01244-6. Epub 2022 Aug 12.. 10.1007/s11764-022-01244-6

  • Fung JYT, Lim H, Vongsirimas N, Klainin-Yobas P.. Effectiveness of eHealth mindfulness-based interventions on cancer-related symptoms among cancer patients and survivors: A systematic review and meta-analysis. J Telemed Telecare. 2024 Apr;30(3):451-465. doi: 10.1177/1357633X221078490. Epub 2022 Feb 25.. 10.1177/1357633X221078490

  • Wan, S.W., Chen, Y.J.D., Lim, S.H., Chong, C.S., Pikkarainen, M., & He, H.G. (2022). A systematic review and meta-analysis on the effectiveness of web-based psychosocial interventions on patients with colorectal cancer. Journal of Advanced Nursing, 78(7), 1883-1896. doi: 10.1111/jan.15258.

  • Wan, S.W., Chong, C.S., Jee, X.P., Pikkarainen, M., & He, H.G. (2022). Perioperative experiences and needs of patients who undergo colorectal cancer surgery and their family caregivers: a qualitative study. Supportive Care in Cancer, 30(6), 5401-5410. doi: 10.1007/s00520-022-06963-1.

  • Yoong, S. Q., Goh, H. S., & Zhang, H. (2022). Death doulas as supportive companions in end-of-life care: A scoping review. Palliative medicine, 36(5), 795–809. https://doi.org/10.1177/02692163221080659

  • Zhang, L.H., Zhang, L., Gu, W., Miao, R., Jing, X., Zhi, S., Li, H., Ramachandran, H.J., & Wang, W. (2022). The Effects of a Nurse-led couples intervention on marital quality of couples with gynecological cancer: A clinical randomized controlled trial. Gynaecologic Oncology, 165(3):629-636 https://doi.org/10.1016/j.ygyno.2022.03.010

  • Li, J.J., Li, J., Wu, J., Song, Y., Hu, S., Hong, J., & Wang, W. (2021). Symptom clusters change over time in patients with lung cancer during perioperative period. European Journal of Oncology Nursing, 55, 102046. https://doi.org/10.1016/j.ejon.2021.102046

  • Wan, S.W., Chong, C.S., Toh, E.L., Lim, S.H., Loi, T.T., Lew, Y.F.H., Chua, C.H.M., Jee, X.P., Liu, G.Y., Zhu, L.X., Pikkarainen, M., & He, H.G. (2021). A theory-based, multidisciplinary approach to cocreate a patient-centric digital solution to enhance perioperative health outcomes among colorectal cancer patients and their family caregivers: development and evaluation study. Journal of Medical Internet Research, 23(11), e31917. DOI: 10.2196/31917

  • Yiu, H. C., Zang, Y., Chew, J., & Chau, J. (2021). The Influence of Confucianism on the Perceptions and Process of Caring Among Family Caregivers of Persons With Dementia: A Qualitative Study. Journal of transcultural nursing : official journal of the Transcultural Nursing Society, 32(2), 153–160. https://doi.org/10.1177/1043659620905891

  • Pang, Y., Molton, J. S., Ooi, W. T., Paton, N. I., & He, H.-G. (2020). Preliminary effects of a mobile interactive supervised therapy intervention on people living with HIV: pilot randomized controlled trial. JMIR mHealth And uHealth, 8(3), e15702, 11 pages. doi:10.2196/15702

  • Lim, S.H., Chan, W.C.S., Lai, J.H., & He, H.G. (2019). A qualitative evaluation of the STOMA psychosocial intervention programme for colorectal cancer patients with stoma. Journal of Advanced Nursing, 75(1), 108-118. doi: 10.1111/jan.13821

  • Lim, S.H., Chan W.C.S., Chow, A., Zhu L.X., Lai J.H., & He H.G. (2019). Pilot Trial of a STOMA psychosocial intervention programme for colorectal cancer patients with stomas. Journal of Advanced Nursing, 75(6),1338-1346. doi: 10.1111/jan.13973.

Relevant Categories
Cardiovascular Diseases
Mental Health
Metabolic Disorders
Terminal Illness
Learn more

Related Publications

Wan, S.W., Chen, Y.J.D., Lim, S.H., Chong, C.S., Pikkarainen, M., & He, H.G. (2022). A systematic review and meta-analysis on the effectiveness of web-based psychosocial interventions on patients with colorectal cancer. Journal of Advanced Nursing, 78(7), 1883-1896. doi: 10.1111/jan.15258.

Wan, S.W., Chong, C.S., Jee, X.P., Pikkarainen, M., & He, H.G. (2022). Perioperative experiences and needs of patients who undergo colorectal cancer surgery and their family caregivers: a qualitative study. Supportive Care in Cancer, 30(6), 5401-5410. doi: 10.1007/s00520-022-06963-1.

Yoong, S. Q., Goh, H. S., & Zhang, H. (2022). Death doulas as supportive companions in end-of-life care: A scoping review. Palliative medicine, 36(5), 795–809. https://doi.org/10.1177/02692163221080659