Drinking coffee or tea may be beneficial for physical function in ageing   

21 Mar 2025

Duke-NUS and NUS Medicine join forces to launch Systems Metabolomics Centre for precision medicine

In a strategic move for medical research and innovation, Duke-NUS Medical School and the National University of Singapore Yong Loo Lin School of Medicine (NUS Medicine) have launched the Systems Metabolomics Centre (SysMeC), their first-ever joint research centre. This groundbreaking initiative is set to drive cutting-edge metabolomics research, unlocking new ways to detect diseases earlier and tailor treatments for better patient outcomes using precision medicine. By studying cells, tissues and whole organisms using metabolomics – the large-scale study of small molecules known as metabolites – scientists can gain a deeper understanding of how diseases develop and find ways to stop them before they start. From complex metabolic diseases, like diabetes, to single-gene disorders, metabolomics holds a key to shaping precision medicine.

17 Mar 2025

New NUS study: Poor sleep health linked to increased Type 2 diabetes risk in high-risk women with history of gestational diabetes

Underscoring the critical role of sleep in diabetes prevention, investigators from the Global Centre for Asian Women’s Health (GloW) and the Department of Obstetrics and Gynaecology, based at the NUS Yong Loo Lin School of Medicine (NUS Medicine), in collaboration with Harvard T.H. Chan School of Public Health, Brigham and Women's Hospital and Harvard Medical School, has identified a significant link between sleep health and the risk of developing Type 2 diabetes (T2D) among women with a history of gestational diabetes (GDM).

18 Feb 2025

2nd APIC-ADVA Summit: To Drive Discussions on Infectious Diseases and Immunization In the Era of Polycrises

The Asia Pacific Immunization Coalition (APIC) and the Asia Dengue Voice & Action (ADVA), in collaboration with the Centre for Behavioural and Implementation Science Interventions (BISI) at the Yong Loo Lin School of Medicine, National University of Singapore (NUS Medicine), convened the 2nd APIC-ADVA Summit from 11 February to 13 February 2025.

18 Feb 2025

NUS Medicine pioneers ground-breaking technique to deliver drugs directly to the brain

Scientists at the Yong Loo Lin School of Medicine, National University of Singapore (NUS Medicine) have developed a ground-breaking technique to deliver therapeutic molecules directly to the brain, bypassing the blood-brain barrier. Led by Dr Haosheng Shen, lead researcher from the Synthetic Biology Translational Research Programme, NUS Medicine and the NUS Synthetic Biology for Clinical and Technological Innovation (SynCTI) this novel approach utilises a naturally occurring nasal bacterium, Lactobacillus plantarum (Lp), which was genetically engineered to produce therapeutic compounds and release them through a specific nose-to-brain pathway. Their research was published in leading life sciences journal, Cell.

12 Feb 2025

NUS Medicine study: Inability of cells to recycle fats can spell disease

Accumulation of fat molecules is detrimental to the cell. Researchers from the Yong Loo Lin School of Medicine, National University of Singapore (NUS Medicine), have made a breakthrough in understanding how our cells manage to stay healthy by recycling important fat molecules. Their study, published in the journal Proceedings of the National Academy of Sciences (PNAS), reveals how a protein called Spinster homolog 1 (Spns1) helps transport fats out of cell compartments known as lysosomes.

11 Feb 2025

NUS Medicine launches new centre to bolster global pandemic preparedness and response to infectious disease emergencies

NUS Medicine announced the official launch of the Centre for Infectious Disease Emergency Response (CIDER) on 10 February 2025, an innovative initiative aimed at enhancing pandemic preparedness and strengthening responses to infectious disease emergencies. The launch was attended by over 15 ambassadors and other country representatives.

04 Feb 2025

Metastatic cancers: How targeting a protein that fuels treatment-resistant tumours may be key to better outcomes

One of the biggest challenges in cancer treatment is addressing the ability of cancer cells to adapt and become resistant, reducing the effectiveness of therapies over time. While treatments like chemotherapy or targeted therapies may initially shrink tumours, they often lose their effectiveness after a period. This resistance often emerges in metastatic tumours, because cancer cells can evolve in ways that allow them to survive, such as developing new ways to communicate with one another.

28 Jan 2025

Transforming longevity research: AI paves the way for personalised treatments in ageing science

A collaborative study between researchers from the Yong Loo Lin School of Medicine, National University of Singapore (NUS Medicine), and the Institute for Biostatistics and Informatics in Medicine and Ageing Research, Rostock University Medical Center, Germany and published in the leading review journal Ageing Research Reviews investigated how advanced AI tools, like Large Language Models (LLMs), can make it easier to evaluate interventions for ageing and provide personalised recommendations.

23 Jan 2025

NTU Singapore’s TARIPH Centre leads multi-institution research programme with first national research grant for lung health

21 Jan 2025

Shorter, Smarter, Safer: Short-course antibiotics can revolutionise healthcare

Antibiotic overuse is a key driver in the rise of antimicrobial resistance (AMR), a major global health crisis. Researchers from the Yong Loo Lin School of Medicine, National University of Singapore (NUS Medicine) and Duke-NUS Medical School have provided compelling evidence that short-course antibiotic treatments can be a game-changer in tackling ventilator-associated pneumonia (VAP), a serious infection common in critically ill patients.