Drinking coffee or tea may be beneficial for physical function in ageing   

09 Dec 2025

Researchers from NUS Medicine and the Institute of Mental Health detect early brain changes linked to future psychosis development

Researchers at the Yong Loo Lin School of Medicine, National University of Singapore, and NHG Health’s Institute of Mental Health have identified distinct changes in brain network organisation among individuals at clinical high risk for psychosis, providing new insights on how early alterations in brain connectivity may contribute to the development of the disorder.

02 Dec 2025

Short and irregular weekday sleep disrupts glucose regulation even after weekend sleep recovery, NUS Medicine study reveals

Researchers at the Yong Loo Lin School of Medicine, National University of Singapore (NUS Medicine), have found that insufficient weekday sleep significantly disrupts glucose metabolism even when weekend sleep is extended. The study underscores the importance of sleep adequacy and stability and offers new insights into how disrupted sleep patterns may contribute to long-term metabolic risk.

26 Nov 2025

NUS Medicine establishes new mental health scholarship with S$3 million gift from Elaine and Eduardo Saverin Foundation

The Yong Loo Lin School of Medicine, National University of Singapore (NUS Medicine) has received a significant boost with a S$3 million gift from the Elaine and Eduardo Saverin Foundation (EESF).

17 Nov 2025

Discovery in RNA therapy for mutated cancer gene

Two complementary studies led by researchers from the Yong Loo Lin School of Medicine, National University of Singapore (NUS Medicine), have demonstrated a new RNA-based therapeutic strategy that effectively targets one of the most difficult-to-treat cancer genes, Kirsten rat sarcoma viral oncogene homolog (KRAS), while stimulating the body’s immune response to fight tumours. The research was conducted in cell samples and laboratory models, with collaborators from the NUS Institute for Health Innovation and Technology (iHealthtech), Nanyang Technological University (NTU), Agency for Science, Technology and Research (A*STAR), and international partners.

12 Nov 2025

Repurposed antibiotic shows promise against Central Nervous System Tuberculosis in NUS Medicine study

Researchers at the NUS Yong Loo Lin School of Medicine have discovered that combining doxycycline with standard Tuberculosis (TB) treatment may protect the brain from damage caused by excessive immune activity. The research highlights a new approach of suppressing the body’s harmful immune response rather than targeting bacteria alone to minimise adverse effects of standard TB treatment.

10 Nov 2025

NUS Medicine and CHA University to harness artificial intelligence to tackle male infertility, uncovering new approaches to reverse fertility decline

Researchers from the Yong Loo Lin School of Medicine at the National University of Singapore (NUS Medicine) and CHA University in Korea have announced two major advances to extend reproductive longevity at the inaugural NUS-CHA Reproductive Medicine Symposium.

03 Nov 2025

Social interactions help to form lasting memories, NUS Medicine study finds

New findings underscore the importance of regular social interactions in life, shedding light on the strong link between loneliness and sustained social isolation to memory decline and conditions such as dementia, and why social and memory impairments often co-occur in psychiatric disorders.

29 Oct 2025

Silent bug carriers drive E. coli spread in households, NUS Medicine researchers find

Researchers from NUS Medicine have discovered that some people can carry large amounts of a multidrug-resistant strain of Escherichia coli sequence type 131 (E. coli ST131) in their gut for extended periods without showing any symptoms, and can unknowingly pass it on to their household members. The study, published in Nature Communications, is possibly the first in Asia to trace how this antibiotic-resistant bacterium spreads within the community.

27 Oct 2025

Increased risk of developing alcohol addiction linked to gene mutation

Researchers at the Yong Loo Lin School of Medicine, National University of Singapore, have discovered how genetic variation in a single gene, chrna3, can alter alcohol sensitivity. These findings provide new insights into factors that may predispose individuals to alcohol use disorders and could inform personalised treatment plans.

22 Oct 2025

New drug combinations pave the way for personalised leukaemia therapies

Researchers from NUS Medicine have published a landmark review on BH3 mimetics—a new class of drugs that are reshaping the treatment landscape for acute myeloid leukaemia (AML), one of the most aggressive and treatment-resistant blood cancers.