Profile of the month
Chen Kaiwen
PhD
Assistant Professor
Department of Microbiology and Immunology
Affliations:
Email: kaiwen.chen@nus.edu.sg
Research Interest
Programmed cell death, including apoptosis, pyroptosis, and necroptosis, plays essential roles in development, the elimination of infected or transformed cells, and the maintenance of tissue homeostasis. Dysregulation of these pathways has been implicated in a broad range of human diseases. Our laboratory is interested in defining the molecular mechanisms that regulate the activation and termination of programmed cell death, with particular emphasis on infection. We are also interested in how pathogens subvert and modulate cell death pathways and innate immunity, how the tissue microenvironment shapes cell death responses, and how cell death outcomes influence immune regulation.