Appointment(s)
Assistant Dean (Education), Yong Loo Lin School of Medicine, National University of Singapore
Associate Professor, Department of Surgery, National University of Singapore
Degree(s)
Fellow of American College of Surgeons, American College of Cardiology, Washington D.C., United States (22 Mar 2016)
Fellow of Academy of Medicine Singapore, Academy of Medicine Singapore (3 Mar 2010)
Biography
Associate Professor Alfred Kow is a practicing HPB and Liver Transplant surgeon at the National University Hospital Singapore. He is currently the Head of the Hepatobiliary & Pancreatic Surgery at the National University Hospital Singapore. His main area of interest is liver transplantation and minimally invasive HPB surgery. He has pioneered many complex HPB surgeries in Singapore using MIS technique including major laparoscopic hepatectomies, laparoscopic pancreaticoduodenectomy (Whipples’), full laparoscopic ALPPS procedure and laparoscopic liver donor hepatectomy for liver transplantation. He was also the Clinical Director (2017 to 2023) of the MILES program at NUHS (Management and Innovation for Longevity in Elderly Surgical patients), focusing on improving the peri-operative care and outcomes of elderly patients needing surgery in NUHS. In addition, he has been appointed the Vice Chairman of Medical Board (Education) for the National University Hospital Singapore in November 2023. He is also a pioneer in the world in developing mixed reality technology with holographic-guided HPB surgery, including holographic-guided laparoscopic liver resection, holographic-guided donor hepatectomy and holographic-guided laparoscopic Whipples operation.
Onco-fetal Reprogramming of Endothelial Cells Drives Immunosuppressive Macrophages in Hepatocellular Carcinoma. Cell. 183, October 15, 2020: 1–18.
Ankur Sharma, Justine Jia Wen Seow, Charles-Antoine Duterte, Rhea Pai, Alfred Kow Wei Chieh, Ramanuj DasGupta.
World Survey on Minimally Invasive Donor Hepatectomy: A Global Snapshot of Current Practices in 2370 Cases In association with the Expert Consensus and Clinical Guidelines Conference on MIDH held in Seoul, South Korea, September 7, 2019. Transplantation. 2021 Feb 8. PMID: 33586922.
Rotellar F, Ciria R, Wakabayashi G, Shu KS, Cherqui D, WS-MIDH collaborative group (Kow A.W.C.)
Risk factors of peritoneal recurrence and outcome of resected peritoneal recurrence after liver resection in hepatocellular carcinoma: review of 1222 cases of hepatectomy in a tertiary institution. Ann Surg Oncol. 2012 Jul;19(7):2246-55. doi: 10.1245/s10434-012-2260-3. Epub 2012 Mar 9. PMID: 22402812.
Kow AW, Kwon CH, Song S, Shin M, Kim JM, Joh JW.
Clinicopathological factors and long-term outcome comparing between lung and peritoneal metastasectomy after hepatectomy for hepatocellular carcinoma in a tertiary institution. Surgery. 2015 Apr;157(4):645-53. doi: 10.1016/j.surg.2014.07.024. Epub 2014 Nov 4. PMID: 25794626.
Kow AW, Kwon CH, Song S, Kim JM, Joh JW.
The Varying Faces of Gall Bladder Carcinoma. Acta Radiologica. 2012 Jun 1;53(5):494-500. PMID: 22547386.
Lim K.S., Tan C.H., Kow A.W.C.
Is there a role for systematic hepatic pedicle lymphadenectomy in intrahepatic cholangiocarcinoma? A review of 17 years of experience in a tertiary institution. Surgery. 2015 Apr;157(4):666-75. doi: 10.1016/j.surg.2014.11.006. Epub 2015 Feb 12. PMID: 25682172.
Kim DH, Choi DW, Choi SH, Heo JS, Kow AW.
Transplant versus resection in patients with hepatocellular carcinoma. Review. Transl Gastro & Hepatol. May 2019; 4(33). doi: 10.21037/tgh.2019.05.06. eCollection 2019.
Kow A.W.C.
Hepatic metastasis from Colorectal Cancer. Journal of Gastrointestinal Oncology. Dec 2019;10(6):1274-1298.
Kow A.W.C.
Intratumoral immune heterogeneity as a hallmark of tumour evolution and progression in hepatocellular carcinoma. Nature Communication. Nov 2020;12(1):1–13.
Phuong Nguyen, Siming Ma, Cheryl Phua, Neslihan Kaya, Hannah Lai, Chun Jye Lim, Jia Qi Lim, Martin Wasser, Liyun Lai, Wai Leong Tam, Shridhar Iyer, Alfred Kow, Yock Young Dan, Alexander Chung, Pierce Kah-Hoe Chow, Weiwei Zhai, Valerie Chew.
Dynamic phenotypic heterogeneity and the evolution of multiple RNA subtypes in Hepatocellular Carcinoma; the PLANET Study. Natl Sci Rev. 2021 Oct 29;9(3) . doi: 10.1093/nsr/nwab192. eCollection 2022 Mar.
Zhai WW, Lai H, Kow A.W.C, Chow PKH.
