Prof James Hui

Appointment(s)

Clinical Appointments
Head & Senior Consultant, Department of Orthopaedic Surgery, National University Hospital
Senior Consultant, Division of Paediatric Orthopaedic Surgery, Department of Orthopaedic Surgery, National University Hospital
Senior Consultant, Healthy Ageing Programme (Age Better), Alexandra Hospital

Academic Appointments
Ling Chaw Ming Professor in Orthopaedics and Chair, Department of Orthopaedic Surgery, Yong Loo Lin School of Medicine, National University of Singapore
Programme Leader, NUS Tissue Engineering Programme (NUSTEP), Life Science Institute, National University of Singapore

Degree(s)

M.B.B.S., National University of Singapore, Singapore
F.R.C.S. (Edinburgh), Royal College of Surgeons of Edinburgh, United Kingdom
F.A.M.S., Fellow of the Academy of Medicine, Singapore
M.D., National University of Singapore, Singapore

Biography

Prof James Hui specialises in the management of orthopaedic problems in children, as well as general orthopaedics. His special areas of interest are the care, rehabilitation and surgical treatment of musculoskeletal problems occurring in infants and children, such as hip dysplasia and dislocation, foot deformities, spinal deformities, limb length discrepancies and neuromuscular disorders such as Cerebral Palsy, Spina Bifida and Muscular Dystrophy.

Prof Hui completed his medical degree at the National University of Singapore. He subsequently completed his surgical and orthopaedic training at the National University Hospital, Singapore. He is a fellowship-trained paediatric orthopaedic surgeon, having spent a year in Australia on a paediatric orthopaedic fellowship. Prof Hui is actively involved in undergraduate and postgraduate teaching at NUS. He is a member of numerous professional societies including the Paediatric Orthopaedic Society of North America, the Asia Pacific Orthopaedic Association and the Singapore Medical Association. Prof Hui is actively involved in clinical and basic science research.

Selected Publications

Perspective in Achieving Stratified Articular Cartilage Repair Using Zonal Chondrocytes

Tee CA, Han J, Hui JHP, Lee EH, Yang Z

Mesenchymal Stem Cell Exosomes Promote Growth Plate Repair and Reduce Limb-Length Discrepancy in Young Rats

Wong KL, Zhang S, Tan SSH, Cheow YA, Lai RC, Lim SK, Hui JHP, Toh WS

Directionalities of magnetic fields and topographic scaffolds synergise to enhance MSC chondrogenesis

Celik C, Franco-Obregon A, Lee EH, Hui JHP, Yang Z

Pulsed electromagnetic fields potentiate the paracrine function of mesenchymal stem cells for cartilage regeneration

Parate D, Kadir ND, Celik C, Lee EH, Hui JHP, Franco-Obregon A, Yang Z

Equivalent 10-Year Outcomes After Implantation of Autologous Bone Marrow-Derived Mesenchymal Stem Cells Versus Autologous Chondrocyte Implantation for Chondral Defects of the Knee

Teo AQA, Wong KL, Shen L, Lim JY, Toh WS, Lee EH, Hui JHP

MSC exosomes mediate cartilage repair by enhancing proliferation, attenuating apoptosis and modulating immune reactivity

Co-authorsZhang S, Chuah SJ, Lai RC, Hui JHP, Lim SK, Toh WS

Exosomes derived from human embryonic mesenchymal stem cells promote osteochondral regeneration

Zhang S, Chu WC, Lai RC, Lim SK, Hui JHP, Toh WS

Substrate topography determines the fate of chondrogenesis from human mesenchymal stem cells resulting in specific cartilage phenotype formation

Wu Y-N, Law JBK, He AY, Low HY, Hui JHP, Lim CT, Yang Z, Lee EH

Affinity-selected heparan sulfate for bone repair

Murali S, Rai B, Dombrowski C, Lee JLJ, Lim ZXH, Bramono DS, Ling L, Bell T, Hinkley S, Nathan SS, Hui JH, Wong HK, Nurcombe V, Cool SM

Hyaluronic acid-based hydrogels functionalized with heparin that support controlled release of bioactive BMP-2

Bhakta G, Rai B, Lim ZXH, Hui JH, Stein GS, van Wijnen AJ, Nurcombe V, Prestwich GD, Cool SM

The potential of human fetal mesenchymal stem cells for off-the-shelf bone tissue engineering application

Zhang Z-Y, Teoh S-H, Hui JHP, Fisk NM, Choolani M, Chan JKY

Biomimetic hydrogels for chondrogenic differentiation of human mesenchymal stem cells to neocartilage

Liu SQ, Tian Q, Hedrick JL, Hui JHP, Ee PLR, Yang YY

Autologous Bone Marrow-Derived Mesenchymal Stem Cells Versus Autologous Chondrocyte Implantation An Observational Cohort Study

Nejadnik H, Hui JH, Choong EPF, Tai B-C, Lee EH

The influence of fibrin based hydrogels on the chondrogenic differentiation of human bone marrow stromal cells

Ho STB, Cool SM, Hui JH, Hutmacher DW

Cartilaginous ECM component-modification of the micro-bead culture system for chondrogenic differentiation of mesenchymal stem cells

Wu Y-N, Yang Z, Hui JHP, Ouyang H-W, Lee EH