Appointment(s)
Associate Professor, Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore
Head of Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore
Director, Phase II Undergraduate Medical Curriculum, Yong Loo Lin School of Medicine, National University of Singapore
Director, Neuroscience and Metabolic Phenotyping Core, National University of Singapore
Degree(s)
BSc (Hons), PhD, MMHPE
Biography
Associate Professor Gavin Dawe earned his PhD in Pharmacology from the Institute of Psychiatry at King’s College London, part of the University of London, UK. Following postdoctoral research at the same institute, he ventured into the biotechnology and pharmaceutical industry, holding positions at ReNeuron Limited and Eli Lilly and Company. He later joined the National University of Singapore (NUS), where he currently serves as an Associate Professor and Head of Department in the Department of Pharmacology at the Yong Loo Lin School of Medicine (NUS Medicine). Additionally, he is a principal investigator with affiliations to the Neurobiology Programme at the Life Sciences Institute and the Healthy Longevity and Precision Medicine Translational Research Programmes at Yong Loo Lin School of Medicine. Dawe’s laboratory focuses on peptide neuropharmacology in the context of ageing, neuroscience, and mental health disorders, employing a range of methods, including systems neurobiology, behavioural neuroscience, electrophysiology, and optogenetics. His contributions to the field have been recognized with several awards, such as the Asian College of Neuropsychopharmacology (AsCNP) Basic Scientist Award in 2023, the Singapore Neuroscience Association Distinguished Neuroscientist Award in 2017, and the GlaxoSmithKline (GSK) Academic Centre of Excellence Research Award in 2010. A/Prof Dawe also directs the NUS Neuroscience and Metabolic Phenotyping Core, offering behavioural and metabolic phenotyping facilities and services to the wider NUS and Singapore research community. Committed to advancing medical and health professions education, he obtained a Master’s degree in Medical and Health Professions Education (MMHPE) from Eastern Virginia Medical School in 2019. He oversees the Phase II Undergraduate Medical Curriculum at NUS Medicine and is keen on integrating digitalization and artificial intelligence into medical education.
Test, rinse, repeat: A review of carryover effects in rodent behavioral assays
Cnops, V., Iyer, V. R., Parathy, N., Wong, P., & Dawe, G. S
Mechanisms of biased agonism by Gαi/o-biased stapled peptide agonists of the relaxin-3 receptor
Jayakody, T., Inoue, A., Kannan, S., Nakamura, G., Kawakami, K., Mendis, K., Nguyen, T. B., Li, J., Herr, D. R., Verma, C. S., & Dawe, G. S.
Mechanisms of Action and Persistent Neuroplasticity by Drugs of Abuse
Korpi, E. R., den Hollander, B., Farooq, U., Vashchinkina, E., Rajkumar, R., Nutt, D. J., Hyytiä, P., & Dawe, G. S.
Relaxin' the brain: a case for targeting the nucleus incertus network and relaxin-3/RXFP3 system in neuropsychiatric disorders
Kumar, J. R., Rajkumar, R., Jayakody, T., Marwari, S., Hong, J. M., Ma, S., Gundlach, A. L., Lai, M. K. P., & Dawe, G. S.
Nucleus incertus contributes to an anxiogenic effect of buspirone in rats: Involvement of 5-HT1A receptors
Kumar, J. R., Rajkumar, R., Lee, L. C., & Dawe, G. S.
Hope for vascular cognitive impairment: Ac-YVAD-cmk as a novel treatment against white matter rarefaction
Lim, Y. A., Tan, L. S., Lee, W. T., Sim, W. L., Lv, Y., Takakuni, M., Saito, S., Ihara, M., Arumugam, T. V., Chen, C., Wong, F. W., & Dawe, G. S.
APP upregulation contributes to retinal ganglion cell degeneration via JNK3
Liu, C., Zhang, C. W., Zhou, Y., Wong, W. Q., Lee, L. C., Ong, W. Y., Yoon, S. O., Hong, W., Fu, X. Y., Soong, T. W., Koo, E. H., Stanton, L. W., Lim, K. L., Xiao, Z. C., & Dawe, G. S.
A TAG1-APP signalling pathway through Fe65 negatively modulates neurogenesis
Ma, Q. H., Futagawa, T., Yang, W. L., Jiang, X. D., Zeng, L., Takeda, Y., Xu, R. X., Bagnard, D., Schachner, M., Furley, A. J., Karagogeos, D., Watanabe, K., Dawe, G. S., & Xiao, Z. C.
Intranasal administration of a stapled relaxin-3 mimetic has anxiolytic- and antidepressant-like activity in rats
Marwari, S., Poulsen, A., Shih, N., Lakshminarayanan, R., Kini, R. M., Johannes, C. W., Dymock, B. W., & Dawe, G. S.
The duration of lithium use and biological ageing: telomere length, frailty, metabolomic age and all-cause mortality
Mutz, J., Wong, W. L. E., Powell, T. R., Young, A. H., Dawe, G. S., & Lewis, C. M.
Fetal microchimerism in the maternal mouse brain: A novel population of fetal progenitor or stem cells able to cross the blood-brain barrier?
Tan, X. W., Liao, H., Sun, L., Okabe, M., Xiao, Z. C., & Dawe, G. S.
Investigating the role of the relaxin-3/RXFP3 system in neuropsychiatric disorders and metabolic phenotypes: A candidate gene approach
Wong, W. L. E., Arathimos, R., Lewis, C. M., Young, A. H., & Dawe, G. S.
The Effects of CYP2C19 Genotype on Proxies of SSRI Antidepressant Response in the UK Biobank
Wong, W. L. E., Fabbri, C., Laplace, B., Li, D., van Westrhenen, R., Lewis, C. M., Dawe, G. S., & Young, A. H.
