Appointment(s)
Associate Professor, Department of Physiology, National University of Singapore
Assistant Dean (Education), National University of Singapore
Principal Investigator, NUS Centre for Cancer Research Translational Research Programme (N2CR)
Degree(s)
Organizational Leadership (Online Course), Harvard Business School Online, January 2024 – March 2024
Master’s Degree, Health Professions Education, Maastricht University, 2016 – 2018
Certificate in Health Professions Education, NUS Yong Loo Lin School of Medicine, 2015 – 2016
Doctor of Philosophy (Ph.D.), Cell and Molecular Biology / Cancer Biology, National University of Singapore, 2005 – 2009
Bachelor’s Degree, Life Sciences (Biomedical Science), National University of Singapore, 2001 – 2005
Biography
Zhi Xiong is Assistant Dean (Education) of NUS Medicine. He is Chairperson of Asia-Pacific Biomedical Science Educators Association and Board Member of International Association of Medical Science Educators. Zhi Xiong is Principal Investigator of Neurodevelopment and Cancer Laboratory at NUS Centre for Cancer Research and Joint Scientist of KK Women’s and Children’s Hospital. Involved in the education of medical, dental, pharmacy and life sciences students, Zhi Xiong is exploring ways to broaden health professions education and promote transdisciplinary learning with specific interests in the role of medical sciences in health professions practice, faculty development, student affairs and medical education technology.
Pro-metastatic and mesenchymal gene expression signatures characterize circulating tumor cells of neuroblastoma patients with bone marrow metastases and relapse. Frontiers in oncology, 12, 939460.
Loh, A., Angelina, C., Wong, M. K., Tan, S. H., Sukhatme, S. A., Yeo, T., Lim, S. B., Lee, Y. T., Soh, S. Y., Leung, W., Chang, K., Chua, Y. W., Alkaff, S., Lim, T., Lim, C. T., & Chen, Z. X. (2022).
Integrated Genomic Profiling and Drug Screening of Patient-Derived Cultures Identifies Individualized Copy Number-Dependent Susceptibilities Involving PI3K Pathway and 17q Genes in Neuroblastoma. Front Oncol, 11, 709525.
Wong, R. L. Y., Wong, M. R. E., Kuick, C. H., Saffari, S. E., . . . Chen, Z. X., Iyer, P., Tan, E. E. K., Soh, S. Y., Iyer, N. G., Fan, Q., and Loh, A. H. P. (2021).
KIF1Bbeta increases ROS to mediate apoptosis and reinforces its protein expression through O 2(-) in a positive feedback mechanism in neuroblastoma. Sci Rep, 7(1), 16867.
Angelina, C., Tan, I. S. Y., Choo, Z., Lee, O. Z. J., Pervaiz, S., and Chen, Z. X. (2017).
Neuroblastoma patient-derived cultures are enriched for a mesenchymal gene signature and reflect individual drug response. Cancer Sci, 111(10), 3780-3792.
Hee, E., Wong, M. K., Tan, S. H., Choo, Z., . . . Chen, Z., Chang, K. T. E., and Loh, A. H. P. (2020).
Destined to Die: Apoptosis and Pediatric Cancers. Cancers, 11(11), 1623.
Choo, Z., Loh, A. H. P., and Chen, Z. X. (2019).
Mutations of 1p genes do not consistently abrogate tumor suppressor functions in 1p-intact neuroblastoma. BMC cancer, 22(1), 717.
Kuick, C. H., Tan, J. Y., Jasmine, D., Sumanty, T., Ng, A., Venkatesh, B., Chen, H., Loh, E., Jain, S., Seow, W. Y., Ng, E., Lian, D., Soh, S. Y., Chang, K., Chen, Z. X., & Loh, A. (2022).
RNA helicase A is a downstream mediator of KIF1Bbeta tumor-suppressor function in neuroblastoma. Cancer Discov, 4(4), 434-451.
Chen, Z. X., Wallis, K., Fell, S. M., Sobrado, V. R., Hemmer, M. C., Ramskold, D., . . . Schlisio, S. (2014).
The 1p36 Tumor Suppressor KIF 1Bbeta Is Required for Calcineurin Activation, Controlling Mitochondrial Fission and Apoptosis. Dev Cell, 36(2), 164-178.
Li, S., Fell, S. M., Surova, O., Smedler, E., Wallis, K., Chen, Z. X., . . . Schlisio, S. (2016).
Wanted DEAD/H or Alive: Helicases Winding Up in Cancers. J Natl Cancer Inst, 109(6). #co-first authors
Cai, W., Xiong Chen, Z.#, Rane, G., Satendra Singh, S., Choo, Z., Wang, C., . . . Prem Kumar, A. (2017).
Inter-related issues that impact motivation in biomedical sciences graduate education. TAPS, 5(3), 10-19. doi.org/10.29060/TAPS.2020-5-3/OA2113
Chen, Z. X., Lee, S. S., Samarasekera, D. D., and Stalmeijer, R. (2020).
Patients’ and healthcare professionals’ perspectives towards technology-assisted diabetes self-management education. A qualitative systematic review. PLoS One, 15(8), doi: 10.1371/journal.pone.0237647
Jain, S. R., Sui, Y., Ng, C. H., Chen, Z. X., Goh, L. H., and Shorey, S. (2020).
Is ChatGPT ‘ready’ to be a learning tool for medical undergraduates and will it perform equally in different subjects? – Comparative study of ChatGPT performance in tutorial and case-based learning questions in Physiology and Biochemistry. Med Teach, Jan 31:1-7. doi: 10.1080/0142159X.2024.2308779. Online ahead of print.
Luke, W. A. N. V., Lee, S. C., Ban, K. H. K., Wong, A. H. P., Chen, Z. X., Lee, S. S., Taneja, R., Samarasekera, D. D., Yap, C. T. S. M. (2024).
Enhancing the use of peer review and student feedback to evaluate educators in early years of health professions education: insights from a medical school. Singapore Med J, May 5. doi: 10.11622/smedj.2022051. Online ahead of print.
Lee, S. S., Indran, I. R., Yap, C. T., Samarasekera, D. D., Wong, S. J. Y., and Chen, Z. X. (2022).
Curriculum Organisation: ‘Why Can’t I Just Teach What I Know?’. In D. D. Samarasekera (Ed.) and M. C. E. Gwee (Ed.), Educate, Train and Transform: Toolkit on Medical and Health Professions Education (pp. 15-32). Hackensack, NJ: World Scientific.
Gwee, M. C. E., Samarasekera, D. D., and Chen, Z. X. (2021).
