Healthy Aging

Older adulthood introduces challenges involving declining health and physical function. While promoting wellness in older adults is an important aspect to healthy ageing, it might not be achievable due to misperceptions and lack of knowledge.

Therefore, this theme seeks to provide evidence-based information that distinguishes between deterioration due to normal biological ageing process and deterioration due to diseases, with the aim of generating new knowledge and developing interventions to establish the relationship between ageing and wellness.

Core Members: Dr Betsy SEAH, Dr Rosalind SIAH, Dr Vivien WU

Publications

  • Ong CH, Pham BL, Levasseur M, Tan GR, Seah B.. Sex and gender differences in social participation among community-dwelling older adults: a systematic review. Front Public Health. 2024 Apr 12;12:1335692. doi: 10.3389/fpubh.2024.1335692. eCollection 2024.. 10.3389/fpubh.2024.1335692

  • Ng YX, Cheng LJ, Quek YY, Yu R, Wu XV.. The measurement properties and feasibility of FRAIL scale in older adults: A systematic review and meta-analysis. Ageing Res Rev. 2024 Mar;95:102243. doi: 10.1016/j.arr.2024.102243. Epub 2024 Feb 21.. 10.1016/j.arr.2024.102243

  • Yoong SQ, Wu VX, Chen C, Lee PY, Wee KSL, Teo J, Chua MCH, Jiang Y.. Dance Exergames for Older Adults: A Systematic Review and Meta-Analysis With Narrative Synthesis. J Gerontol A Biol Sci Med Sci. 2024 Apr 1;79(4):glae035. doi: 10.1093/gerona/glae035.. 10.1093/gerona/glae035

  • Yoong SQ, Wu VX, Jiang Y.. Experiences of older adults participating in dance exergames: A systematic review and meta-synthesis. Int J Nurs Stud. 2024 Apr;152:104696. doi: 10.1016/j.ijnurstu.2024.104696. Epub 2024 Jan 15.. 10.1016/j.ijnurstu.2024.104696

  • Zhang J, Tam WWS, Hounsri K, Kusuyama J, Wu VX.. Response to Letter to the Editor on "Effectiveness of Combined Aerobic and Resistance Exercise on Cognition, Metabolic Health, Physical Function, and Health-Related Quality of Life in Middle-Aged and Older Adults With Type 2 Diabetes Mellitus: A Systematic Review and Meta-analysis". Arch Phys Med Rehabil. 2024 May;105(5):1023-1024. doi: 10.1016/j.apmr.2024.01.001. Epub 2024 Jan 6.. 10.1016/j.apmr.2024.01.001

  • Tang A, Ho R, Yu R, Huynh T, Luong S, Tam W, Resnick B.. Editorial: Can artificial intelligence help us overcome challenges in geriatrics?. Geriatr Nurs. 2023 Jul-Aug;52:A1-A2. doi: 10.1016/j.gerinurse.2023.06.007. Epub 2023 Jun 27.. 10.1016/j.gerinurse.2023.06.007

  • Zhang J, Tam WWS, Hounsri K, Kusuyama J, Wu VX.. Effectiveness of Combined Aerobic and Resistance Exercise on Cognition, Metabolic Health, Physical Function, and Health-related Quality of Life in Middle-aged and Older Adults With Type 2 Diabetes Mellitus: A Systematic Review and Meta-analysis. Arch Phys Med Rehabil. 2023 Oct 22:S0003-9993(23)00591-9. doi: 10.1016/j.apmr.2023.10.005. Online ahead of print.. 10.1016/j.apmr.2023.10.005

  • Quek YY, Cheng LJ, Ng YX, Hey HWD, Wu XV.. Effectiveness of anthocyanin-rich foods on bone remodeling biomarkers of middle-aged and older adults at risk of osteoporosis: a systematic review, meta-analysis, and meta-regression. Nutr Rev. 2023 Oct 5:nuad121. doi: 10.1093/nutrit/nuad121. Online ahead of print.. 10.1093/nutrit/nuad121

  • Hong XL, Cheng LJ, Feng RC, Goh J, Gyanwali B, Itoh S, Tam WSW, Wu XV.. Effect of physio-cognitive dual-task training on cognition in pre-ageing and older adults with neurocognitive disorders: A meta-analysis and meta-regression of randomized controlled trial. Arch Gerontol Geriatr. 2024 Jan;116:105161. doi: 10.1016/j.archger.2023.105161. Epub 2023 Aug 19.. 10.1016/j.archger.2023.105161

  • Chua CMS, Chua JYX, Shorey S.. Effectiveness of home-based interventions in improving loneliness and social connectedness among older adults: a systematic review and meta-analysis. Aging Ment Health. 2024 Jan-Feb;28(1):1-10. doi: 10.1080/13607863.2023.2237919. Epub 2023 Jul 19.. 10.1080/13607863.2023.2237919

  • Wu VX, Yap XY, Tam WSW, Goh J, Mok WYJ, Ramazanu S.. Qualitative inquiry of a community dance program for older adults in Singapore. Nurs Health Sci. 2023 Sep;25(3):341-353. doi: 10.1111/nhs.13032. Epub 2023 Jul 11.. 10.1111/nhs.13032

  • Sam RY, Lau YFP, Lau Y, Lau ST.. Types, functions and mechanisms of robot-assisted intervention for fall prevention: A systematic scoping review. Arch Gerontol Geriatr. 2023 Dec;115:105117. doi: 10.1016/j.archger.2023.105117. Epub 2023 Jul 4.. 10.1016/j.archger.2023.105117

  • Rashid NLA, Leow Y, Klainin-Yobas P, Itoh S, Wu VX.. The effectiveness of a therapeutic robot, 'Paro', on behavioural and psychological symptoms, medication use, total sleep time and sociability in older adults with dementia: A systematic review and meta-analysis. Int J Nurs Stud. 2023 Sep;145:104530. doi: 10.1016/j.ijnurstu.2023.104530. Epub 2023 May 19.. 10.1016/j.ijnurstu.2023.104530

  • Soh YY, Zhang H, Toh JJY, Li X, Wu XV.. The effectiveness of tele-transitions of care interventions in high-risk older adults: A systematic review and meta-analysis. Int J Nurs Stud. 2023 Mar;139:104428. doi: 10.1016/j.ijnurstu.2022.104428. Epub 2022 Dec 15.. 10.1016/j.ijnurstu.2022.104428

  • Teo RH, Cheng WH, Cheng LJ, Lau Y, Lau ST.. Global prevalence of social isolation among community-dwelling older adults: A systematic review and meta-analysis. Arch Gerontol Geriatr. 2023 Apr;107:104904. doi: 10.1016/j.archger.2022.104904. Epub 2022 Dec 16.. 10.1016/j.archger.2022.104904

  • Yu M, Wang W, Gu L, Ramachandran HJ.. Perspectives and experiences of living with self-neglect among older adults: A systematic review and meta-synthesis. J Nurs Scholarsh. 2023 Jul;55(4):771-781. doi: 10.1111/jnu.12854. Epub 2022 Dec 9.. 10.1111/jnu.12854

  • Toh JJY, Zhang H, Soh YY, Zhang Z, Wu XV.. Prevalence and health outcomes of polypharmacy and hyperpolypharmacy in older adults with frailty: A systematic review and meta-analysis. Ageing Res Rev. 2023 Jan;83:101811. doi: 10.1016/j.arr.2022.101811. Epub 2022 Nov 29.. 10.1016/j.arr.2022.101811

  • Li Y, Lyu L, Fan X, Xu L, Zhao R, Jiang Y, Seo J, Li C, Song R.. Translation and Linguistic Validation of the Assessment of Physical Activity in Frail Older People into Simplified Chinese Using Cognitive Interviewing Methodology. J Aging Phys Act. 2022 Oct 19;31(3):383-390. doi: 10.1123/japa.2022-0100. Print 2023 Jun 1.. 10.1123/japa.2022-0100

  • Feng RC, Dong YH, Hong XL, Su Y, Wu XV.. Effects of anthocyanin-rich supplementation on cognition of the cognitively healthy middle-aged and older adults: a systematic review and meta-analysis of randomized controlled trials. Nutr Rev. 2023 Feb 10;81(3):287-303. doi: 10.1093/nutrit/nuac055.. 10.1093/nutrit/nuac055

  • Chow EKM, Seah B, Chan JJY, Wang W.. Salutogenic-based interventions among community-dwelling older adults: a systematic review and meta-analysis. Health Promot Int. 2023 Jun 1;38(3):daac007. doi: 10.1093/heapro/daac007.. 10.1093/heapro/daac007

  • Feng, R.C., Dong, Y., Hong, X.L., SU, Y., Wu, X.V. (2022). Effects of Anthocyanin-Rich Supplementation on Cognition of the Cognitively Healthy Middle-aged and Older Adults: A Systematic Review and Meta-analysis of Randomized Controlled Trials, Nutrition Reviews.

  • Xing H, Lu, J., Yoong, S.Q., Tan, Y.Q., Joji Kusuyama, J., Wu, X. V. (2022). Effect of Aerobic and Resistant Exercise Intervention on Inflammaging of Type 2 Diabetes Mellitus in Middle-aged and Older Adults: A Systematic Review and Meta-analysis. Journal of the American Medical Directors Association, PMID: 35183493. DOI: 10.1016/j.jamda.2022.01.055

  • Yu, M., Ramachandran, H.J., Qian, M., Shi, Y., Gu, L., & Wang, W. (2022). Understanding professionals’ perspectives and experiences of elder self-neglect: a systematic review and meta-synthesis of qualitative studies. Journal of Nursing Scholarship, 54(1), 24-30. 00, 1-7. https://doi-org.libproxy1.nus.edu.sg/10.1111/jnu.12710

  • Chin, W.J., Ho, S.Y.L., Ramazanu, S., Itoh, S., Klainin-Yobas, P., Wu, X.V. (2021). Effectiveness of Technology-based Interventions on Psychological Morbidities, Quality of Life for Informal Caregivers of Stroke Survivors: A Systematic Review and Meta-analysis. Journal of Advanced Nursing, DOI: https://doi.org/10.1111/jan.15130

  • Leong, K.S., Klainin-Yobas, P., Fong, S.D., Wu, X.V. (2021). Older Adults’ Perspective of Intergenerational Programme at Senior Day Care Centre in Singapore: A Descriptive Qualitative Study, Health & Social Care in the Community. https://doi.org/10.1111/hsc.13432.

  • Seah, B., Espnes, G. A., Ang, E., Lim, J. Y., Kowitlawakul, Y., & Wang, W. (2021). Achieving healthy ageing through the perspective of sense of coherence among senior-only households: a qualitative study. Aging & mental health, 25(5), 936–945. https://doi.org/10.1080/13607863.2020.1725805

  • Tam, W., Poon, S. N., Mahendran, R., Kua, E. H., Wu, X. V. (2021). The Effectiveness of Reminiscence-based Intervention on Improving Psychological Well-being in Cognitively Intact Older Adults: A Systematic Review and Meta-analysis, Int J Nurs Stud. 114:103847. https://doi.org/10.1016/j.ijnurstu.2020.103847.

  • Wu, X. V.*, Chi, Y., Lee, J.K., Goh, H.S., Chen, D.Y.M., Haugan, G., Chao, F.F.T., Klainin-Yobas, P. (2021). The effect of dance interventions on cognition, neuroplasticity, physical function, depression, and quality of life for older adults with mild cognitive impairment: A systematic review and meta-analysis, Int J Nurs Stud. DOI: 10.1016/j.ijnurstu.2021.104025 [IF: 6.847]

  • Yap, J.M., Tantono, N., Wu, X.V., & Klainin-Yobas, P. (2021). Effectiveness of Technology-based Psychosocial Interventions on Diabetes Distress and Health-relevant outcomes of Type 2 Diabetes Mellitus: A Systematic Review and Meta-analysis. Journal of Telemedicine and Telecare. DOI: 10.1177/1357633X211058329

  • Yu, M., Gu, L., Shi, Y., & Wang, W. (2021). A systematic review of self-neglect and its risk factors among community-dwelling older adults. Aging & Mental Health, 25(12), 2179-2190. https://doi-org.libproxy1.nus.edu.sg/10.1080/13607863.2020.1821168

  • Choo, Y. T., Jiang, Y., Hong, J., & Wang, W. (2020). Effectiveness of Tai Chi on quality of life, depressive symptoms and physical function among community-dwelling older adults with chronic disease: A systematic review and meta-analysis. International Journal of Nursing Studies, 111, 103737. https://doi.org/10.1016/j.ijnurstu.2020.103737

  • Chow, G., Gan, J.K.E., Chan, J.K.Y., Wu, X.V., Klainin-Yobas, P. (2020). Effectiveness of psychosocial interventions among older adults with mild cognitive impairment: a systematic review and meta-analysis. Aging Ment Health. 17:1-12. doi: 10.1080/13607863.2020.1839861.

  • Seah, B., Espnes, G. A., Ang, E. N. K., Lim, J. Y., Kowitlawakul, Y., & Wang, W. (2020). Supporting the mobilization of health assets among older community dwellers residing in senior-only households in Singapore: a qualitative study. BMC Geriatrics 20 (411). https://doi.org/10.1186/s12877-020-01810-6

  • Chan, D. Y. M. Wu, X. V., Chan, E. Y., & Goh, Y. S. (2019). Nurse-Led Tele-coaching on the Modifiable Cardiovascular risk factors in people with Type 2 diabetes mellitus: A systematic review and Meta-analysis. Worldviews on Evidence-Based Nursing. DOI:10.1111/wvn.12409

  • Chua, C.H.M., Jiang, Y., Lim, D.S., Wu, V.X., Wang, W. (2019). Effectiveness of cognitive behaviour therapy-based multicomponent interventions on fear of falling among community-dwelling older adults: A systematic review and meta-analysis. Journal of Advanced Nursing, 75(12), 3299-3315. https://doi-org.libproxy1.nus.edu.sg/10.1111/jan.14150

  • Gouw, V.X.H., Jiang, Y., Seah, B., He, H-G., Hong, J., & Wang, W. (2019). Effectiveness of internal Qigong on quality of life, depressive symptoms and self-efficacy among community-dwelling older adults with chronic diseases: A systematic review and meta-analysis. International Journal of Nursing Studies, 99, 1-9. 103378. https://doi.org/10.1016/j.ijnurstu.2019.06.009

  • Seah, B., Kowitlawakul, Y., Jiang, Y., Ang, E., Chokkanathan, S., & Wang, W. (2019). A review on healthy ageing interventions addressing physical, mental and social health of independent community-dwelling older adults. Geriatric nursing, 40(1), 37–50. https://doi.org/10.1016/j.gerinurse.2018.06.002

Relevant Categories
Community Care
End-of-life Care
Healthy Aging
Learn more

Related Publications

Grant - Wu, X.V. (PI) 2021-2024. JSPS-NUS Joint Research Grant. Translational research to establish healthy longevity program using exercise memory through aerobic and resistant exercise intervention in middle-age with Type 2 Diabetes. $76,000, Japan Society for the Promotion of Science and National University of Singapore.

Grant - Wu, X.V. (PI) 2021-2022. Mental Health Fund. Community Dance Program for Older Adults . $49,666, Mind the Gap 200.

Grant - Seah, B. (PI) 2010-2021. Singapore Population HEalth ImpRovement Centre (SPHERiC) Fellowship Programme. Salutogenic Healthy Ageing Programme Embracement for senior-only households, SG$10,000, Singapore Population HEalth ImpRovement Centre.

Grant - Wu, X.V. (PI) 2020-2021. Interstellar Initiative Fund, The effects of Exercise in the Middle Ages on Metabolic Health in Older Adults. $37,8000, New York Academy of Sciences and Japan Agency for Medical Research and Development.

Grant - Wu, X.V. (PI) 2020-2021. Mitsui Sumitomo Insurance Welfare Foundation Research Grant, Development of an Intelligent Advisory System for Safe and Active Aging . $9,964, Mitsui Sumitomo Insurance Welfare Foundation.