Recognizing and Responding to Clinical Deterioration

  1. Liaw SY, Rethans JJ, Scherpbier A, Piyanee KY. Rescuing A Patient In Deteriorating Situations (RAPIDS): a simulation-based educational program on recognizing, responding and reporting of physiological signs of deterioration. Resuscitation. 2011 Sep;82(9):1224-30. doi: 10.1016/j.resuscitation.2011.04.014

  2. Liaw SY, Scherpbier A, Klainin-Yobas P, Rethans JJ. Rescuing A Patient In Deteriorating Situations (RAPIDS): an evaluation tool for assessing simulation performance on clinical deterioration. Resuscitation. 2011 Nov;82(11):1434-9. doi: 10.1016/j.resuscitation.2011.06.008

  3. Liaw SY, Chan SW, Scherpbier A, Rethans JJ, Pua GG. Recognizing, responding to and reporting patient deterioration: transferring simulation learning to patient care settings. Resuscitation. 2012 Mar;83(3):395-8. doi: 10.1016/j.resuscitation.2011.08.021

  4. Ignacio J, Dolmans D, Scherpbier A, Rethans JJ, Chan SW, Liaw SY. Stress and anxiety management strategies in health professions' simulation training: a review of the literature. BMJ Simul Technol Enhanc Learn. 2016;2(2):42 - 46. doi:10.1136/bmjstel-2015-000097

  5. Ignacio J, Dolmans D, Scherpbier A, Rethans JJ, Chan S, Liaw SY. Comparison of standardized patients with high-fidelity simulators for managing stress and improving performance in clinical deterioration: a mixed methods study. Nurse Educ Today. 2015 Dec;35(12):1161-8. doi: 10.1016/j.nedt.2015.05.009

  6. Ignacio J, Dolmans D, Scherpbier A, Rethans JJ, Lopez V, Liaw SY. Development, implementation, and evaluation of a mental rehearsal strategy to improve clinical performance and reduce stress: a mixed methods study. Nurse Educ Today. 2016 Feb;37:27-32. doi: 10.1016/j.nedt.2015.11.002

  7. Ignacio J, Scherpbier A, Dolmans D, Rethans JJ, Liaw SY. Mental rehearsal strategy for stress management and performance in simulations. Clin Simul Nurs. 2017 Jul;13(7):295-302. doi: 10.1016/j.ecns.2017.04.005

  8. Liaw SY, Chan SW, Chen FG, Hooi SC, Siau C. Comparison of virtual patient simulation with mannequin-based simulation for improving clinical performances in assessing and managing clinical deterioration: randomized controlled trial. J Med Internet Res. 2014 Sep 17;16(9):e214. doi: 10.2196/jmir.3322

  9. Liaw SY, Wong LF, Chan SW, Ho JT, Mordiffi SZ, Ang SB, et al. Designing and evaluating an interactive multimedia web-based simulation for developing nurses' competencies in acute nursing care: randomized controlled trial. J Med Internet Res. 2015 Jan 12;17(1):e5. doi: 10.2196/jmir.3853

  10. Liaw SY, Wong LF, Ang SB, Ho JT, Siau C, Ang EN. Strengthening the afferent limb of rapid response systems: an educational intervention using web-based learning for early recognition and responding to deteriorating patients. BMJ Qual Saf. 2016 Jun;25(6):448-56. doi: 10.1136/bmjqs-2015-004073

  11. Lin PY, Chua WL, Mok WQ, Liaw SY. Using a case-based animation on physiological compensatory mechanism to remediate nurses' misconceptions about changes in patient vital signs. J Clin Nurs. 2016 Feb;25(3-4):566-8. doi: 10.1111/jocn.13082

  12. Liaw SY, Chng DY, Wong LF, Ho JT, Mordiffi SZ, Cooper S, et al. The impact of a web-based educational program on the recognition and management of deteriorating patients. J Clin Nurs. 2017 Dec;26(23-24):4848-4856. doi: 10.1111/jocn.13955

  13. Liaw SY, Wong LF, Lim EY, Ang SB, Mujumdar S, Ho JT, et al. Effectiveness of a web-Based simulation in improving nurses' workplace practice with deteriorating ward patients: a pre- and postintervention study. J Med Internet Res. 2016 Feb 19;18(2):e37. doi: 10.2196/jmir.5294

  14. Liaw SY, Lim EY, Wong LF, Ho JT, Mordiffi SZ, Ang SB, et al. The effect of a web-based educational program on nursing practice in recognising and responding to deteriorating ward patients: a qualitative evaluation study. Collegian. 2017 Oct;24(5):455-461. doi: 10.1016/j.colegn.2016.09.008

  15. Liaw SY, Sutini, Chua WL, Tan JZ, Levett-Jones T, Ashokka B, et al. Desktop virtual reality versus face-to-face simulation for team-training on stress levels and performance in clinical deterioration: a randomized controlled trial. J Gen Intern Med. 2022. doi: 10.1007/s11606-022-07557-7

  16. Chua WL, Ooi SL, Chan GW, Lau TC, Liaw SY. The effect of a sepsis interprofessional education using virtual patient telesimulation on sepsis team care in clinical practice: mixed-methods study. J Med Internet Res. 2022;24(4):e35058. doi: 10.2196/35058

  17. Liaw SY, Rashasegaran A, Wong LF, Deneen CC, Cooper S, Levett-Jones T, et al. Development and psychometric testing of a Clinical Reasoning Evaluation Simulation Tool (CREST) for assessing nursing students' abilities to recognize and respond to clinical deterioration. Nurse Educ Today. 2018 Mar;62:74-79. doi: 10.1016/j.nedt.2017.12.009


  18. Interprofessional Collaboration and Education

  19. Liaw SY, Zhou WT, Lau TC, Siau C, Chan SW. An interprofessional communication training using simulation to enhance safe care for a deteriorating patient. Nurse Educ Today. 2014 Feb;34(2):259-64. doi: 10.1016/j.nedt.2013.02.019

  20. Liaw SY, Siau C, Zhou WT, Lau TC. Interprofessional simulation-based education program: a promising approach for changing stereotypes and improving attitudes toward nurse-physician collaboration. Appl Nurs Res. 2014 Nov;27(4):258-60. doi: 10.1016/j.apnr.2014.03.005

  21. Liaw SY, Soh SL, Tan KK, Wu LT, Yap J, Chow YL, et al. Design and evaluation of a 3D virtual environment for collaborative learning in interprofessional team care delivery. Nurse Educ Today. 2019 Oct;81:64-71. doi: 10.1016/j.nedt.2019.06.012

  22. Liaw SY, Wu LT, Wong LF, Soh SL, Chow YL, Ringsted C, et al. "Getting everyone on the same page": interprofessional team training to develop shared mental models on interprofessional rounds. J Gen Intern Med. 2019 Dec;34(12):2912-2917. doi: 10.1007/s11606-019-05320-z

  23. Liaw SY, Tan JZ, Lim S, Zhou W, Yap J, Ratan R, Ooi SL, Wong SJ, Seah B, Chua WL. Artificial intelligence in virtual reality simulation for interprofessional communication training: Mixed method study. Nurse Educ Today. 2023;122:105718. doi:10.1016/j.nedt.2023.105718

  24. Liaw SY, Tan JZ, Bin Rusli KD, Ratan R, Zhou W, Lim S, Lau TC, Seah B, Chua WL. Artificial Intelligence Versus Human-Controlled Doctor in Virtual Reality Simulation for Sepsis Team Training: Randomized Controlled Study. J Med Internet Res. 2023 Jul 26;25:e47748. doi: 10.2196/47748. PMID: 37494112; PMCID: PMC10413090.

  25. Liaw SY, Wu LT, Soh SL, Ringsted C, Lau TC, Lim WS. Virtual reality simulation in interprofessional round training for health care students: a qualitative evaluation study. Clin Simul Nurs. 2020 Aug;45:42–26. doi: 10.1016/j.ecns.2020.03.013

  26. Liaw SY, Ooi SW, Rusli KD, Lau TC, Tam WW, Chua WL. Nurse-physician communication team training in virtual reality versus live simulations: randomized controlled trial on team communication and teamwork attitudes. J Med Internet Res. 2020 Apr 8;22(4):e17279. doi: 10.2196/17279

  27. Liaw SY, Ooi SL, Mildon R, Ang EN, Lau TC, Chua WL. Translation of an evidence-based virtual reality simulation-based interprofessional education into health education curriculums: an implementation science method. Nurse Educ Today. 2022 Mar;110:105262. doi: 10.1016/j.nedt.2021.105262

  28. Liaw SY, Tan KK, Wu LT, Tan SC, Choo H, Yap J, et al. Finding the right blend of technologically enhanced learning environments: randomized controlled study of the effect of instructional sequences on interprofessional learning. J Med Internet Res. 2019 May 28;21(5):e12537. doi: 10.2196/12537

  29. Liaw SY, Choo T, Wu LT, Lim WS, Choo H, Lim SM, et al. Wow, woo, win"- healthcare students' and facilitators' experiences of interprofessional simulation in three-dimensional virtual world: a qualitative evaluation study. Nurse Educ Today. 2021 Oct;105:105018. doi: 10.1016/j.nedt.2021.105018


  30. Manpower Nursing Competency Development

  31. Liaw SY, Koh Y, Dawood R, Kowitlawakul Y, Zhou W, Lau ST. Easing student transition to graduate nurse: a SIMulated Professional Learning Environment (SIMPLE) for final year student nurses. Nurse Educ Today. 2014 Mar;34(3):349-55. doi: 10.1016/j.nedt.2013.04.026

  32. Liaw SY, Palham S, Chan SW, Wong LF, Lim FP. Using simulation learning through academic-practice partnership to promote transition to clinical practice: a qualitative evaluation. J Adv Nurs. 2015 May;71(5):1044-54. doi: 10.1111/jan.12585.

  33. Tan KZY, Seah B, Wong LF, Lee CCS, Goh HS, Liaw SY. Simulation-Based Mastery Learning to Facilitate Transition to Nursing Practice [published online ahead of print, 2022 Jun 3]. Nurse Educ. 2022;10.1097/NNE.0000000000001224. doi:10.1097/NNE.0000000000001224

  34. Liaw SY, Rusli KD, McKenna L, Tan JZ, Lau ST. Effectiveness of an online program using telesimulation for academic–clinical collaboration in preparing nurse preceptors’ roles. [published online ahead of print, 2022 Apr 25]. J Clin Nurs. 2022;10.1111/jocn.16339. doi:10.1111/jocn.16339

  35. Rusli KD, Lau ST, Tan JZ, Liaw SY. Academic-practice collaboration using virtual telesimulaton to support students’ clinical practice. Nurse Educ. 2022 Aug 1. doi: 10.1097/NNE.0000000000001243


  36. Experiential learning using simulation

  37. Tan AJ, Lee CC, Lin PY, Cooper S, Lau ST, Chua WL, Liaw SY. Designing and evaluating the effectiveness of a serious game for safe administration of blood transfusion: a randomized controlled trial. Nurse Educ Today. 2017 Aug;55:38-44. doi: 10.1016/j.nedt.2017.04.027

  38. Chee EJ, Prabhakaran L, Neo LP, Carpio GA, Tan AJ, Lee CC, Liaw SY. Play and learn with patients-designing and evaluating a serious game to enhance nurses' inhaler teaching techniques: a randomized controlled trial. Games Health J. 2019 Jun;8(3):187-194. doi: 10.1089/g4h.2018.0073

  39. Liaw SY, Lau ST. Simulation as a substitute for clinical practice in the COVID-19 pandemic. TAPS. 2022 Jan;7(1):112-114. doi: 10.29060/TAPS.2022-7-1/PV2544

  40. Liaw SY, Carpio GA, Lau Y, Tan SC, Lim WS, Goh PS. Multiuser virtual worlds in healthcare education: a systematic review. Nurse Educ Today. 2018 Jun;65:136-149. doi: 10.1016/j.nedt.2018.01.006

  41. Mackey S, Tan KK, Ignacio J, Palham S, Dawood RB, Liaw SY. The learning experiences of senior student nurses who take on the role of standardised patient: a focus group study. Nurse Educ Pract. 2014 Nov;14(6):692-7. doi: 10.1016/j.nepr.2014.10.003

  42. Liaw SY, Scherpbier A, Rethans JJ, Klainin-Yobas P. Assessment for simulation learning outcomes: a comparison of knowledge and self-reported confidence with observed clinical performance. Nurse Educ Today. 2012 Aug;32(6):e35-9. doi: 10.1016/j.nedt.2011.10.006

  43. Liaw SY, Chen FG, Klainin P, Brammer J, O'Brien A, Samarasekera DD. Developing clinical competency in crisis event management: an integrated simulation problem-based learning activity. Adv Health Sci Educ Theory Pract. 2010 Aug;15(3):403-13. doi: 10.1007/s10459-009-9208-9

  44. Sim JJM, Rusli KDBC, Seah BC, Levett-Jones T, Lau Y, Liaw SY. Virtual Simulation to Enhance Clinical Reasoning in Nursing: A Systematic Review and Meta-analysis. Clin Simul Nurs. 2022;69:26-39. doi:10.1016/j.ecns.2022.05.006

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