With aging the prevalence of non-communicable diseases is increasing: Alzheimer’s disease, sarcopenia, diabetes, cancer, cardiovascular diseases. During the conference research experts and leaders in the field will discuss various biological aspects of aging and especially interventions as well as related mechanisms to sustain and/or restore functional capacity in older adults. The interventions to be discussed include nutritional supplements, caloric intake regulation, exercise, drugs, and others, in both human and animal models. The muscolo-skeletal, immune, metabolic and cognitive aspects of aging are among the topics to be covered. Scientists, clinicians and groups interested in restoring functional capacity and understanding the biology behind the effectiveness of these interventions are welcomed to attend this scientific conference.