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Affiliations
- Assistant Professor, Department of Physiology, National University of Singapore
- Healthy Longevity Translational Research Programme, NUS
- Joint Principal Investigator, IMCB, A*STAR
Research Areas of Interest:
- Neuronal network establishment and maintenance
- Neurodevelopmental disorders
- Neurodegeneration and neuronal aging
Selected Publications
- Yu N, Pasha M, Chua JJE. 2024. Redox changes and cellular senescence in Alzheimer’s disease. Redox Biol 70: 103048
- Altas B, Tuffy LP, Patrizi A, Dimova K, Soykan T, et al. 2023. Region-Specific Phosphorylation Determines Neuroligin-3 Localization to Excitatory Versus Inhibitory Synapses. Biol Psychiatry
- Qu Y, Lim JJ, An O, Yang H, Toh YC, Chua JJE. 2023. FEZ1 participates in human embryonic brain development by modulating neuronal progenitor subpopulation specification and migrations. iScience 26: 108497
- Trubetskoy V, Pardinas AF, Qi T, Panagiotaropoulou G, Awasthi S, et al. 2022. Mapping genomic loci implicates genes and synaptic biology in schizophrenia. Nature 604: 502-08
- Kok VJT, Tang JY, Eng GWL, Tan SY, Chin JTF, et al. 2022. SFPQ promotes RAS-mutant cancer cell growth by modulating 5′-UTR mediated translational control of CK1alpha. NAR Cancer 4: zcac027
- Chua JY, Ng SJ, Yagensky O, Wanker EE, Chua JJE. 2021. FEZ1 Forms Complexes with CRMP1 and DCC to Regulate Axon and Dendrite Development. eNeuro 8
- Yagensky O, Kohansal-Nodehi M, Gunaseelan S, Rabe T, Zafar S, et al. 2019. Increased expression of heme-binding protein 1 early in Alzheimer’s disease is linked to neurotoxicity. eLife 8: e47498
- Koopmans F, van Nierop P, Andres-Alonso M, Byrnes A, Cijsouw T, et al. 2019. SynGO: An Evidence-Based, Expert-Curated Knowledge Base for the Synapse. Neuron 103: 217-34 e4
- Butkevich E, Hartig W, Nikolov M, Erck C, Grosche J, et al. 2016. Phosphorylation of FEZ1 by Microtubule Affinity Regulating Kinases regulates its function in presynaptic protein trafficking. Scientific reports 6: 26965
- Binotti B, Pavlos NJ, Riedel D, Wenzel D, Vorbruggen G, et al. 2015. The GTPase Rab26 links synaptic vesicles to the autophagy pathway. eLife 4: e05597
Awards
- 2023 Yong Loo Lin School of Medicine Teaching Excellence Award (Individual)
- 2022 Yong Loo Lin School of Medicine Graduate Mentor of the Year (GRAMAY) Award
- 2022 Ng Shi Jun - Outstanding Undergraduate Researcher Prize
- 2019 Qu Yinghua - Outstanding Talk, SFN-SG meeting Society for Neuroscience, Singapore Chapter Meeting
- AY2019/2020 Yong Loo Lin School of Medicine Research Excellence Award
- 2019 Qu Yinghua - Best Short Talk – Neuroscience (11th Models of Physiology and Disease Symposium) NUS, Physiology Department
- 2019 Lee Jiaqi - Shaw Foundation Scholarship Duke-NUS
- 2006 Max Planck Research Fellowship Stipend
- 2000-2003 NUS Graduate Research Scholarship