The rise of
nanomedicine
A new area that combines nanodiagnostics and nanotherapy.Nanomedicine
(nanotechnology) is the medical application to improve our lives and health.
- Diagnosis, delivery, sensing/actuation purposes in a living organism.
- Detect and treat damage to the human body.
- To cure diseases and repair damaged tissues such as bone, muscle and nerve.
- Explore translational nanomedicines cancer, cardiovascular and neurological disorders, HIV/AIDS, and diabetes, as well as many types of inflammatory & infectious diseases.
ASPIRE
nanovaccine
It is derived from recombinant adenovirus-infected dendritic cells
- Peptide major histocompatibility complex class I (pMHC-I)
- Anti-PD1 Antibody
- B7 co-stimulatory molecules
![](https://medicine.nus.edu.sg/trp/nanomedicine/wp-content/uploads/sites/9/2022/08/aspire-slider.png)
ASPIRE
nanovaccine
It is derived from recombinant adenovirus-infected dendritic cells
- Peptide major histocompatibility complex class I (pMHC-I)
- Anti-PD1 Antibody
- B7 co-stimulatory molecules
![](https://medicine.nus.edu.sg/trp/nanomedicine/wp-content/uploads/sites/9/2022/08/aspire-slider.png)
mEVs ALLEVIATE ULCERATIVE COLITIS BY
regulating gut immunity & reshaping gut microbiota
![](https://medicine.nus.edu.sg/trp/nanomedicine/wp-content/uploads/sites/9/2022/08/aspire-slider-2.png)
mEVs ALLEVIATE ULCERATIVE COLITIS BY
regulating gut immunity & reshaping gut microbiota
![](https://medicine.nus.edu.sg/trp/nanomedicine/wp-content/uploads/sites/9/2022/08/aspire-slider-2.png)
MILD
microneedle pattern
It is a smart delivery platform serves as a promising carrier to improve COVID-19 vaccination efficacy through its dual capabilities of vaccine delivery and in situ data storage.
Thus exhibiting great potential to aid in containing COVID-19 pandemic or a resurge.
![](https://medicine.nus.edu.sg/trp/nanomedicine/wp-content/uploads/sites/9/2022/08/aspire-slider-3.png)
MILD
microneedle pattern
It is a smart delivery platform serves as a promising carrier to improve COVID-19 vaccination efficacy through its dual capabilities of vaccine delivery and in situ data storage.
Thus exhibiting great potential to aid in containing COVID-19 pandemic or a resurge.
![](https://medicine.nus.edu.sg/trp/nanomedicine/wp-content/uploads/sites/9/2022/08/aspire-slider-3.png)
get to know about our
Principal Investigators
![](https://medicine.nus.edu.sg/trp/nanomedicine/wp-content/uploads/sites/9/2022/08/Dr-Chen-Xiaoyuan-Shawn.png)
Dr Chen Xiaoyuan, Shawn
Director, Nanomedicine Translational Research Programme, NUS Yong Loo Lin School of Medicine
![](https://medicine.nus.edu.sg/trp/nanomedicine/wp-content/uploads/sites/9/2022/08/Dr-Lee-Chuen-Neng-.png)
Dr Lee Chuen Neng
Deputy Director, Nanomedicine Translational Research Programme, NUS Yong Loo Lin School of Medicine
![](https://medicine.nus.edu.sg/trp/nanomedicine/wp-content/uploads/sites/9/2022/08/Dr-Dan-Yock-Young.png)
Dr Dan Yock Young
Principal Investigator, Nanomedicine Translational Research Programme, NUS Yong Loo Lin School of Medicine
![](https://medicine.nus.edu.sg/trp/nanomedicine/wp-content/uploads/sites/9/2022/09/jiongwei.jpg)
Dr Wang Jiongwei
Principal Investigator, Nanomedicine Translational Research Programme, NUS Yong Loo Lin School of Medicine
![](https://medicine.nus.edu.sg/trp/nanomedicine/wp-content/uploads/sites/9/2022/09/qianqian.jpg)
Dr Ni Qianqian
Principal Investigator, Nanomedicine Translational Research Programme, NUS Yong Loo Lin School of Medicine
![](https://medicine.nus.edu.sg/trp/nanomedicine/wp-content/uploads/sites/9/2022/09/jingjing.jpg)
Dr Zhang Jingjing
Principal Investigator, Nanomedicine Translational Research Programme, NUS Yong Loo Lin School of Medicine
![](https://medicine.nus.edu.sg/trp/nanomedicine/wp-content/uploads/sites/9/2022/09/tangwei.jpg)
Dr Tang Wei
Principal Investigator, Nanomedicine Translational Research Programme, NUS Yong Loo Lin School of Medicine
![](https://medicine.nus.edu.sg/trp/nanomedicine/wp-content/uploads/sites/9/2022/09/stormgert.jpg)
Dr Storm Gert
Principal Investigator, Nanomedicine Translational Research Programme, NUS Yong Loo Lin School of Medicine
![](https://medicine.nus.edu.sg/trp/nanomedicine/wp-content/uploads/sites/9/2022/09/Lingwen-Ding-Nw-2.png)
Dr Lingwen Ding
Principal Investigator, Nanomedicine Translational Research Programme, NUS Yong Loo Lin School of Medicine
![](https://medicine.nus.edu.sg/trp/nanomedicine/wp-content/uploads/sites/9/2022/08/Dr-Chen-Xiaoyuan-Shawn.png)
Dr Chen Xiaoyuan, Shawn
Director, Nanomedicine Translational Research Programme, NUS Yong Loo Lin School of Medicine
![](https://medicine.nus.edu.sg/trp/nanomedicine/wp-content/uploads/sites/9/2022/09/ChesterLeeDrum.jpg)
Dr Chester Lee Drum
Deputy Director, Nanomedicine Translational Research Programme, NUS Yong Loo Lin School of Medicine
![](https://medicine.nus.edu.sg/trp/nanomedicine/wp-content/uploads/sites/9/2022/08/Dr-Dan-Yock-Young.png)
Dr Dan Yock Young
Principal Investigator, Nanomedicine Translational Research Programme, NUS Yong Loo Lin School of Medicine
3
project themes
supported by shared technologies & cores
Nanoplatforms for multimodality molecular imaging
Nanovaccines
Gene and drug delivery
![](https://medicine.nus.edu.sg/trp/nanomedicine/wp-content/uploads/sites/9/2024/04/NM-1.jpg)
A DNA origami device spatially controls CD95 signalling to induce immune tolerance in rheumatoid arthritis
On April 9th, our recently work about the DNA origami device which can spatially control
![](https://medicine.nus.edu.sg/trp/nanomedicine/wp-content/uploads/sites/9/2023/06/Top2.png)
Theranostics got the latest Journal Impact Factor (IF) of 12.4!
Theranostics has just received its latest Impact Factor for the year 2022, which is 12.4.
![](https://medicine.nus.edu.sg/trp/nanomedicine/wp-content/uploads/sites/9/2023/07/Pic-3.png)
Gas-Mediated Tumor Energy Remodeling for Sensitizing Mild Photothermal Therapy
Abstract The metabolic reprogramming of tumors requires high levels of adenosine triphosphate (ATP) to maintain
![](https://medicine.nus.edu.sg/trp/nanomedicine/wp-content/uploads/sites/9/2023/07/Pic-2.png)
Tumor-microenvironment-responsive poly-prodrug encapsulated semiconducting polymer nanosystem for phototherapy-boosted chemotherapy
Abstract Phototherapy-induced hypoxia in the tumor microenvironment (TME) is responsible for diminished therapeutic efficacy. Designing
![](https://medicine.nus.edu.sg/trp/nanomedicine/wp-content/uploads/sites/9/2022/10/ange202112925-fig-0001-m.jpg)
Coordinating the mechanism of actions of ferroptosis and photothermal effect for cancer theranostics
Abstract The objective of this study was to determine the safety, kinetics, and dosimetry of
![](https://medicine.nus.edu.sg/trp/nanomedicine/wp-content/uploads/sites/9/2022/12/Pic-2-e1686807937331.webp)
Targeting the activity of T cells by membrane surface regulation for cancer theranostics
T cells play a determining role in the immunomodulation and prognostic evaluation of cancer