Hanry Yu

Hanry Yu

PhD in Cell Biology, Duke University

Professor


+65-6516 3466 &
+65-6516 1644 (Office);
+65-6516 4885 (Lab)

+65-6778 8161


physyuh@nus.edu.sg


Translational Mechanobiology Lab

Affiliations

  • Professor, Department of Physiology, National University of Singapore
  • Institute of Digital Medicine (WisDM) Translational Research Programme, NUS Medicine

Research Areas of Interest:

  • Drug Testing Platforms
  • Digital Liver Projects
  • Micro-tissue Fabrication Factory

Selected Publications

  1. Gupta, K., Ng, I.C., Balachander, G.M., Nguyen, B.P., Tucker-Kellogg, L., Low, B.C., and Yu, H. (2020) Bile canaliculi contract autonomously by releasing calcium into hepatocytes via mechanosensitive calcium channel. Biomaterials, November 2020; 259: 120283.
  2. Tasnim, F., Singh, N.H., Tan, E.K.F., Xing, J., Li, H., Hissette, S., Manesh, S., Fulwood, J., Gupta, K., Ng, C.W., Xu, S., Hill, J., and Yu, H. (2020) Tethered primary hepatocyte spheroids on polystyrene multi-well plates for high-throughput drug safety testing. Scientific Reports, 16 Mar 2020; 10: 4768.
  3. Tasnim, F., Xing, J., Huang, X., Mo, S., Wei, X., Tan, M.-H. and Yu, H. (2019) Generation of Mature Kupffer Cells from Human Induced Pluripotent Stem Cells. Biomaterials, February 2019; 192: 337-391.
  4. Yu, Y., Wang, J., Ng, C.W., Ma, Y., Mo, S., Fong, L.S.E., Xing, J., Song, Z., Xie, Y., Si, K., Wee, A., Welsch, R.E., So, P.T.C., and Yu, H. (2018) Deep learning enhances automated scoring of liver fibrosis stages. Scientific Reports, 30 October 2018; 8: 16016.
  5. Li, Q., Zhang, Y., Pluchon, P., Robens, J., Herr, K., Mercade, M., Thiery, J.P., Yu, H.*, and Viasnoff, V. (2016) Extracellular matrix scaffolding guides lumen elongation by inducing anisotropic intercellular mechanical tension. Nature Cell Biology, April 2016; 8: 311-318.

Awards

  • 1987-1990 Division of Biomedical Sciences pre-doctoral fellowship, Washington University School of Medicine
  • 1995-1997 Human Frontier Science Program long-term fellowship
  • 1995 Alexander von Humboldt research scholarship
  • 2002 Young Researcher Award, National University of Singapore
  • 2009 Faculty Research Excellence Award AY2007/2008, National University Health System
  • 2013 A*STAR Scientist-Entrepreneur Award 2013, Team Leader for team HistoIndex Pte Ltd
  • 2016 Scientist-Entrepreneur Award Prof Hanry Yu, InvitroCue Pte Ltd
  • 2017 IPOS Award for IP Champions, WIPO-IPOS IP Awards 2017, for Invitrocue Pte Ltd
  • 2021 Yong Loo Lin School of Medicine Researcher of the Year Award – AY2019/2020
  • 2022 Long Service Medal for 2022 National Day Awards
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