Olona Ferrer Antoni Maria

Olona Ferrer Antoni Maria

 PhD

Lecturer

t.olona1@nus.edu.sg

ORCiD

Affiliations

  • Lecturer, Academy for Healthy Longevity and Department of Physiology, National University of Singapore

Research Interests

  • Postgraduate learning design and implementation
  • Geroscience and Geromedicine
  • Immunometabolism in ageing

Selected Publications:

  1. Peter Rossi-Smith , Joohee Kim , Kamil Skirlo , Trevor Ferris , Jack P Green , Cari Stek , Kristin K Huse , Paige M Mortimer , Antoni Olona , Cecilia Wieder , Raymond Moseki , Mariana Silva Dos Santos , James I MacRae , Shiranee Sriskandan , Timothy M D Ebbels , Robert J Wilkinson, Alice E Denton, Nicholas J Matheson, Paras K Anand, Graeme Meintjes, David C Thomas, Rachel P J Lai. “Taurine transport is a critical modulator of ionic fluxes during NLRP3 inflammasome activation” Cell Reports 2025 Oct 28;44(10):116317.
  2. Charlotte Hateley , Antoni Olona , Laura Halliday , Matthew L Edin , Jeong-Hun Ko , Roberta Forlano , Ximena Terra , Fred B Lih , Raúl Beltrán-Debón , Penelopi Manousou , Sanjay Purkayastha , Krishna Moorthy , Mark R Thursz , Guodong Zhang, Robert D Goldin , Darryl C Zeldin , Enrico Petretto , Jacques Behmoaras. “Multi-tissue profiling of oxylipins reveal a conserved up-regulation of epoxide:diol ratio that associates with white adipose tissue inflammation and liver steatosis in obesity” EBioMedicine Vol. 103, May 2024.
  3. Antoni Olona, Stuart Leishman, Paras K. Anand. “The NLRP3 inflammasome: regulation by metabolic signals” Trends in Immunology, Vol. 43, No. 12, Dec 2022.
  4. Struan Bourke,   Laura Urbano, Megan M. Midson, Antoni Olona, Basma Qazi-Choudhry,   Maryna Panamarova,   Ferran Valderrama,   Nicholas J. Long, Lea-Ann Dailey and Mark Green. “Nearly monodispersed, emission-tuneable conjugated polymer nanoparticles” Sensors and diagnostics; 1185–1188, Sep. 2022.
  5. Claire Hamilton*, Antoni Olona*, Stuart Leishman , Kelly MacDonald-Ramsahai , Shamshad Cockcroft , Gerald Larrouy-Maumus , Paras K Anand. “NLRP3 Inflammasome Priming and Activation Are Regulated by a Phosphatidylinositol-Dependent Mechanism” Immunohorizons;6 (8): 659 Aug. 2022. (*Co-first Authors)
  6. Sneha Muralidharan ,Federico Torta, Michelle K Lin , Antoni Olona , Marta Bagnati , Aida Moreno-Moral , Jeong-Hun Ko , Shanshan Ji, Bo Burla , Markus R Wenk, Hosana G Rodrigues , Enrico Petretto, Jacques Behmoaras. “Immunolipidomics Reveals a Globoside Network During the Resolution of Pro-Inflammatory Response in Human Macrophages”. Frontiers in immunology; Volume 13- article 926220. June 2022.
  7. Antoni Olona , Charlotte Hateley, Ana Guerrero, Jeong-Hun Ko, Michael R Johnson, Paras K Anand, David Thomas, Jesus Gil, Jacques Behmoaras. “Cardiac glycosides cause cytotoxicity in human macrophages and ameliorate white adipose tissue homeostasis”, British Journal of Pharmacology; 1874–1886 May 2022.
  8. Antoni Olona , Subhankar Mukhopadhyay , Charlotte Hateley , Fernando O Martinez , Siamon Gordon, Jacques Behmoaras “Adipoclast: a multinucleated fat-eating macrophage”, BMC Biology; 19;19(1):246., Oct. 2021.
  9. Antoni Olona , Charlotte Hateley, Sneha Muralidharan , Markus R Wenk , Federico Torta , Jacques Behmoaras. “Sphingolipid metabolism during Toll-like receptor4 (TLR4)-mediated macrophage activation”, British Journal of Pharmacology; 178:4575–4587. August 2021.
  10. Jeong-Hun Ko , Antoni Olona , Adonia E Papathanassiu, Norzawani Buang, Kwon-Sik Park, Ana S H Costa, Claudio Mauro, Christian Frezza, Jacques Behmoaras. “BCAT1 affects mitochondrial metabolism independently of leucine transamination in activated human macrophages”, Journal of Cell Science; 133(22): jcs247957. Nov. 2020.
  11. Ana Guerrero , Nicolás Herranz, Bin Sun, Verena Wagner, Suchira Gallage, Romain Guiho, Katharina Wolter, Joaquim Pombo, Elaine E Irvine, Andrew J Innes, Jodie Birch, Justyna Glegola, Saba Manshaei , Danijela Heide , Gopuraja Dharmalingam, Jule Harbig, Antoni Olona, Jacques Behmoaras, Daniel Dauch, Anthony G Uren, Lars Zender, Santiago Vernia, Juan Pedro Martínez-Barbera, Mathias Heikenwalder, Dominic J Withers, Jesús Gil. “Cardiac glycosides are broad-spectrum senolytics”. Nature Metabolism; 1(11): 1074–1088. Oct.r 2019.
  12. Marie Pereira, Tai-Di Chen, Norzawani Buang, Antoni Olona, Jeong-Hun Ko, Maria Prendecki, Ana SH Costa, Efterpi Nikitopoulou, Laura Tronci, Charles D Pusey, H Terence Cook, Stephen P McAdoo, Christian Frezza, Jacques Behmoaras. “Acute Iron Deprivation Reprograms Human Macrophage Metabolism and Reduces Inflammation In Vivo”. Cell Reports; 28(2): 498–511.e5. July 2019.
  13. Antoni Olona, Ximena Terra, Jeong-Hun Ko, Carme Grau-Bové, Montserrat Pinent, Anna Ardevol , Ana Garcia Diaz, Aida Moreno-Moral, Matthew Edin, David Bishop-Bailey, Darryl C Zeldin, Timothy J Aitman, Enrico Petretto, Mayte Blay, Jacques Behmoaras. “Epoxygenase inactivation exacerbates diet and aging-associated metabolic dysfunction resulting from impaired adipogenesis”. Molecular Metabolism; 11: 18–32. May 2018.

Awards

  • 2024 Duke-NUS Teaching Scholar Initiative
  • 2023 Khoo Postdoctoral Fellowship
  • 2016 Imperial College Scholarship
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