Huang Hua

 

Huang Hua

PhD

Research Assistant Professor

phshhua@nus.edu.sg

Director, Electrophysiology Core Facility, Yong Loo Lin School of Medicine, NUS

Publications

  • Maity A, Perotto S, Moschetta M, Huang H, Sardar S, Paternò GM, Tian J, Klein M, Adamo G, Lanzani G, Soci C. Resonant Enhancement of Polymer-Cell Optostimulation by a Plasmonic Metasurface. ACS Omega. 2022 Nov 16;7(47):42674-42680.
  • Hu Z, Zhang B, Lim LJY, Loh WZK, Yu D, Tan BWQ, Liang MC, Huang Z, Leo CH, Huang H, Soong TW. S-Nitrosylation-Mediated Reduction of CaV1.2 Surface Expression and Open Probability Underlies Attenuated Vasoconstriction Induced by Nitric Oxide. Hypertension. 2022 Dec;79(12):2854-2866.
  • Zhai J, Navakkode S, Yeow SQZ, Krishna-K K, Liang MC, Koh JH, Wong RX, Yu WP, Sajikumar S, Huang H, Soong TW. Loss of CaV1.3 RNA editing enhances mouse hippocampal plasticity, learning, and memory. Proc Natl Acad Sci USA. 2022 Aug 9;119(32):e2203883119. 
  • Huang, H., Tan, B.Z., Shen, Y., Tao, J., Jiang, F., Sung, Y.Y., Ng, C.K., Raida, M., Kohr, G., Higuchi, M. et al. (2012) RNA editing of the IQ domain in Ca(v)1.3 channels modulates their Ca(2)(+)-dependent inactivation. Neuron. 73, 304-316.(impact factor: 13.974)
  • Huang H., Wang J., Soong T.W. (2013) Splicing and Editing to Customize CaV Channel Structures for Optimal Neural Function. In: Stephens G., Mochida S. (eds) Modulation of Presynaptic Calcium Channels. Springer, Dordrecht. ISBN 978-94-007-6333-3 (book chapter contribution)
  • Huang, H., Yu, D. and Soong, T.W. (2013) C-terminal alternative splicing of CaV1.3 channels distinctively modulates their dihydropyridine sensitivity. Mol Pharmacol. 84, 643-653. (impact factor: 4.128)
  • Huang, H., Ng, C.Y., Yu, D., Zhai, J., Lam, Y. and Soong, T.W. (2014) Modest CaV1.342-selective inhibition by compound 8 is beta-subunit dependent. Nat Commun. 5, 448. (impact factor: 11.329)
  • Li, G., Wang, J., Liao, P., Bartels, P., Zhang, H., Yu, D., Liang, M.C., Poh, K.K., Yu, C.Y., Jiang, F., Yong, T.F., Wong, Y.P., Hu, Z., Huang, H., Zhang, G., Galupo, M.J., Bian, J.S., Ponniah, S., Trasti, S.L., See, K., Foo, R., Hoppe, U.C., Herzig, S., and Soong, T.W. (2017) Exclusion of alternative exon 33 of CaV1.2 calcium channels in heart is proarrhythmogenic. Proc Natl Acad Sci USA. 114, E4288-E4295 (impact factor: 9.661)
  • Bartels, P., Yu, D., Huang, H., Hu, Z., Herzig, S., Soong, T.W. (2018) Alternative splicing at N-terminus and domain I modulates Cav1.2 inactivation and surface expression. Biophys J. 2018 May 8;114(9):2095-2106. doi: 10.1016/j.bpj.2018.03.029. (impact factor: 3.632)
  • Huang, H*., Kapeli, K., Jin, W., Wong, Y.P., Arumugam, T.V., Koh, J.H., Srimasorn, S., Mallilankaraman, K., Chua, J.J.E, Yeo G.W., Soong, T.W.* (2018) Tissue-selective restriction of RNA editing of CaV1.3 by splicing factor SRSF9. Nucleic Acids Res. 2018 May 4. doi: 10.1093/nar/gky348. (impact factor: 10.162, *co-corresponding author)
  • Mei Q, Bansal A, Jayakumar MKG, Zhang Z, Zhang J, Huang H, Yu D,Ramachandra CJA, Hausenloy DJ, Soong TW, Zhang Y. Manipulating energy migration within single lanthanide activator for Switchable up conversion emissions towards bidirectional photoactivation. Nat Commun. 2019 Sep 27;10(1):4416. (impact factor: 11.329)
  • Huang, H*., Tay, S. H., Ng, W., Ng, S. Y. & Soong, T. W. Targeting novel human transient receptor potential ankyrin 1 splice variation with splice-switching antisense oligonucleotides. Pain. 162, 2097-2109 (2021). (impact factor: 6.029, *corresponding author)
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