Research Areas of Interest:

• Exercise and age-associated immunosenescence
• Exercise and immune modulation in cancer patients
• Exercise and inflammation in cardiovascular disease and cancer
• High intensity interval training (HIIT) and health benefits in cardiovascular disease and cancer
• Novel biomarkers of healthy ageing

Selected Publications

• Soh J, Lim ZX, Lim EH, Kennedy BK, Goh J. Ironing out exercise on immuno-oncological outcomes. J Immunother Cancer. 2022;10(9):e002976. doi:10.1136/jitc-2021-002976
• Matysek A, Studnicka A, Smith WM, Hutny M, Gajewski P, Filipiak KJ, Goh J, Yang G. Influence of Co-morbidities During SARS-CoV-2 Infection in an Indian Population. Front Med (Lausanne). 2022 Aug 1;9:962101. doi: 10.3389/fmed.2022.962101
• Lim ZX, Goh J. Effects of blood flow restriction (BFR) with resistance exercise on musculoskeletal health in older adults: a narrative review. Eur Rev Aging Phys Act. 2022;19(1):15. Published 2022 Jun 20. doi:10.1186/s11556-022-00294-0
• Oudbier SJ, Goh J, Looijaard SMLM, Reijnierse EM, Meskers CGM, Maier AB. Pathophysiological mechanisms explaining the association between low skeletal muscle mass and cognitive function [published online ahead of print, 2022 Jun 6]. J Gerontol A Biol Sci Med Sci. 2022;glac121. doi:10.1093/gerona/glac121
• Harper C, Gopalan V, Goh J†. Exercise rescues mitochondrial coupling in aged skeletal muscle: a comparison of different modalities in preventing sarcopenia. J Transl Med 2021;16;19(1):71. doi: 10.1186/s12967-021-02737-1.
• Gopalan V, Yaligar J, Michael N, Kaur K, Anantharaj R, Verma SK, Sadananthan SA, Le GTT, Goh J, Velan SS. A 12-week aerobic exercise improves metabolic function with lower adipose tissue and ectopic fat in high fat diet fed rats. Biosci Rep. 2021 Jan 12: BSR20201707. doi:1 0.1042/BSR20201707.
• Merchant RA, Goh J, Chan YH, Lim JY, Vellas B. Slow Gait, Subjective Cognitive Decline and Motoric Cognitive Syndrome: Prevalence and Associated Factors in Community Dwelling Older Adults. J Nutr Health Aging 2021 25(1):48-56. doi: 10.1007/s12603-020-1525-y.
• Goh J†, Hofmann P, Aw NH, Tan PL, Tschakert G, Mueller A, Wong SC, Tan F, Gan LS. Concurrent high-intensity aerobic and resistance exercise modulates systemic release of alarmins (HMGB1, S100A8/A9, HSP70) and inflammatory biomarkers in healthy young men: a pilot study. Transl Med Commun 2020; 5:4. doi: 10.1186/s41231-020-00056-z
• Lee SY, Fam KD, Chia KL, Yap MMC, Goh J, Yap EPH, Chotirmall SH, Lim CL. Age-related bone loss is associated with FGF21 but not IGFBP1 in healthy adults. Exp Physiol 2020; doi: 10.1113/EP088351
• Aw NH, Canetti E, Suzuki K, Goh J†. Monocyte subsets in atherosclerosis and modification with exercise in humans. Antioxidants 2018; 7(12): doi: 10.3390/antiox7120196
• Goh J†, Behringer M. Exercise Alarms the Immune System: An HMGB1 Perspective. Cytokine 2018; 110: 222-225.
• Yang Y, Wang RY, Bay PB, Huang J, Teo HWJ, Goh J. Effects of Consecutive versus Nonconsecutive Days of Resistance Training on Strength, Body Composition and Red Blood Cells. Front Physiol 2018; 9:725. doi: 10.3389/fphys.2018.00725. eCollection 2018.
• Ge X, Ciol MA, Pettan-Brewer C, Goh J, Rabinovitch P, Ladiges W. Self-motivated and stress-response performance assays in mice are age-dependent. Exp Gerontol 2017; 91: 1-4. doi: 10.1016/j.exger.2017.02.001.
• Goh J†, Goh KP, Abbasi A. Exercise and adipose tissue macrophages: new frontiers in obesity research? Front Endocrinol 2016;7: 65.
• Goh J, Ladiges W. Voluntary Wheel Running in Mice. Curr Protoc Mouse Biol 2015; DOI: 10.1002/9780470942390.mo140295
• Goh J†, Niksirat N, Campbell K. Exercise Training and Immune Crosstalk in the Tumor Microenvironment: An Immunological Approach for Exercise Intervention in Breast Cancer Prevention and Treatment. Am J Transl Res 2014; 6: 422-438.
• Goh J, Endicott E, Ladiges W. Pre-tumor exercise decreases breast cancer in old mice in a distance-dependent manner. Am J Cancer Res 2014; 4: 378-384.
• Goh J, Ladiges WC. Exercise enhances wound healing and prevents cancer progression during aging by targeting macrophage polarity. Mech Ageing Devt 2014; 139: 41-48.
• Goh J, Tsai J, Bammler TK, Farin FM, Endicott E, Ladiges WC. Exercise Training in Transgenic Mice is Associated with Attenuation of Early Breast Cancer Growth in a Dose-Dependent Manner. PLOS ONE 2013; 8(11): e80123
• Siegel MP, Kruse SE, Percival JM, Goh J, White CC, Hopkins HC, Kavanagh TJ, Szeto HH, Rabinovitch PS, Marcinek DJ. Mitochondrial targeted peptide rapidly improves mitochondrial energetics and skeletal muscle performance in aged mice. Aging Cell 2013; 12(5):763-771.
• Goh J, Ladiges W. A Novel Long-Term, Short Interval Physical Activity Regime Improves Body Composition in Mice. BMC Res Notes 2013; 6: 66.
• Goh J, Kirk E, Lee SX, Ladiges WC. Exercise, Physical Activity and Breast Cancer: The Role of Tumor-Associated Macrophages. Exerc Immunol Rev 2012; 18: 157-175.
• Goh J, Enns L, Fatemi S, Hopkins H, Morton J, Pettan-Brewer C, Ladiges W. Mitochondrial targeted catalase suppresses invasive breast cancer in mice. BMC Cancer 2011; 11: 191. doi:10.1186/1471-2407-11-191.