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Oncoproteins play essential roles in the development of various human cancers. This study led by A/P Gautam Sethi et al confirms a novel oncoprotein that increases tumour growth in mouse
This review, led by Dr Raghav Sundar and Dr Soon Yu Yang, show that covid-19 vaccines provide significantly lower protection in immunocompromised patients. It highlights the importance of a second
Chemotherapy-associated adverse events can result in early termination of cancer treatment. In this article, A/Prof Franco-Obregon demonstrates the sensitivity of breast cancer cells to combinational therapy of chemotherapy and pulsed
Metastasis is the main cause of mortality in breast cancer patients. CD82, a metastasis suppressor has been shown to be lowly expressed in metastatic breast cancer. This review by Prof
Summary Several multi-cancer early detection (MCED) tests based on novel blood-based biomarkers, such as cell-free DNA (cfDNA) or circulatory miRNA, help to make cancer screening cost-effective and more accessible by
Summary The combination of chemotherapy (or targeted therapy) with immunotherapy is emerging rapidly as a promising strategy in the first line treatment against several tumor types. This study led by
Glioblastoma (GBM) is the most aggressive form of solid brain tumours with limited treatment options. Nanoparticles have been shown to induce an antitumour effect and target GBM selectively. Researchers in
This study reports a novel inhibitor oxide (MPO) which promotes inhibition of growth in pancreatic and hepatocellular cancer cell lines by inducing cell cycle arrest. Hence authors in this study
Hepatitis B virus (HBV) infection is one of the main causes of Hepatocellular carcinoma (HCC) which is one of leading causes of cancer related deaths globally. Pseudogenes have recently been
Fatty acids oxidation (FAO) confers Epithelial-to-mesenchymal transition causing enhanced tumorigenicity and drug resistance to cancer cells. This study by N2CR member A/Prof Tam Wai Leong and his team demonstrates that