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Hepatocellular carcinoma (HCC) remains difficult to treat due to a lack of effective treatment options. While various drugs have shown promising preclinical results, poor drug combination design results in less
Primary Epstein-Barr virus (EBV)-positive nodal T/NK-cell lymphoma (PTCL-EBV) is an aggressive and poorly understood disease that occurs mostly in East Asia. In this collaborative study, led by A/Prof Ng Siok
Adult T-cell leukemia/lymphoma (ATL) is a genetically complex form of blood cancer. In this study led by A/Prof Takaomi Sanda, the authors investigated the roles, functions as well as factors
The leakage of chemotherapeutic drugs into tissues other than the tumour can result in adverse side effects. Efforts have been made to devise novel drug delivery methods to improve drug
Platinum resistance is a major contributor to ovarian cancer mortality and presents a considerable clinical challenge, necessitating the development of better treatments for platinum-resistant patients. In this editorial, A/Prof. David
Aberrant activation of the transcription factor, STAT3, can promote cancer progression and occurs in various cancer types including breast, prostate, pancreas, liver, brain and leukemia. This study, co-led by A/Prof
Black cardamom (A. subulatum), a commonly used spice, is also used in traditional medicine as a component of ayurvedic formulations for the treatment of lung conditions. In this article co-authored
The drug Selinexor blocks specific protein that has been shown to be overexpressed in many types of cancer. Authors in this study evaluated the tolerability and the safety of this
Any disruption in RNA processing by RNA binding proteins (RBPs) may lead to cancers. This research article published by Natures Communications and helmed by Associate Professor Polly Chen provides insights
Incidence rate for breast cancer has been increasing in females globally. Immunotherapy has recently emerged as a promising anti-cancer strategy for prolonged survival in breast cancer patients. Recently, gold nanoparticles