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Summary Several multi-cancer early detection (MCED) tests based on novel blood-based biomarkers, such as cell-free DNA (cfDNA) or circulatory miRNA, help to make cancer screening cost-effective and more accessible by
Summary The combination of chemotherapy (or targeted therapy) with immunotherapy is emerging rapidly as a promising strategy in the first line treatment against several tumor types. This study led by
Glioblastoma (GBM) is the most aggressive form of solid brain tumours with limited treatment options. Nanoparticles have been shown to induce an antitumour effect and target GBM selectively. Researchers in
This study reports a novel inhibitor oxide (MPO) which promotes inhibition of growth in pancreatic and hepatocellular cancer cell lines by inducing cell cycle arrest. Hence authors in this study
Hepatitis B virus (HBV) infection is one of the main causes of Hepatocellular carcinoma (HCC) which is one of leading causes of cancer related deaths globally. Pseudogenes have recently been
Fatty acids oxidation (FAO) confers Epithelial-to-mesenchymal transition causing enhanced tumorigenicity and drug resistance to cancer cells. This study by N2CR member A/Prof Tam Wai Leong and his team demonstrates that
More than 50% of colorectal cancer patients develop metastases to the liver. Liver resection is considered the only treatment for patients with colorectal liver metastases. This review by A/Prof Glenn
Epstein-Barr virus (EBV) is associated with nasopharyngeal carcinoma (NPC) and provides a potential target for dendritic cell vaccine therapy. This phase 1 clinical study led by Prof Goh Boon Cher
Women diagnosed with the biologically aggressive triple-negative (TNBC) and endocrine-refractory subtypes of breast cancer confront a bleak prognosis because they respond poorly to conventional chemotherapy. Researchers from the NUS Yong