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Phase I trials are an essential part of bringing new cancer therapies into the clinic. As participation in Phase I trials usually requires life expectancy of greater than 3 months
Cancer is known to kill mainly by spread to distant organs and destroying normal function. For a long time, the relationship between the original cancer, and the metastases in distant
Mitochondria are specialised compartments of the cell that function as powerhouses by playing a crucial role in metabolism. The transfer of mitochondria between cells is a biological phenomenon implicated in
Early-stage colorectal cancer (CRC) patients are recommended to get a review every 3-6 months for 5 years after operation for the detection of cancer recurrence. As an increasing number of
Non-Hodgkin’s lymphoma is a common form of blood cancer with a high proportion of patients either developing treatment resistance or relapsing after initial treatment. The combination of multiple therapies is
Hepatocellular carcinoma (HCC) remains difficult to treat due to a lack of effective treatment options. While various drugs have shown promising preclinical results, poor drug combination design results in less
Primary Epstein-Barr virus (EBV)-positive nodal T/NK-cell lymphoma (PTCL-EBV) is an aggressive and poorly understood disease that occurs mostly in East Asia. In this collaborative study, led by A/Prof Ng Siok
Adult T-cell leukemia/lymphoma (ATL) is a genetically complex form of blood cancer. In this study led by A/Prof Takaomi Sanda, the authors investigated the roles, functions as well as factors
The leakage of chemotherapeutic drugs into tissues other than the tumour can result in adverse side effects. Efforts have been made to devise novel drug delivery methods to improve drug
Platinum resistance is a major contributor to ovarian cancer mortality and presents a considerable clinical challenge, necessitating the development of better treatments for platinum-resistant patients. In this editorial, A/Prof. David