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Dr Shruti BHATT

Haematological

The central focus of research is to identify treatment strategies and underlying mechanisms of therapy-resistant myeloid tumors by studying clonal evolutionary path and cell death mechanisms, particularly the mitochondrial pathway of apoptosis.

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Prof Dario CAMPANA

Haematological
Research focus is on the development of innovative technologies to treat cancer with immune cells, and their translation into first-in human clinical trials.
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Dr CHEONG Jit Kong

Haematological

Research focus is on uncovering and characterising novel signalling nodes of oncogenic RAS-driven human cancers to facilitate the development of tractable therapeutic modalities.

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Prof CHNG Wee Joo

Haematological
Research focus is on blood cancers to understand how the disease develops and find better ways to treat them.
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Dr Anand Devaprasath JEYASEKHARAN

Haematological
Clinical research focuses on combinatorial drug therapy trials in lymphoma, and methods for evaluating cancer phenotypes for personalized treatment choice. Biological research focuses on understanding the signalling pathways involved in activation of immune responses after chemotherapy.
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Prof KOH Liang Piu

Haematological
Research focuses mainly on clinical Haematopoietic Stem Cell Transplantation in particular Nonmyeloablative Stem Cell Transplant, haploidentical donor transplant, Umbilical Cord Blood Transplantation in Haematological Malignancies. He also the leading primary investigators on clinical trials on Infectious Complications in Haematological / Haematopoietic Stem Cell Transplantation Recipients, studies on Graft vs. Host Disease prevention and treatment.
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A/Prof NG Siok Bian

Haematological
Research focus is to identify and validate novel markers of prognostic and therapeutic importance in EBV-associated T- and NK-cell lymphomas and lymphoproliferative diseases, a group of aggressive tumours which are prevalent in Asia.
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Dr OOI Gaik Ming, Melissa

Haematological
She is currently the leukaemia group lead in National University Cancer Institute of Singapore and is also heavily involved in myeloma, leukaemia and myelodysplasia clinical care and research. She is also interested in health service research and geriatric research.
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Dr TAY Kah Ping, Andy

Haematological

The research focus of the Tay lab is tissue-specific drug delivery and immunotherapeutics against cancer.

 
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Prof YEOH Eng Juh, Allen

Haematological
Research focus is on improving Acute Lymphoblastic Leukaemia treatment in children and adults by better prediction of each patient’s risk of relapse using highly sensitive biomarkers like RNA-Seq and MRD measurements. A/Prof Yeoh works on immune cell therapy especially CAR-T cell therapy for leukaemia with Prof Dario Campana in NUSMed.
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Dr ZHOU Jianbiao

Haematological

Research focus is on the drug resistance mechanisms and aggressive phenotypes in hematologic malignancies, as well as the development predictive markers, novel therapeutic targets.

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A/Prof YEOH Eng Juh, Allen

Haematological
Research focus is on improving Acute Lymphoblastic Leukaemia treatment in children and adults by better prediction of each patient’s risk of relapse using highly sensitive biomarkers like RNA-Seq and MRD measurements. A/Prof Yeoh works on immune cell therapy especially CAR-T cell therapy for leukaemia with Prof Dario Campana in NUSMed.
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A/Prof CHEE Cheng Ean

Colorectal
Research interest is in precision oncology in colorectal, pancreas and liver cancers. I develop and conduct clinical trials with novel therapeutics and work with collaborators within and outside Singapore on translational and biomarker research in these areas. In addition, I am interested in healthcare delivery and personalizing care for our cancer survivors.
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Dr CHEONG Jit Kong

Gastric

Research focus is on uncovering and characterising novel signalling nodes of oncogenic RAS-driven human cancers to facilitate the development of tractable therapeutic modalities.

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Dr CHIA Le Bin, Gloryn

Colorectal

The research focuses on developing novel immunotherapies that harness the immune system to target tumors, with a particular emphasis on neoantigens. These neoantigens, which arise from tumor-specific mutations, represent a distinct class of antigens recognized by T cells, making them promising targets for precision cancer therapies. By identifying and characterizing these neoantigens, the aim is to develop personalized cancer vaccines and T cell-based therapies that improve the immune system’s capacity to recognize and eliminate tumors.

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Dr ENG Wee Ling, Gracie

Gastric/ Nasopharyngeal/ Colorectal

Research interest focuses on the role of miRNAs as a biomarker for diagnosis and prognosis, and as a potential therapeutic biomolecule in a variety of diseases.

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Dr LOW Jun Siong

Gastric/ Nasopharyngeal/ Colorectal
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Prof Shazib PERVAIZ

Colorectal
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Prof SO Bok Yan, Jimmy

Gastric
Research focus is to improve outcomes of patients with gastric or esophageal cancer through early detection, better understanding of their origins and novel treatment.
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Dr Sriram SRIDHARAN

Gastric / Colorectal

Research focus is to study how DNA replication is a source of genome instability. I aim to understand why and how the (epi)genome acts as an impediment to faithful DNA replication. 

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Dr Supriya SRIVASTAVA

Gastric

Pathologist with a specific focus on solid cancers, particularly gastrointestinal cancers. Research focuses on the identification and validation of biomarkers that aid in the early diagnosis of gastric cancers as well as metaplastic lesions of stomach, that are considered preneoplastic and could be targeted at an early stage thereby improving the patient outcome.

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A/Prof TAN Ker Kan

Colorectal
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Dr TAY Kai Xun, Joshua

Nasopharyngeal

Dr Joshua Tay leads a cancer genomics laboratory, with special expertise in micro-dissected gene expression profiling from archival FFPE tissue specimens. His lab has built and patented gene expression signatures to predict patient outcomes for precision medicine.

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A/Prof YAP Suen Mei, Celestial

Gastric
The expertise and commitment of my research extend expansively across human diseases and human biology including cancer. In addition, we have special interests in the roles of the cytoskeleton in cancer. My research group has developed both in vitro techniques incorporating molecular and bioinformatics technology, as well as in vivo approaches to investigating human diseases such as cancers.
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Dr YONG Wei Peng

Gastric
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Dr TAY Kai Xun, Joshua

Nasopharyngeal

Dr Joshua Tay leads a cancer genomics laboratory, with special expertise in micro-dissected gene expression profiling from archival FFPE tissue specimens. His lab has built and patented gene expression signatures to predict patient outcomes for precision medicine.

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A/Prof YAP Suen Mei, Celestial

Gastric
The expertise and commitment of my research extend expansively across human diseases and human biology including cancer. In addition, we have special interests in the roles of the cytoskeleton in cancer. My research group has developed both in vitro techniques incorporating molecular and bioinformatics technology, as well as in vivo approaches to investigating human diseases such as cancers.
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Dr CHEONG Jit Kong

Breast

Research focus is on uncovering and characterising novel signalling nodes of oncogenic RAS-driven human cancers to facilitate the development of tractable therapeutic modalities.

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A/Prof DENG Lih Wen

Gynaecological
Research focus is on understanding the cellular and molecular mechanism in cancer development and therapy resistance for the development of diagnostic markers and selective therapeutics against cancer resistance and metastasis.
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Dr CHIA Le Bin, Gloryn

Gynaecological

The research focuses on developing novel immunotherapies that harness the immune system to target tumors, with a particular emphasis on neoantigens. These neoantigens, which arise from tumor-specific mutations, represent a distinct class of antigens recognized by T cells, making them promising targets for precision cancer therapies. By identifying and characterizing these neoantigens, the aim is to develop personalized cancer vaccines and T cell-based therapies that improve the immune system’s capacity to recognize and eliminate tumors.

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Dr KONG Li Ren

Breast

Research focus is in targeted intervention based on germline mutations.

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Dr Alan Prem KUMAR

Breast
Research focus is on uncovering new cues that drive the spread of cancer and develop target-based precision therapies to prevent metastasis in several types of female reproductive cancers.
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Prof LEE Soo Chin

Breast
Research focuses on novel therapeutics and predictive biomarkers in breast cancer. Her team has identified a biomarker detectable in blood that predicts breast cancer recurrence, and that can be used to select patients for a novel targeted therapy.
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A/Prof LIM Gkeok Stzuan, Diana

Gynaecological
Dr Diana Lim is a senior consultant pathologist and director of the Diagnostic Molecular Oncology Centre (DMOC) in National University Hospital. Her subspecialty and research interest lies in gynaecologic and molecular pathology.
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Dr LIM Si Jing, Joline

Breast
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Dr NGOI Yan Li, Natalie

Gynaecological
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Prof Shazib PERVAIZ

Breast
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Dr TAI Yee Kit Alex

Breast

Research focus is on exploring the therapeutic benefits of pulsed electromagnetic fields (PEMF) as an exercise-mimetic to enhance the vulnerability of tumor cells to chemotherapy.

 

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A/Prof TAN Shao Peng, David

Gynaecological
Research is focused on the development of biomarkers and novel therapeutic agents in gynaecological cancers; in understanding the mechanisms of treatment response and resistance in these cancers, with the aim of developing biomarkers to help stratify patients into optimal treatment strategies.
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Dr TAY Kah Ping, Andy

Breast/ Gynaecological

The research focus of the Tay lab is tissue-specific drug delivery and immunotherapeutics against cancer.

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Prof Ashok VENKITARAMAN

Breast
Research focus is on deciphering the mechanisms underlying cancer susceptibility to intercept cancer evolution.
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A/Prof YAP Suen Mei, Celestial

Breast
The expertise and commitment of my research extend expansively across human diseases and human biology including cancer. In addition, we have special interests in the roles of the cytoskeleton in cancer. My research group has developed both in vitro techniques incorporating molecular and bioinformatics technology, as well as in vivo approaches to investigating human diseases such as cancers.
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A/Prof YIP Wai Cheong, George

Breast
Research interest is in understanding the biological roles of molecules called glycosaminoglycans and proteoglycans and to determine if these biomolecules can be used to predict patient outcomes and the development of new treatment.
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Prof Ashok VENKITARAMAN

Breast
Research focus is on deciphering the mechanisms underlying cancer susceptibility to intercept cancer evolution.
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A / Prof YAP Suen Mei, Celestial

Breast
The expertise and commitment of my research extend expansively across human diseases and human biology including cancer. In addition, we have special interests in the roles of the cytoskeleton in cancer. My research group has developed both in vitro techniques incorporating molecular and bioinformatics technology, as well as in vivo approaches to investigating human diseases such as cancers.
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Dr CHEONG Jit Kong

Liver/ Pancreatic

Research focus is on uncovering and characterising novel signalling nodes of oncogenic RAS-driven human cancers to facilitate the development of tractable therapeutic modalities.

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A/Prof Glenn Kunnath BONNEY

Liver/ Pancreatic
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A/Prof CHEN Leilei, Polly

Liver
Research focus is on identifying how the harmful changes that occur in RNA molecules trigger a cell to develop into cancer which can eventually lead to the unsatisfactory treatment outcomes for patients with cancers. The long-term goal of Dr Chen’s team is to develop novel cancer therapies targeting these cancer-associated RNA changes.
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A/Prof CHEW Suk Peng, Valerie

Liver

Research delves into deciphering the intricate immune landscape and crosstalk within the tumor microenvironment of hepatocellular carcinoma (HCC), with a keen focus on uncovering biomarkers and therapeutic avenues.

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Prof Shazib PERVAIZ

Pancreatic
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Dr TAY Kah Ping, Andy

Liver/ Pancreatic

The research focus of the Tay lab is tissue-specific drug delivery and immunotherapeutics against cancer.

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Prof Ashok VENKITARAMAN

Pancreatic
Research focus is on deciphering the mechanisms underlying cancer susceptibility to intercept cancer evolution.
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A/Prof CHEW Suk Peng, Valerie

Liver

Research delves into deciphering the intricate immune landscape and crosstalk within the tumor microenvironment of hepatocellular carcinoma (HCC), with a keen focus on uncovering biomarkers and therapeutic avenues.

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Prof Shazib PERVAIZ

Pancreatic
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Dr CHEONG Jit Kong

Lung

Research focus is on uncovering and characterising novel signalling nodes of oncogenic RAS-driven human cancers to facilitate the development of tractable therapeutic modalities.

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Prof GOH Boon Cher

Head and Neck/ Lung
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Prof Shazib PERVAIZ

Lung
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A/Prof Gautam SETHI

Lung
Research focus is to elucidate the mechanism(s) of activation of oncogenic transcription factors and identification of novel inhibitors of these proteins for cancer prevention as well as therapy.
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A/Prof TAM Kit Chung, John

Thoracic
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Dr TAY Kai Xun, Joshua

Head and Neck

Dr Joshua Tay leads a cancer genomics laboratory, with special expertise in micro-dissected gene expression profiling from archival FFPE tissue specimens. His lab has built and patented gene expression signatures to predict patient outcomes for precision medicine.

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Prof Daniel TENEN

Lung
Research focus is on gene regulation in normal cells and cancer, mainly in leukaemia, lung cancer, and liver cancer. Current interests are transcription factors, epigenetics, and weird long noncoding RNAs in these processes, as well as targeting the oncofoetal protein SALL4.
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Dr WONG Lea Choung

Head and Neck
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Prof Yang ZHANG

Lung/ Thoracic / Head and Neck/ Thyroid

Built on cutting-edge artificial intelligence (AI) and deep-learning techniques, we are developing new methods for protein and RNA structure prediction and protein designs. We are particularly interested in the application of the AI-based computational methods for effective cancer therapeutics, with focuses on anti-cancer peptide-drug conjugates (PDCs) and T-cell receptor (TCR)-based adoptive therapy..

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