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Research News

TAL1 hijacks MYCN enhancer that induces MYCN expression and dependence on mevalonate pathway in T-cell acute lymphoblastic leukemia

11 October 2023

This study, co-led by A/Prof Takaomi Sanda and A/Prof Allen Yeoh, delves into T-cell acute lymphoblastic leukemia (T-ALL...

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PI3K/AKT/mTOR signalling transduction pathway and targeted therapies in cancer

11 October 2023

The PI3K/AKT/mTOR (PAM) signaling pathway is crucial in regulating cell survival, growth, and the cell cycle. Its comple...

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N2CR Invited Speaker Series with Dr Sophia Adamia

12 September 2023

N2CR had the honour of having Dr Sophia Adamia, from the Beth Israel Deaconess Medical Center in Boston, visit us on 5 S...

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NUS-Kanagawa Symposium 2023

9 September 2023

On 4th and 5th September 2023, N2CR had the honour of holding the NUS-Kanagawa Symposium 2023,  jointly with CSI Singap...

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Research News

Understanding Autophagy in Pancreatic Cancer: From Bioinformatics to Clinical Insights

15 August 2023

Pancreatic cancer is a devastating illness with a poor five-year survival rate. A team of researchers, which includes A/...

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Possible reasons behind the resistance of certain cancer cells to the chemotherapy drug 5-FU

15 August 2023

5-Fluorouracil (5-FU) is a common chemotherapy drug widely used around the world to treat cancer but development of resi...

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Research News

Berberine: Fighting Breast Cancer’s Spread through Gut Bacteria & Natural Chemicals

12 July 2023

A team of researchers, led by A/Prof Gautam Sethi from N2CR, conducted a study investigating the therapeutic possibiliti...

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Research News

Targeting Wnt signalling in osteosarcoma

5 July 2023

Osteosarcoma, the most common bone cancer, usually affects children or adolescents during their pubertal growth spurt. P...

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Research News

EBV-associated Smooth Muscle Tumours: Novel Findings

5 July 2023

Epstein-Barr virus (EBV)-associated smooth muscle tumours (EBV-SMTs) are rare tumours that can arise in immunosuppressed...

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