A breakthrough study, co-led by N2CR member A/Prof Raghav Sundar and includes Prof Jimmy So, A/Prof Yvonne Tay and Dr Yong Wei Peng, has provided new hope for gastric cancer patients with peritoneal metastasis, a highly lethal form of cancer. Gastric cancer, the fifth most common cancer worldwide, frequently spreads to the peritoneum, resulting in poor survival rates. The study, published in Gastroenterology (and accompanied by a clinical trial published in ESMO Open), used advanced genomic and molecular techniques to understand how gastric cancer spreads to the peritoneum. Key findings include identifying genetic changes and the tumor microenvironment as critical factors, paving the way for targeted therapies and earlier detection.
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