Research News

Improved drug combination design for hepatocellular carcinoma

Hepatocellular carcinoma (HCC) remains difficult to treat due to a lack of effective treatment options. While various drugs have shown promising preclinical results, poor drug combination design results in less successful treatment of HCC. This collaborative work with Dr Cheng Ean Chee, A/Prof Glenn Bonney and team, lead by A/Prof Edward Chow, has found that drug combination design can be improved through the use of their drug combination prediction platform to identify combination therapies that are of high therapeutic potential for HCC.

Read more: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9377092/

Share this story:
Facebook
Twitter
LinkedIn

Related Research News

Research News

Next-Generation Sequencing in Metastatic Breast Cancer: A Game Changer for Asian Patients

This study, led by N2CR members Dr Joline Lim and A/Prof David Tan, looks at the use of next-generation sequencing …

Read More →
Research News

Mechanisms of sensitivity and resistance to CDK4/CDK6 inhibitors in hormone receptor-positive breast cancer treatment

Cell cycle dysregulation, a key feature of cancer, leads to excessive cell division. CDK4 and CDK6 are essential for cell …

Read More →
Research News

Macrophage Signatures that Help Predict Lymphoma Patient’s Survival Rate

Macrophages are “big eaters” in our body; they are immune cells that engulf and kill invading organisms and cancer cells. …

Read More →