The leakage of chemotherapeutic drugs into tissues other than the tumour can result in adverse side effects. Efforts have been made to devise novel drug delivery methods to improve drug efficacy and reduce the occurrence of adverse side effects. This study by Dr Alan Prem Kumar and colleagues describes their development of an anticancer drug delivery system targeted to the protein, CD44, which is highly expressed on cancer cells. Preclinical testing of their novel chemotherapeutic drug delivery method was shown to be safe and effective in reducing tumour growth, highlighting their formulation as a promising methodology for future development.

Read more: https://pubmed.ncbi.nlm.nih.gov/35875198/