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Selected Publications

  1. Loh, A., Angelina, C., Wong, M. K., Tan, S. H., Sukhatme, S. A., Yeo, T., Lim, S. B., Lee, Y. T., Soh, S. Y., Leung, W., Chang, K., Chua, Y. W., Alkaff, S., Lim, T., Lim, C. T., & Chen, Z. X. (2022). Pro-metastatic and mesenchymal gene expression signatures characterize circulating tumor cells of neuroblastoma patients with bone marrow metastases and relapse. Frontiers in oncology, 12, 939460.
  2. Kuick, C. H., Tan, J. Y., Jasmine, D., Sumanty, T., Ng, A., Venkatesh, B., Chen, H., Loh, E., Jain, S., Seow, W. Y., Ng, E., Lian, D., Soh, S. Y., Chang, K., Chen, Z. X., & Loh, A. (2022). Mutations of 1p genes do not consistently abrogate tumor suppressor functions in 1p-intact neuroblastoma. BMC cancer, 22(1), 717.
  3. Wong, R. L. Y., Wong, M. R. E., Kuick, C. H., Saffari, S. E., . . . Chen, Z. X., Iyer, P., Tan, E. E. K., Soh, S. Y., Iyer, N. G., Fan, Q., and Loh, A. H. P. (2021). Integrated Genomic Profiling and Drug Screening of Patient-Derived Cultures Identifies Individualized Copy Number-Dependent Susceptibilities Involving PI3K Pathway and 17q Genes in Neuroblastoma.Front Oncol, 11, 709525.
  4. Hee, E., Wong, M. K., Tan, S. H., Choo, Z., . . . Chen, Z., Chang, K. T. E., and Loh, A. H. P. (2020). Neuroblastoma patient-derived cultures are enriched for a mesenchymal gene signature and reflect individual drug response. Cancer Sci, 111(10), 3780-3792. doi: 10.1111/cas.14610 (IF=6.716)
  5. Choo, Z., Loh, A. H. P., and Chen, Z. X. (2019). Destined to Die: Apoptosis and Pediatric Cancers. Cancers, 11(11), 1623. doi: 10.3390/cancers11111623 (IF=6.639)
  6. Angelina, C., Tan, I. S. Y., Choo, Z., Lee, O. Z. J., Pervaiz, S., and Chen, Z. X. (2017). KIF1Bbeta increases ROS to mediate apoptosis and reinforces its protein expression through O 2(-) in a positive feedback mechanism in neuroblastoma. Sci Rep, 7(1), 16867. doi:10.1038/s41598-017-17192-6 (IF=4.379)
  7. Cai, W., Xiong Chen, Z.#, Rane, G., Satendra Singh, S., Choo, Z., Wang, C., . . . Prem Kumar, A. (2017). Wanted DEAD/H or Alive: Helicases Winding Up in Cancers. J Natl Cancer Inst, 109(6). doi:10.1093/jnci/djw278 #co-first authors (IF=13.506)
  8. Li, S., Fell, S. M., Surova, O., Smedler, E., Wallis, K., Chen, Z. X., . . . Schlisio, S. (2016). The 1p36 Tumor Suppressor KIF 1Bbeta Is Required for Calcineurin Activation, Controlling Mitochondrial Fission and Apoptosis. Dev Cell, 36(2), 164-178. doi:10.1016/j.devcel.2015.12.029 (IF=12.270)
  9. Chen, Z. X., Wallis, K., Fell, S. M., Sobrado, V. R., Hemmer, M. C., Ramskold, D., . . . Schlisio, S. (2014). RNA helicase A is a downstream mediator of KIF1Bbeta tumor-suppressor function in neuroblastoma. Cancer Discov, 4(4), 434-451. doi:10.1158/2159-8290.CD-13-0362 (IF=39.397)