Careers

Job Description

The National University of Singapore invites applications for position of Research Assistant in the Ion Channel and Transporter Lab, Department of Physiology, Yong Loo Lin School of Medicine. The candidate will be involved in the investigation of calcium channel alternative splicing and RNA editing using transgenic mouse model and patch-clamp electrophysiological methods for brain slice recordings. Appointments will be made on a one-year contract basis in the first instance, with the possibility of extension for a second year.

The Research Assistant (RA) will be responsible to, and work closely with, the Principal Investigator, the Director of the NUS Electrophysiology Core, and study team members to ensure the successful completion of work assigned. The RA’s principal role will be to work in patch-clamp electrophysiology (training will be provided), molecular and cell biology and working with rodents as models of health and disease.

Main Duties and Responsibilities
The Research Assistant will work closely with the PI or the Director of the NUS Electrophysiology Core. The duties include, but are not exclusive to the following:

1. Perform patch-clamp electrophysiological recordings on excitable cells such as neurons and muscle cells or on brain slices;
2. Conduct experiments employing molecular and cell biological and biochemical methods;
3. Conduct imaging studies;
4. Contribute to lab duties and other work-related activities;
5. Keep records and work done and to present for discussions;
6. Assist with any other duties of a similar nature that are delegated by the PI or Director of NUS Electrophysiology Core

Qualifications

The applicant should:

1. Have a first degree with good results or holds a Bachelor’s degree in Biomedical Science or related disciplines;
2. Be able to work independently and in a team;
3. Have knowledge or skills in basic animal handling or behavioural studies;
4. Have experiences in Molecular and Cell Biology and Biochemistry;
5. Have experience or willingness to be trained in patch-clamp electrophysiological techniques and brain slice recordings.

Apply via this website: https://careers.nus.edu.sg/job-invite/24243/ 

We regret that only shortlisted candidates will be notified.

A Research Fellow position is available to investigate the role of epigenetic modifiers in rhabdomyosarcoma. Self-motivated candidates with a recent Ph.D. degree and research experience in molecular biology or cancer biology are encouraged to apply. Prior experience in epigenetics and animal models is preferred.

Interested candidates should send their CV and names of three referees to:

Prof Reshma Taneja, Department of Physiology, National University of Singapore, Singapore. [Email:phsrt@nus.edu.sg].

For more information, please visit our website:

https://medicine.nus.edu.sg/phys/lab/Tanejas_Lab/index.html

A Research Assistant position is available to investigate the role of epigenetic modifiers in rhabdomyosarcoma. Competency in molecular biology and animal work is preferred. The candidate should have good communication skills and the ability to work individually as well as on team projects.

Interested candidates should send their CV and names of three referees to:

Prof Reshma Taneja, Department of Physiology, National University of Singapore, Singapore. Email: phsrt@nus.edu.sg
For more information, please visit our website:
https://medicine.nus.edu.sg/phys/lab/Tanejas_Lab/index.html

The Role

To support the administration and coordination of the 1) upcoming Integrative Health Minor (IHM) slated to launch in AY23/24, 2) Asia-Pacific Biomedical Science Educators Association (APBSEA) founded by NUSMed, and 3) Intercalated Year Programmes (IYPs) and Pathways.

The roles will include:

• Working across medical science departments, College of Design and Engineering (CDE), School of Computing (SOC) and industry partners to support the running and coordination of the IHM modules in particular the Capstone Module in terms of publicity, enrolment, setup and monitoring of teaching-learning activities and learning management system, assessment matters, and feedback and evaluation.
• Working with APBSEA country leads to support the running and coordination of faculty development activities, website maintenance, and all other matters pertaining to APBSEA that may extend the influence of NUSMed.
• Working with partner faculties and universities, MOH, MOE and NUS Senior Management to establish IYPs and monitor outcome through stakeholder-sensing and coordination, proposal-writing and student-tracking.
• Working across NUHS, NUS faculties/schools and external stakeholders to support the running, coordination and outcome-monitoring of Pathways and in relation to UROP.

Job Description

Provide support for Integrative Health Minor (to be launched in AY23/24). Key activities include:

• Publicize the programme when approved
• Handle enrolment of students across NUS
• Coordinate across modules in collaboration with medical science departments, NUHS, CDE, SOC and industry partners
• Handle processes and workflows pertaining to Integrative Health Capstone module

Provide support for NUS-led APBSEA. Key activities include:

• Update and maintenance of website with relevant resources and content
• Coordinate with country leads to organize in-person or virtual faculty development activities
• Monitor general email, update member registry and welcome new members
• Facilitate APBSEA partnership with conferences
• Schedule meetings, write meeting notes and craft appointment and other official letters

Provide support for IYPs, Pathways and UROP. Key activities include:

• Coordinate meetings with partner institutions and schools/faculties, and write notes
• Draft UCEP proposals and coordinate with ministries and senior management
• Organize roadshows and selection processes, and bridge to partner institutions and schools/faculties
• Track, monitor and support students’ transition, progress and exit
• Plan, schedule and organize Pathways especially I&T, working across multiple stakeholders
• Support RO colleagues to curate, match and track projects in terms of funding and outcome, and nudging students towards UROP uptake

Qualifications

• Degree in any field with some background/expertise in communication and education will be advantageous
• Able to communicate well especially in writing
• Strong command of English especially in proposal-writing
• Proficient with MS Office (Word, Excel, PowerPoint, Forms, Teams). Knowledge of website, graphic and media design is a plus
• Knowledge in education design and social media-savviness is a plus
• Meticulous in handling documents and communications
• Sense of urgency with good time management
• Willing and able to reflect and self-learn at reasonable pace
• Dependable, reliable and collegial personality
• Sense of excellence and able to integrate things learned
• Good people-sensing and culturally-sensitive
• Self-driven when independent and collegial when in team
• Strong interpersonal and organizational skills

For more information, visit here.

A postdoctoral fellow position is available immediately at the A*STAR IMCB – Laboratory of Chromatin Dynamics & Disease Epigenetics.

Our lab has a long-standing interest in understanding the epigenetic mechanisms of lineage plasticity in early development (Hu et al., Nat Cell Biol. 2020 Feb;22(2):175-186). More recently, we have broadened our investigations to study how cancer cells undergo epigenetic reprogramming to induce phenotypic plasticity. Indeed, chromatin-associated proteins are emerging as new drug targets for a variety of diseases, especially cancer. We are interested to study how chromatin deficiencies underlie human diseases, with a strong focus on therapeutics development. We employ varied experimental approaches such as Next-Generation Sequencing, genome-editing, genetic/chemical screens as well as cancer models (PDXs, tumor organoids etc) to address our questions of interest. The postdoc candidate will conduct research to identify novel chromatin targets for downstream therapeutics development, and will work closely with our clinical collaborators at major hospitals and drug development colleagues at A*STAR EDDC.

We are looking for a highly motivated postdoc with relevant training in cancer research, biochemistry or related fields. Candidates with prior experience in epigenetic technologies, chromatin biology, drug development, genetic screens and/or animal experimentation will be considered favourably.

Specific requirements:

(1) Possess a Ph.D in relevant field.

(2) Good publication record in peer-reviewed journals.

(3) Expertise in routine cell biology, biochemistry and molecular biology techniques

(4) Highly motivated and passionate for research.

(5) Able to undertake independent research and be an effective team player.

An attractive remuneration package that is commensurate with the qualifications, track record and working experience of the successful candidate will be provided. The successful candidate will also have the opportunity to lead projects and work collaboratively with others in conceptualizing and conducting research projects. Interested applicants should email his/her curriculum vitae, a cover letter addressing research interest, experience and skills, and contact information of three referees to Dr. Wee-Wei Tee (wwtee@imcb.a-star.edu.sg).

For more information about the lab, please see: https://wwteelab.com

The National University of Singapore invites applications for Research Fellow in the Department of Physiology, Yong Loo Lin School of Medicine.

Laboratory of Dr John Chua

The research aims to investigate mechanisms of neuronal aging using reprogrammed neurons.

Purpose of the post

The Post-Doctoral Fellow (PDF) will be responsible to, and work closely with the Principal Investigator (PI), other members of the laboratory as well as scientific collaborators to ensure the successful completion of the project. We seek an enthusiastic and self-motivated research fellow to join our team.

Main duties and responsibilities

The Post-Doctoral Fellow will be responsible for the following:
· Be proactive in driving the project, working closely with the PI and other members of the laboratory as well as clinical and scientific collaborators to ensure the generation and collection of appropriate data
· Be updated on the latest literature on the research focus and how our research can help fill the gaps in knowledge or provide solutions
· Be responsible for analyzing, integrating and presenting data collected from the various research efforts and to develop new tools for analyses as required
· Train/Teach juniors in the laboratory as well as attachment students
· Presentation of data to lab members and collaborators during regular meetings
· Write reports
· Write manuscripts for publication consideration on research
· Write and/or assist in writing grants for continued support of research
· Have opportunity to present research in meetings (local/overseas)
· Assist in any other duties delegated by the PI

Qualifications

The applicant should have a PhD in Life Sciences or related disciplines with a background in neurobiology and expertise in ageing biology preferable.
· Expertise in working with cell culture; experience with human embryonic stem cells (hESCs), and or iPSCs and their differentiation in neuronal cell lineages is highly desirable
· Experience in high-resolution time-lapse in vivo cellular and molecular imaging
· Competency in molecular biology, biochemical and microscopic techniques
· Excellent writing and presentation skills
· Ability to work independently and on team projects

Formal application: Please submit your application, indicating current/expected salary, supported by a detailed CV (including personal particulars, academic and employment history, complete list of publications/oral presentations and full contacts of 3 referees to Dr John Chua email: phsjcje@nus.edu.sg.
We regret that only shortlisted candidates will be notified.

A research fellow position is available to investigate the molecular mechanisms that instigate the functional decline of neural stem cells during aging. We are seeking self-motivated, creative and talented individuals with expertise and experience in the areas of neuroscience (particularly neural stem cell biology) and epigenetics. Candidates with experience in aging biology, telomere biology and mouse models will be considered favorably. Please send your CV and a cover letter (including scientific interest, short- and long-term goals) to phsostd@nus.edu.sg. For more information, please visit (https://medicine.nus.edu.sg/phys/research/research-programs/cancer-programme/ong-sek-tong-derrick/).

We are seeking highly motivated individuals who wish to pursue research in the field of Aging and Cancer Stem Cell Biology. Positions are available at the undergraduate and graduate levels. Interested applicants should email enquiries and/or relevant documents to Derrick at phsostd@nus.edu.sg.

Graduate student (Ph.D.) positions:

(on-going recruitment)

Applicants should hold a basic science degree in Biology. During the Ph.D. candidature, students should expect to acquire knowledge and skills in various areas, including stem cell and differentiation assays, molecular cloning, lentiviral-mediated gene (or shRNA) delivery, realtime qRT-PCR, western blotting, indirect immunofluorescence microscopy, transcriptomic analysis and intracranial injection experiments. In our laboratory, we employ these techniques to investigate the molecular bases of deregulated brain stem cell activity during aging and cancer (https://medicine.nus.edu.sg/phys/research/research-programs/cancer-programme/ong-sek-tong-derrick/). Students will be nurtured to become critical and rigorous scientists who can design experiments and interpret data independently. Interested candidates should send their CV, with a brief summary of research experience (if any), to phsostd@nus.edu.sg. We welcome applicants from all over the world. Students in our laboratory may be funded under a variety of scholarships, including the NUS Research and SINGA scholarships. Please refer to the following website for various scholarship options (http://www.nus.edu.sg/admissions/graduate-studies/scholarships-financial-aid-and-fees/scholarships-awards.html).