Our People
Precision Medicine TRP
Secondary (Basic Sciences) Members
Dean Ho
Professor
Area of Research
- Digital medicine
- Personalized medicine technologies
Research Interests
- Application of artificial intelligence for personalized human treatment for oncology, infectious disease and other human diseases
- Nanomedicine
Polly Chen Leilei
Associate Professor
Area of Research
- Transcriptomic instability of human cancers
Research Interests
- Hepatocellular carcinoma
- Epigenetic mechanisms of tumourigenesis
- RNA editing and alternative splicing
Deng Lih Wen
Associate Professor
Area of Research
- Cellular and molecular mechanism in cancer development
- Developing novel targets for therapeutic cancer intervention
Research Interests
- Genomic instability and chromatin dynamics in cancer development
- Mechanisms of therapy resistance
- Therapeutic potential of targeting cancer metabolism and tumor microenvironment
- Cancer oxidative stress and glutathione homeostasis
Dennis Kappei
Assistant Professor
Area of Research
- Non-coding DNA elements
- Telomere biology
Research Interests
- Telomere-binding proteins
- Cellular senescence
Tan Tin Wee
Associate Professor
Area of Research
- Bioinformatics
- Advanced Internet Network Protocols and Applications in Biological Sciences
Research Interests
- Biodatabases; Large-scale workflow integration; grid computing; immunomics & vaccine informatics.
- Computer protocols, applications and standards for biological entities, nomenclature, pathways, diagramming and software tools interfacing.
- Advanced Internet research network engineering for bioinformatics applications.
- Internet protocols for bioinformatics and multilingual internet names.
Yvonne Tay Mei Sian
Assistant Professor
Area of Research
- Characterization of non-coding RNA regulatory networks in cancer
Research Interests
- Mechanisms of microRNA function
- Non-coding RNA in cancer biology and their potential therapeutic applications
Ling Shuo-Chien
Associate Professor
Area of Research
- Aging
- Neurodegeneration
Research Interests
- Pathogenic mutations in neurodegeneration
- Neuronal biology
- Contribution of neuronal cell types to disease progression
Low Chian-Ming
Associate Professor
Area of Research
- Neurobiology
- Brain imaging
Research Interests
- Pain and NMDA receptors
- Neuroprotective rational drug design
- Neuroinflammation and neurodegeneration
Gavin Dawe
Associate Professor
Area of Research
- Neurosciences
- Neurodegeneration
- Neuropsychiatry
- Peptide pharmacology
Research Interests
- Neurobiology of amyloid precursor protein (APP)
- Neuropeptides and stapled peptides
- Neuropsychopharmacology of antipsychotics, anxiolytics, and antidepressants
Hanry Yu
Professor
Area of Research
- Disease models on chip
- AI diagnostics
- Biology of liver disease and regeneration
Research Interests
- Drug Testing Platforms
- Digital Liver Projects
- Micro-tissue Fabrication Factory
Volker Patzel
Area of Research
- RNA technologies
- Nuclei acid delivery
Research Interests
- miRNA::target interaction
- Design of trans-splicing RNA
- Design of genes and vectors for preclinical and clinical investigation
- Delivery of nucleic acids into target cells including stem cells
- Novel approaches for genetic intervention
- Identification and characterization of non-coding RNA
Precision Medicine TRP
Secondary (Clinical) Members
Dan Yock Young
Associate Professor
Area of Research
- Cardiovascular Diseases: Cellular & Molecular Mechanisms
- Metabolic Diseases & Diabetes: Therapy
Research Interests
- Liver Stem Cells
- Liver Cancer
- Fatty Liver
Ngiam Kee Yuan
Associate Professor
Area of Research
- Thyroid & Endocrine Surgery
Research Interests
- Endocrine and Metabolic Surgery
- AI Applications in Healthcare.
Lee Yung Seng
Professor
Area of Research
- Childhood obesity and co-morbidities
- Developmental origins of health and disease
Research Interests
- Obesity and insulin resistance
- Pathogenesis of obesity related morbidities