Research Theme
Early Cancer Intervention (ECI) focuses on understanding how cell autonomous and non-cell autonomous changes contribute to cancer initiation and relapse post-treatment with the goal of developing innovative approaches to delay, prevent or treat cancer at its earliest stages.
Theme Leads
Prof Ashok VENKITARAMAN
Theme Lead
Research focus is on deciphering the mechanisms underlying cancer susceptibility to intercept cancer evolution.
A/Prof Polly CHEN
Theme Lead
Research focus is on identifying how the harmful changes that occur in RNA molecules trigger a cell to develop into cancer which can eventually lead to the unsatisfactory treatment outcomes for patients with cancers. The long-term goal of Dr Chen’s team is to develop novel cancer therapies targeting these cancer-associated RNA changes.
Theme Members - Secondary
Dr LI Jingmei
Research focuses on multi-ancestry genome-wide association studies (GWAS), polygenic risk scores (PRS), DNA methylation as environmental proxies, the biological significance of germline variants, integrating genetics into national health programs, and understanding factors that defy high-risk predictions in breast cancer.
Prof Vinay TERGAONKAR
My lab aims to understand fundamental mechanisms by which novel RNAs regulate carcinogenesis.
