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PGRN-EGFR Crosstalk Modulates ADAR1-Mediated Liver Immunity

30 July 2024

In this study, led by A/Prof Polly Chen, multi-omics approaches revealed that MDA5 loss in ADAR1-deficient livers does n...

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Research News

Next-Generation Sequencing in Metastatic Breast Cancer: A Game Changer for Asian Patients

11 July 2024

This study, led by N2CR members Dr Joline Lim and A/Prof David Tan, looks at the use of next-generation sequencing (NGS)...

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Mechanisms of sensitivity and resistance to CDK4/CDK6 inhibitors in hormone receptor-positive breast cancer treatment

1 July 2024

Cell cycle dysregulation, a key feature of cancer, leads to excessive cell division. CDK4 and CDK6 are essential for cel...

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Research News

Macrophage Signatures that Help Predict Lymphoma Patient’s Survival Rate

14 June 2024

Macrophages are “big eaters” in our body; they are immune cells that engulf and kill invading organisms and ...

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Get to know a professor with over 30 years of experience!

10 June 2024

Here’s part 3 of the N2CR Cancer Researchers’ Stories! Let’s get to know Professor Shazib Pervaiz, who...

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Research News

PHF2 regulates genome topology and DNA replication in neural stem cells via cohesion

4 June 2024

When a cell divides to make new cells, it needs to copy its DNA so that each new cell has the same genetic information. ...

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Dr Derrick Ong shares more about his work on glioblastomas!

4 June 2024

N2CR’s Cancer Researchers’ Stories is back! 👨‍🔬 👩‍🔬 Introducing Dr Derrick Ong from the Depa...

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A Fun Day Learning about Cancer Research at N2CR!

2 June 2024

School’s out but the learning continues! N2CR hosted its very first educational outreach programme, Inspiring Young Mi...

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Research News

METTL8 links mt-tRNA m3C modification to the HIF1α/RTK/Akt axis to sustain GBM stemness and tumorigenicity

20 May 2024

Glioblastoma is the most common and lethal form of adult brain cancer. The presence of cancer stem cells (so-called glio...

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