Improved drug combination design for hepatocellular carcinoma
Hepatocellular carcinoma (HCC) remains difficult to treat due to a lack of effective treatment options. While various drugs have shown promising preclinical results, poor drug combination design results in less […]
Immune pathway upregulation and lower genomic instability distinguish EBVpositive nodal T/NK-cell lymphoma from ENKTL and PTCL-NOS
Primary Epstein-Barr virus (EBV)-positive nodal T/NK-cell lymphoma (PTCL-EBV) is an aggressive and poorly understood disease that occurs mostly in East Asia. In this collaborative study, led by A/Prof Ng Siok […]
TP73, an important gene in Adult T-cell Leukemia/Lymphoma
Adult T-cell leukemia/lymphoma (ATL) is a genetically complex form of blood cancer. In this study led by A/Prof Takaomi Sanda, the authors investigated the roles, functions as well as factors […]
A promising new drug delivery system for cancer
The leakage of chemotherapeutic drugs into tissues other than the tumour can result in adverse side effects. Efforts have been made to devise novel drug delivery methods to improve drug […]
A step towards the ambition of precision oncology in recurrent ovarian cancer
Platinum resistance is a major contributor to ovarian cancer mortality and presents a considerable clinical challenge, necessitating the development of better treatments for platinum-resistant patients. In this editorial, A/Prof. David […]