Pseudogene demethylation activates oncogenes in Hepatocellular carcinoma
Hepatitis B virus (HBV) infection is one of the main causes of Hepatocellular carcinoma (HCC) which is one of leading causes of cancer related deaths globally. Pseudogenes have recently been […]
Fatty acid oxidation inhibits breast cancer cells in animal models
Fatty acids oxidation (FAO) confers Epithelial-to-mesenchymal transition causing enhanced tumorigenicity and drug resistance to cancer cells. This study by N2CR member A/Prof Tam Wai Leong and his team demonstrates that […]
Liver transplantation for metastatic tumours
More than 50% of colorectal cancer patients develop metastases to the liver. Liver resection is considered the only treatment for patients with colorectal liver metastases. This review by A/Prof Glenn […]
Vaccine therapy for nasopharyngeal carcinoma
Epstein-Barr virus (EBV) is associated with nasopharyngeal carcinoma (NPC) and provides a potential target for dendritic cell vaccine therapy. This phase 1 clinical study led by Prof Goh Boon Cher […]