Deciphering antibody sequences

Mar 11, 2025
MD4 level 2 Seminar Room (MD4-02-03E)

Abstract:  

Advances in antibody repertoire sequencing allow for the rapid discovery of many antibody sequences. However, identifying the specificity of these antibodies remains a slow and challenging process, leaving their specificities mostly unknown. This talk will explore the potential to predict antibody targets based on sequences and discuss why this challenge is considered addressable.

 

Biography:  

Dr. Wu is an Assistant Professor of Biochemistry at the University of Illinois Urbana-Champaign. Dr. Wu received his BSc in Biochemistry from the University of Virginia in 2010 and his PhD in Molecular Biology from UCLA in 2015. After his graduate studies, Dr. Wu completed his postdoctoral training at Scripps Research as a Croucher Fellow before starting his own lab in 2020. Dr. Wu’s research, which mainly focuses on virus evolution and antibody response, has been recognized by multiple awards, including NIH New Innovator Award, Michelson Prize, Searle Scholar Award, and Vallee Scholar Award.

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Secondary Members

David ALLEN

Associate Professor​ (Medicine)​ ​

Sophia ARCHULETA

Associate Professor (Medicine)

Yann BOUCHER

Associate Professor (SPH)​

Louis CHAI

Associate Professor​ (Medicine)​

Kaiwen CHEN

Assistant Professor (Micro & Immuno)

CHN'G Jun Hong

Senior Lecturer (Micro & Immuno)

 

LOK Shee Mei

 Professor (Duke-NUS)

Hannah CLAPHAM

Assistant Professor (SPH)

Dale FISHER​

Professor​ (Medicine)​

KOH Cho Yeow

Associate Professor (Medicine)

Raymond LIN

Associate Professor​ (NPHL-NCID)​

LUO Min

Assistant Professor (DBS)

Benoit MALLERET

Assistant Professor (Micro & Immuno)

Matthew TAY

Adjunct Assistant Professor (Biochemistry)

Kevin TAN

Associate Professor​ (Micro & Immuno)​

Adjunct Members

Guillaume CARISSIMO

Assistant Professor​ (A*STAR ID Labs)

Yin Xiang SETOH​

Assistant Professor​ (EHI)​

Marco VIGNUZZI

Associate Professor 
(A*STAR ID Labs)

Primary Members

Sylvie ALONSO​

Associate Professor

John CHEN​

Associate Professor

Vincent CHOW​

Associate Professor​

Justin CHU

Associate Professor​

GAN Yunn Hwen

Associate Professor

HSU Li Yang​

 Professor

Catherine ONG​

Associate Professor

David PATERSON

Professor

Nick PATON​

Professor​

QU Kun

Assistant Professor

SHAM​ Lok To

Associate Professor​

Paul A. TAMBYAH

Professor

TAN Chee Wah

Research Assistant Professor

TAN Yee Joo​

Associate Professor​

Thai TRAN​

Associate Professor​

NAGARAJAN Niranjan

Associate Professor

ZHONG Youjia

Assistant Professor

CHNG Shu Sin

Associate Professor​ (Chemistry)​

MO Yin

Consultant (Medicine) 

Yassine CHERRAK

Assistant Professor

Cheryl LEE Qi En

Assistant Professor ?

CHNG Shu Sin

Associate Professor​ (Chemistry)​

MO Yin

Consultant (Medicine) 

WANG De Yun​

Professor​

TAN Yee Joo​

Associate Professor​