Research Themes
Define molecular and cellular mechanisms of immune-regulation, targets and lead molecules and harness them to design new strategies restoring immune homeostasis to prevent and treat infectious, inflammatory diseases and cancers.
Advance and deliver Innovative immune-based therapies to patients through identification of new cancer targets for antibody or CAR-T therapy, improvement of CAR-T therapy, and development of new vaccines
Team Leads
Prof Nicholas Gascoigne
Coordinator
Key Areas of Research
- CAR-T cells
- T cell activation and signalling
- T cell development
- Microbiome effect on T cell differentiation
A/Prof Liu Haiyan
Coordinator
Key Areas of Research
- Adoptive immunotherapy
- Cancer vaccines
- Tumor microenvironment
- Innate immune cell subsets, including ILCs, NK cells and γδT cells
Team Members
Prof Dario Campana
Key Areas of Research
- Prognostication and monitoring of hematologic malignancies
- Development of practical approaches to enhance the anti-cancer activity of immune cells
A/Prof Herbert Schwarz
Key Areas of Research
- Tumour Immunology
- Cancer vaccines
- Dendritic Cells
- CD137 – CD137 ligand
A/Prof Lina Lim Hsiu Kim
Key Areas of Research
- Annexin-A1
- Macrophages and Dendritic cells in the Tumor microenvironment
- Impact of Stress on cancer and inflammation
Dr Makoto Yawata
Key Areas of Research
- Immunological mechanisms of NK cell responses in cancer and infectious diseases
- Computational characterization of genetic and functional diversification in human NK cell repertoires
- Phenotypes and functions of organ-specific NK cells in health and disease
A/Prof Paul MacAry
Key Areas of Research
- Human Antibody Discovery and Engineering
- Alloantibody
- Dengue Virus Antibodies
A/Prof Zhang Yongliang
Key Areas of Research
- Immune response to infection and cancer
- Signal transduction in cancer development
- Dual-specificity phosphatases (DUSPs)