Introduction of
Who we are
The Immunology Translational Research Programme aims to understand the role of the immune system in health and diseases and its regulation with the goal of enabling discovery and development of more effective immunotherapy, new treatment guidelines and diagnostic tests for patients with disease-specific problems such as autoimmune and airway diseases, cancer, chronic inflammation, infections and organ / tissue transplantation.
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Farewell to A/Prof. Veronique Angeli
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Singleron Seminar (Organized by ITRP Single Cell Genomics Core & Singleron)
Seminar
The cGAMP transporter LRRC8VRAC and the noncanonical STING signaling in antiviral and antitumor immunity
Seminar
Ubiquitination in Cell Death and Tissue Injury
NUSMED ITRP Seminar Series
Basic Research and Translational Medicine in Lupus
Seminar
Intron Retention of DDX39A is a sensor for Myc/Spliceosome program in hepatocellular carcinoma
Seminar
NUS Yong Loo Lin School of Medicine Immunology TRP Research Seminar
Publications
Digitalized organoids: integrated pipelinefor high-speed 3D analysis of organoidstructures using multilevel segmentationand cellular topology
Publications
Molecular basis of Spns1-mediated lysophospholipid transport from the lysosome
Publications
Nation-wide surveillance of tick (Acari: Ixodidae) infestations of humans in Singapore
Publications
Plasticity of cell death pathways ensures GSDMD activation during Yersinia pseudotuberculosis infection
Publications
DUSP6 regulates Notch1 signalling in colorectal cancer
The hallmark of
the programme
Research Team of
Immune Homeostasis
To advance understanding the role of the immune
system in health and diseases and its regulation.
A/Prof Zhang Yongliang
Coordinator
Key Areas of Research
- Immune response to infection and cancer
- Signal transduction in cancer development
- Dual-specificity phosphatases (DUSPs)
Dr Chen Kaiwen
Coordinator
Key Areas of Research
- Innate immunity and inflammation
- Programmed cell death
- Host-pathogen interactions
Research Team of
Immunotherapies
To advance understanding the role of the immune
system in health and diseases and its regulation.
A/Prof Liu Haiyan
Coordinator
Key Areas of Research
- Adoptive immunotherapy
- Cancer vaccines
- Tumor microenvironment
- Innate immune cell subsets, including ILCs, NK cells and γδT cells
Research Team of
The Asian Immunophenotype
and Clinical Investigations
To advance understanding the role of the immune
system in health and diseases and its regulation.
Dr Tay Sen Hee Frank
Coordinator
Key Areas of Research
- Systemic lupus erythematosus
- Nonsteroidal anti-inflammatory drug hypersensitivity
- Immune-related adverse effects
- Neutrophils
- Epigenetics
Dr Makoto Yawata
Coordinator
Key Areas of Research
- Immunological mechanisms of NK cell responses in cancer and infectious diseases
- Computational characterization of genetic and functional diversification in human NK cell repertoires
- Phenotypes and functions of organ-specific NK cells in health and disease
Providing Quality
Core Facilities
Equipped with cutting edge tools at the forefront of technology
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