Introduction of
Who we are
The Immunology Translational Research Programme aims to understand the role of the immune system in health and diseases and its regulation with the goal of enabling discovery and development of more effective immunotherapy, new treatment guidelines and diagnostic tests for patients with disease-specific problems such as autoimmune and airway diseases, cancer, chronic inflammation, infections and organ / tissue transplantation.
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Ticking time bomb? Study on ticks in Singapore calls for greater vigilance
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Happy CNY 2025. Thank you everyone for helping with the hampers.
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Singleron Seminar (Organized by ITRP Single Cell Genomics Core & Singleron)
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NUS Medicine study discovers potential for new colorectal cancer treatment
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Open Discussion Session with Nobel Laureate Sir Richard Roberts
NUSMED ITRP Seminar Series
Basic Research and Translational Medicine in Lupus
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Intron Retention of DDX39A is a sensor for Myc/Spliceosome program in hepatocellular carcinoma
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NUS Yong Loo Lin School of Medicine Immunology TRP Research Seminar
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NUS Yong Loo Lin School of Medicine Immunology TRP Research Seminar
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NUS Yong Loo Lin School of Medicine Immunology TRP Research Seminar
Publications
Molecular basis of Spns1-mediated lysophospholipid transport from the lysosome
Publications
Nation-wide surveillance of tick (Acari: Ixodidae) infestations of humans in Singapore
Publications
Plasticity of cell death pathways ensures GSDMD activation during Yersinia pseudotuberculosis infection
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DUSP6 regulates Notch1 signalling in colorectal cancer
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MFSD7c functions as a transporter of choline at the blood–brain barrier
The hallmark of
the programme
Research Team of
Immune Homeostasis
To advance understanding the role of the immune
system in health and diseases and its regulation.
A/Prof Zhang Yongliang
Coordinator
Key Areas of Research
- Immune response to infection and cancer
- Signal transduction in cancer development
- Dual-specificity phosphatases (DUSPs)
Dr Chen Kaiwen
Coordinator
Key Areas of Research
- Innate immunity and inflammation
- Programmed cell death
- Host-pathogen interactions
Research Team of
Immunotherapies
To advance understanding the role of the immune
system in health and diseases and its regulation.
A/Prof Liu Haiyan
Coordinator
Key Areas of Research
- Adoptive immunotherapy
- Cancer vaccines
- Tumor microenvironment
- Innate immune cell subsets, including ILCs, NK cells and γδT cells
Prof Nicholas Gascoigne
Coordinator
Key Areas of Research
- CAR-T cells
- T cell activation and signalling
- T cell development
- Microbiome effect on T cell differentiation
Research Team of
The Asian Immunophenotype
and Clinical Investigations
To advance understanding the role of the immune
system in health and diseases and its regulation.
Dr Tay Sen Hee Frank
Coordinator
Key Areas of Research
- Systemic lupus erythematosus
- Nonsteroidal anti-inflammatory drug hypersensitivity
- Immune-related adverse effects
- Neutrophils
- Epigenetics
Dr Makoto Yawata
Coordinator
Key Areas of Research
- Immunological mechanisms of NK cell responses in cancer and infectious diseases
- Computational characterization of genetic and functional diversification in human NK cell repertoires
- Phenotypes and functions of organ-specific NK cells in health and disease
Providing Quality
Core Facilities
Equipped with cutting edge tools at the forefront of technology
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