Research Themes
Define molecular and cellular mechanisms of immune-regulation, targets and lead molecules and harness them to design new strategies restoring immune homeostasis to prevent and treat infectious, inflammatory diseases and cancers.
Define molecular and cellular mechanisms of immune-regulation, targets and lead molecules and harness them to design new strategies restoring immune homeostasis to prevent and treat infectious, inflammatory diseases and cancers.
Team Leads
Serene Tan
Admin Lead
Ms Too Chien Tei
Senior Laboratory Manager
Ms Sua Xin Ying
Research Assistant
Prof Alessandro Sette
Center for Autoimmunity and Inflammation
Center for Cancer Immunotherapy
Center for Vaccine Innovation
Prof Peter Preiser
President’s Chair in Biological Sciences
Professor, School of Biological Sciences, NTU
A/Prof Zhang Yongliang
Micro/Immuno
Key Areas of Research
- Immune response to infection and cancer
- Signal transduction in cancer development
- Dual-specificity phosphatases (DUSPs)
Dr Chen Kaiwen
Micro/Immuno
Key Areas of Research
- Innate immunity and inflammation
- Programmed cell death
- Host-pathogen interactions
Dr Benoit Malleret
Micro/Immuno
Key Areas of Research
- Human and zoonotic malaria
- Gut microbiome dysbiosis
- Electron microscopy
Dr Jonathan Lee Wei Jie
Medicine
Key Areas of Research
- Investigating the role of the gut microbiome in gastrointestinal cancers.
- Develop predictive microbial markers and targeted therapies for gastrointestinal cancers.
A/Prof Lina Lim Hsiu Kim
Physiology
Key Areas of Research
- Annexin-A1
- Macrophages and Dendritic cells in the Tumor microenvironment
- Impact of Stress on cancer and inflammation
A/Prof Lu Jinhua
Micro/Immuno
Key Areas of Research
- Cancer vaccines: antigens & adjuvants
- Systemic lupus erythematosus (SLE): alarmins & autoantibodies
- Complement: C1q & C1 proteases
A/Prof Nguyen Nam Long
Biochemistry
Key Areas of Research
- Sphingosine-1-phosphate transport and signaling
- Nutrient transport at blood-brain barrier
- Lysosomal transport pathways for small molecules
- Lysolipid transport and functions
Dr Tay Sen Hee Frank
Medicine
Key Areas of Research
- Systemic lupus erythematosus
- Nonsteroidal anti-inflammatory drug hypersensitivity
- Immune-related adverse effects
- Neutrophils
- Epigenetics
A/Prof Veronique Angeli
Micro/Immuno
Key Areas of Research
- Lymphatic vessel biology and functions
- Lymphedema
- Tissue-resident macrophages
- Cardiovascular and metabolic diseases
Prof Dario Campana
Paediatrics
Key Areas of Research
- Prognostication and monitoring of hematologic malignancies
- Development of practical approaches to enhance the anti-cancer activity of immune cells
A/Prof Herbert Schwarz
Physiology
Key Areas of Research
- Tumour Immunology
- Cancer vaccines
- Dendritic Cells
- CD137 – CD137 ligand
Dr Makoto Yawata
Paediatrics
Key Areas of Research
- Immunological mechanisms of NK cell responses in cancer and infectious diseases
- Computational characterization of genetic and functional diversification in human NK cell repertoires
- Phenotypes and functions of organ-specific NK cells in health and disease
A/Prof Paul MacAry
Micro/Immuno
Key Areas of Research
- Human Antibody Discovery and Engineering
- Alloantibody
- Dengue Virus Antibodies
Dr Amanda Chan Chee Yun
Medicine
Key Areas of Research
- Small fiber neuropathies
- Autonomic disorders
- Neurological sleep disorders
Dr Peh Hong Yong
Pharmacology
Key Areas of Research
- Resolution of inflammation
- Pro-resolving lipid mediators (lipoxins, resolvins, maresins, protectins) and eicosanoids
- Inflammation and inflammaging
- Macrophage efferocytosis
A/Prof Chen Jinmiao
Micro/Immuno
Key Areas of Research
- Single-cell omics, Spatial omics, AI, Immunology.
- Developing novel analytical methods and databases for the integration and analyses of single-cell and spatial omics data.
A/Prof Matthew Edward Cove
Medicine
Key Areas of Research
- Extracorporeal ventilation support device development
- Patient-ventilator interactions in acute respiratory distress syndrome (ARDS)
- Studies and diagnostic development for pneumonia, fever, and sepsis
A/Prof Peter Goon Kin Cho
Medicine
Key Areas of Research
- Virus-associated cancers
- Tumor microenvironment
- Host-virus immunology
- Dermatological science advancements
Dr Anne Beghin
Micro/Immuno
Key Areas of Research
- Mechanobiology, cancer and immunology research
- Organoids, Organ-on-chip, 3D bioprinter
- Microscopy, AI, image analysis
- Microgravity and Space environnements (regolith, radiation, microgravity) effect on human tissue homeostasis
A/Prof Thai Tran
Physiology
Key Areas of Research
- Respiratory Pathophysiology
- Asthma
- Lung Cancer
- Cellular Physiology
A/Prof Gan Yunn Hwen
Biochemistry
Key Areas of Research
- Novel strategies for targeting multidrug resistant enteric bacteria
- Multidrug resistance plasmid transmission in clinical Gram-negative bacteria
A/Prof Sylvie Alonso
Micro/Immuno
Key Areas of Research
- Host-pathogen interactions in order to identify and understand the role of host and viral factors in the fitness and virulence of pathogens
A/Prof Tan Yee Joo
Micro/Immuno
Key Areas of Research
- Molecular Virology
- Viral-host Interactions
- Neutralising antibodies
- Influenza Virus
Team Members
Prof Alessandro Sette
Center for Autoimmunity and Inflammation
Center for Cancer Immunotherapy
Center for Vaccine Innovation
Dr Amanda Chan Chee Yun
Medicine
Key Areas of Research
- Small fiber neuropathies
- Autonomic disorders
- Neurological sleep disorders
Dr Anne Beghin
Micro/Immuno
Key Areas of Research
- Mechanobiology, cancer and immunology research
- Organoids, Organ-on-chip, 3D bioprinter
- Microscopy, AI, image analysis
- Microgravity and Space environnements (regolith, radiation, microgravity) effect on human tissue homeostasis
Dr Benoit Malleret
Micro/Immuno
Key Areas of Research
- Human and zoonotic malaria
- Gut microbiome dysbiosis
- Electron microscopy
A/Prof Chen Jinmiao
Micro/Immuno
Key Areas of Research
- Single-cell omics, Spatial omics, AI, Immunology.
- Developing novel analytical methods and databases for the integration and analyses of single-cell and spatial omics data.
Dr Chen Kaiwen
Micro/Immuno
Key Areas of Research
- Innate immunity and inflammation
- Programmed cell death
- Host-pathogen interactions
Prof Dario Campana
Paediatrics
Key Areas of Research
- Prognostication and monitoring of hematologic malignancies
- Development of practical approaches to enhance the anti-cancer activity of immune cells
A/Prof Gan Yunn Hwen
Biochemistry
Key Areas of Research
- Novel strategies for targeting multidrug resistant enteric bacteria
- Multidrug resistance plasmid transmission in clinical Gram-negative bacteria
A/Prof Herbert Schwarz
Physiology
Key Areas of Research
- Tumour Immunology
- Cancer vaccines
- Dendritic Cells
- CD137 – CD137 ligand
Dr Jonathan Lee Wei Jie
Medicine
Key Areas of Research
- Investigating the role of the gut microbiome in gastrointestinal cancers.
- Develop predictive microbial markers and targeted therapies for gastrointestinal cancers.
A/Prof Lina Lim Hsiu Kim
Physiology
Key Areas of Research
- Annexin-A1
- Macrophages and Dendritic cells in the Tumor microenvironment
- Impact of Stress on cancer and inflammation
A/Prof Lu Jinhua
Micro/Immuno
Key Areas of Research
- Cancer vaccines: antigens & adjuvants
- Systemic lupus erythematosus (SLE): alarmins & autoantibodies
- Complement: C1q & C1 proteases
Dr Makoto Yawata
Paediatrics
Key Areas of Research
- Immunological mechanisms of NK cell responses in cancer and infectious diseases
- Computational characterization of genetic and functional diversification in human NK cell repertoires
- Phenotypes and functions of organ-specific NK cells in health and disease
A/Prof Matthew Edward Cove
Medicine
Key Areas of Research
- Extracorporeal ventilation support device development
- Patient-ventilator interactions in acute respiratory distress syndrome (ARDS)
- Studies and diagnostic development for pneumonia, fever, and sepsis
A/Prof Nguyen Nam Long
Biochemistry
Key Areas of Research
- Sphingosine-1-phosphate transport and signaling
- Nutrient transport at blood-brain barrier
- Lysosomal transport pathways for small molecules
- Lysolipid transport and functions
A/Prof Paul MacAry
Micro/Immuno
Key Areas of Research
- Human Antibody Discovery and Engineering
- Alloantibody
- Dengue Virus Antibodies
Dr Peh Hong Yong
Pharmacology
Key Areas of Research
- Resolution of inflammation
- Pro-resolving lipid mediators (lipoxins, resolvins, maresins, protectins) and eicosanoids
- Inflammation and inflammaging
- Macrophage efferocytosis
A/Prof Peter Goon Kin Cho
Medicine
Key Areas of Research
- Virus-associated cancers
- Tumor microenvironment
- Host-virus immunology
- Dermatological science advancements
Prof Peter Preiser
President’s Chair in Biological Sciences
Professor, School of Biological Sciences, NTU
Serene Tan
Admin Lead
Ms Sua Xin Ying
Research Assistant
A/Prof Sylvie Alonso
Micro/Immuno
Key Areas of Research
- Host-pathogen interactions in order to identify and understand the role of host and viral factors in the fitness and virulence of pathogens
A/Prof Tan Yee Joo
Micro/Immuno
Key Areas of Research
- Molecular Virology
- Viral-host Interactions
- Neutralising antibodies
- Influenza Virus
Dr Tay Sen Hee Frank
Medicine
Key Areas of Research
- Systemic lupus erythematosus
- Nonsteroidal anti-inflammatory drug hypersensitivity
- Immune-related adverse effects
- Neutrophils
- Epigenetics
A/Prof Thai Tran
Physiology
Key Areas of Research
- Respiratory Pathophysiology
- Asthma
- Lung Cancer
- Cellular Physiology
Ms Too Chien Tei
Senior Laboratory Manager
A/Prof Veronique Angeli
Micro/Immuno
Key Areas of Research
- Lymphatic vessel biology and functions
- Lymphedema
- Tissue-resident macrophages
- Cardiovascular and metabolic diseases
A/Prof Zhang Yongliang
Micro/Immuno
Key Areas of Research
- Immune response to infection and cancer
- Signal transduction in cancer development
- Dual-specificity phosphatases (DUSPs)