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introduction
who we are
The Cardiovascular-Metabolic Disease Translational Research Programme (CVMD-TRP), NUS Yong Loo Lin school of Medicine is dedicated to advancing the understanding of cardiovascular metabolic diseases and developing innovative therapies that can make a real difference in the lives of patients. We are mobilising our collective talent and resources for comprehensive research – encompassing molecules, DNA, RNA, cells, clinical trials, computational and data science, implementation, behavioural and social science.
primary objective
Tackling heart disease comprehensively
- Stem Cells
- CV Immunology
- Genomics
- Smooth Muscle Cells
- Pre-clinical Models
- Mitochondria
- CRISPR Gene Editing
- Clinical Trials
- Implementation & Behavioural Science
- Digital Health
coreS & capabilities
dedicated to our research, collaboration & innovation
Mark Chan
CVMD TRP Deputy Director
Associate Professor
Key Areas of Research
- Cardiovascular Drug Discovery in Atherosclerosis & Myocardial Infarction
- Biomarker Discovery in Chronic & Acute Coronary Syndrome
- Outcomes & Systems of Care in Acute Coronary Syndrome
Koh Cho Yeow
CVMD TRP Research Director
Research Assistant Professor
Key Areas of Research
- Structure-function Relationship Studies
- Drug / Target / Probe Discovery
- Venom / Salivary Proteins & Peptides
Vitaly A. Sorokin
Assistant Professor
Key Areas of Research
- Vascular Smooth Muscle Cells
- Cardiovascular Single Cell Analysis
Wong Lee Lee
Research Assistant Professor
Key Areas of Research
- MicroRNA as diagnostic & Prognostic biomarker in heart failure
- Role of microRNA & Circular RNA in heart failure
Arthur Mark Richards
Visiting Professor
Key Areas of Research
- Neurohormonal physiology and pathophysiology in cardiovascular health and disease
- Heart Failure
- Acute coronary syndromes
- Hypertension
- Vasoactive hormones
- The Cardiac Natriuretic Peptides
Chester Drum
Associate Professor
Key Areas of Research
- Mass spectroscopy for precision medicine
- New forms of novel biomarker detection & multi-omics analyses of large patient cohorts
Roger Foo
CVMD TRP Director
Zayed bin Sultan Al Nahyan Professor of Medicine
Key Areas of Research
- Clinical Genomics
- Chromatin Architecture
- Cardiovascular Epigenetics & Cell States
- Long Non-coding RNA
- Clinical Genomics
Shu Ye
Professor
Key Areas of Research
- Genetic basis & mechanisms of cardiovascular diseases
- Pathogenesis of atherosclerosis
- Identification of therapeutic targets
Chen Ching Kit
Assistant Professor
Key Areas of Research
- Epigenetics in congenital heart disease
- Preclinical models of congenital heart disease
- Assessment of fetal cardiac function
- Infant heart transplantation
- Myocardial fibrosis & magnetic resonance mapping
Jiang Jianming
Assistant Professor
Key Areas of Research
- Understanding how the deregulated factors contribute to the development of cardiovascular disease using cutting-edge technologies
- Identifying novel regulators that reinstate the regenerative potential of cardiomyocytes in the postnatal mammalian heart
Heng Chew Kiat
Research Associate Professor
Key Areas of Research
- Genetic epidemiology of cardiovascular diseases
- Functional characterization of novel proteins identified from genome wide association studies (GWAS) of coronary artery disease
Matthew Ackers-Johnson
Research Assistant Professor
Key Areas of Research
- Tissue & hPSC derived cell models
- Cell-cell communication
- Single cell sequencing
Koh Cho Yeow
CVMD TRP Research Director
Research Assistant Professor
Key Areas of Research
- Structure-function Relationship Studies
- Drug / Target / Probe Discovery
- Venom / Salivary Proteins & Peptides
Vitaly A. Sorokin
Assistant Professor
Key Areas of Research
- Vascular Smooth Muscle Cells
- Cardiovascular Single Cell Analysis
Matthew Ackers-Johnson
Research Assistant Professor
Key Areas of Research
- Tissue & hPSC derived cell models
- Cell-cell communication
- Single cell sequencing
Roshni Rebecca Singaraja
Research Assistant Professor
Key Areas of Research
- Cardiovascular & metabolic diseases
- Target identification (human genetics) & validation
Veronique Angeli
Associate Professor
Key Areas of Research
- Lymphatic vessels & LYVE+ macrophage biology & function in resolution of inflammation & cardiovascular disease
Wang Jiongwei
Research Assistant Professor
Key Areas of Research
- Cardiovascular immunology
- Heart failure (preclinical)
- Extracellular vesicles
- Nanomedicine in cardiometabolic disease (myocardial infarction, atherosclerosis, NAFLD/NASH)
Roger Foo
CVMD TRP Director
Zayed bin Sultan Al Nahyan Professor of Medicine
Key Areas of Research
- Clinical Genomics
- Chromatin Architecture
- Cardiovascular Epigenetics & Cell States
- Long Non-coding RNA
- Clinical Genomics
Wang Wenru
Professor
Key Areas of Research
- Chronic illness and Long-Term Care
- Cardiovascular Health & Cardiac Rehabilitation
- Diabetes Management
- Active Aging
- mHealth
- Tele-medicine
- AI
Mark Dhinesh Muthiah
Assistant Professor
Key Areas of Research
- Fatty liver disease
- Hepatology
Dan Yock Young
Associate Professor
Key Areas of Research
- Fatty liver disease
- Hepatology
Mayank Dalakoti
Associate Consultant Cardiologist (NUHS NCSP2.0 Awardee)
Mark Chan
CVMD TRP Deputy Director
Associate Professor
Key Areas of Research
- Cardiovascular Drug Discovery in Atherosclerosis & Myocardial Infarction
- Biomarker Discovery in Chronic & Acute Coronary Syndrome
- Outcomes & Systems of Care in Acute Coronary Syndrome
Koh Cho Yeow
CVMD TRP Research Director
Research Assistant Professor
Key Areas of Research
- Structure-function Relationship Studies
- Drug / Target / Probe Discovery
- Venom / Salivary Proteins & Peptides
Ronald Lee Chi Hang
Professor
Key Areas of Research
- Relationship between obstructive sleep apnea and cardiovascular disease
- Obstructive sleep apnea therapeutics on cardiovascular outcomes
- Use of Artificial Intelligence in the diagnosis of obstructive sleep apnea
- Epidemiology of obstructive sleep apnea in Asia
Sia Ching Hui
Associate Consultant Cardiologist
Senior Lecturer (Nusmed Junior Academic Fellow)
Mark Chan
CVMD TRP Deputy Director
Associate Professor
Key Areas of Research
- Cardiovascular Drug Discovery in Atherosclerosis & Myocardial Infarction
- Biomarker Discovery in Chronic & Acute Coronary Syndrome
- Outcomes & Systems of Care in Acute Coronary Syndrome
Christopher Chen
Associate Professor
Key Areas of Research
- Cognitive Impairment
- Dementia
- Cerebrovascular Disease
- Neurodegenerative Disease
- Translational research & Clinical trials in Stroke & Dementia
Theodoros Kofidis
Visiting Professor
Key Areas of Research
- MedTech & Innovation
Chester Drum
Associate Professor
Key Areas of Research
- Mass spectroscopy for precision medicine
- New forms of novel biomarker detection & multi-omics analyses of large patient cohorts
Roger Foo
CVMD TRP Director
Zayed bin Sultan Al Nahyan Professor of Medicine
Key Areas of Research
- Clinical Genomics
- Chromatin Architecture
- Cardiovascular Epigenetics & Cell States
- Long Non-coding RNA
- Clinical Genomics
Mark Chan
CVMD TRP Deputy Director
Associate Professor
Key Areas of Research
- Cardiovascular Drug Discovery in Atherosclerosis & Myocardial Infarction
- Biomarker Discovery in Chronic & Acute Coronary Syndrome
- Outcomes & Systems of Care in Acute Coronary Syndrome
Shu Ye
Professor
Key Areas of Research
- Genetic basis & mechanisms of cardiovascular diseases
- Pathogenesis of atherosclerosis
- Identification of therapeutic targets
Dennis Wang
Principal Investigator (Bioinformatics), SICS, A*STAR
Liu Boxiang
Assistant Professor, Department of Pharmacy, NUS
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make breakthroughs in cardiovascular diseases.
MD6, 08-01T
