Lung Disease Research Laboratory

Publications

Book Chapters

Genomic and Non-Genomic Effects of Glucocorticoids in Respiratory Diseases - Advances in Pharmacology Volume 98 (Elsevier)

Middleton's Allergy - C Principles and Practices (Elsevier) 8th Edition

Airway Smooth Muscle Function in Asthma: Extracellular Matrix and Airway (page 730-738)

Selected Journal Publications

  1. Chun YY, Tan KS, Yu L, Pang M, Wong MHM, Nakamoto R, Chua WZ, Huee-Ping Wong A, Lew ZZR, Ong HH, Chow VT, Tran T, Yun Wang D, Sham LT. Proc Natl Acad Sci U S A. 2023 Mar 28;120(13):e2213584120. doi: 10.1073/pnas.2213584120. Epub 2023 Mar 21.PMID: 36943879
  2. Qiao YK, Yan Y, Tan KS, Tan SL, Seet JE, Arumugam TV, Chow VTK, Wang DY* and Tran T*. CD151, a novel host factor of nuclear export signaling in influenza virus infection. J. Allergy Clin. Immunol. 2018; 141 (5): 1799-1817 [Impact Factor (IF) = 13.258, 3 citations]
  3. Qiao YK, Tam JKC, Tan SSL, Tai AYK, Chin CY, Stewart AG, Ashman L, Sekiguchi K, Ashman L, Langenback S, Stelmack G, Halayko AJ, Tran T*. CD151, a laminin receptor showing increased expression in asthmatic patients, contributes to airway hyperresponsiveness through calcium signalling. JACI. 2017; 139 (1):82-92 [IF = 13.258, 4 citations]
  4. Yan Y, Tan KS, Li CW, Tran T, Chao SS, Sugrue RJ, Shi L, Chow VT and Wang DY. Human nasal epithelial cells derived from multiple subjects exhibit differential responses to H3N2 influenza infection in vitro. JACI. 2016; 138(1):276-281 [IF = 13.258, 9 citations]
  5. Ward JE, Harris T, Bamford T, Mast A, Pain MC, Robertson C, Smallwood D, Tran T, Wilson J and Stewart AG. Proliferation is Not Increased in Airway Myofibroblasts Isolated from Asthmatics. Eur. Respir. J. 2008; 32: 362371. [IF=12.242, 48 citations]
  6. An S, Bates J, Brown R, Brusasco V, Chitano P, Deng LH, Eidelman D, Fabry B, Fredberg J, Gerthoffer WT, Gosens R, Gunst S, Halayko AJ, Irvin, James A, Janssen L, King G, Lauzon A-M, Ludwig M, Lutchen K, Maksym G, Martin J, Mijailovich S, Mitchell H, Mitchell R, Mitzner W, Murphy T, Pare P, Pellegrino R, Seow C, Smith P, Solway J, Stephens N, Sterk P, Stewart A, Tang D, Tepper R, Tran T & Wang L. Airway smooth muscle dynamics: a common pathway of airway obstruction in asthma. Eur Resp J; 2007; 29 (5): 834-860. [IF=12.242, 377 citations]
  7. Cheong DHJ, Arfuso F, Sethi G, Wang L, Hui KM, Kumar AP, Tran T*. Cancer Lett. 2018; 422: 1-8 [IF = 6.491, citations = 2]
  8. Tan KS, Yan Y, Koh WLH, Li L, Choi H., Tran T, Sugrue R, Wang DY, Chow VTK. Comparative Transcriptomic and Metagenomic Analyses of Influenza Virus-Infected Nasal Epithelial Cells from Multiple Individuals Reveal Specific Nasal-Initiated Signature. Front. Microbiol. 2018; (in press Nov 2018) https://doi.org/10.3389/fmicb.2018.02685. [IF = 4.019]
  9. Teoh CM, Tan SSL, Tran T*. Integrins as therapeutic targets for respiratory diseases. Curr. Mol. Med. 2015; 15: 1-21 [IF = 4.476, citations = 6]
  10. Tan SSL, Ong B, Cheng C, Ho WE, Tam KC, Stewart AG, Harris T, Wong WSF and Tran T*. The Antimalarial Drug Artesunate Inhibits Primary Human Cultured Airway Smooth Muscle Cell Proliferation. Am. J. Respir. Cell Mol. Biol. 2014; 50(2): 451-458. [IF=3.79, citations = 16]
  11. Tran T*, Teoh CM, Tam KC, Qiao YK, Chin CY, Chong OK, Stewart AG, Harris T, Wong WSF, Guan SP, Leung B, Gerthoffer WT, Unruh H and Halayko AJ. Laminin Drives Survival Signals to Promote a Contractile Smooth Muscle Phenotype and Airway Hyperreactivity. FASEB J. 2013; 27(10): 3991-4003. [IF=5.595, citations = 21]
  12. Teoh CM, Tam KC and Tran T*. Integrin and GPCR Crosstalk in the Regulation of ASM contraction Signaling in Asthma. J. of Allergy. 2012; 4(3):183-197. [IF=N/A, citations = 12]
  13. Teoh CM, Tam KC and Tran T*. Ethical Issues Using Bronchial Biopsies for Asthma. Res. Asian Bioethics Rev. 2012; 9. [IF=N/A]
  14. Dekkers BGJ, Schaafsma D, Tran T, Zaagsma J and Meurs H. Insulin-induced Laminin Expression Promotes a Hypercontractile Airway Smooth Muscle Phenotype. Am. J. Respir. Cell Mol. Biol. 2009; 41 (4): 494-504. [IF=3.79, citations = 70]
  15. Hirota JA, Nguyen TTB, Schaafsma D, Sharma P and Tran T*. Airway Smooth Muscle in Asthma: Phenotype Plasticity and Function. Pulm. Pharmacol. Ther. 2009; 22(5): 370-378. [IF=2.406, , citations = 69]
  16. Gosens R, Mutawe M, Martin S, Basu S, Bos ST, Tran T and Halayko AJ. Caveolae and Caveolins in the Respiratory System. Curr. Mol. Med. 2008; 8 (8): 741-753. [IF=4.4, citation = 53]
  17. Sharma P, Tran T, Stelmack G, McNeill K, Gosens R, Mutawe M, Unruh H, Gerthoffer WT and Halayko AJ. Expression of the Dystrophin-glycoprotein Complex is a Marker for Human Airway Smooth Muscle Phenotype Maturation. Am. J. Physiol. Lung Cell. Mol. Physiol. 2008; 294 (1): L57-68. [IF=4.721, citation = 38]
  18. Halayko AJ, Tran T and Gosens R. Phenotype and Functional Plasticity of Airway Smooth Muscle: Role of Caveolae and Caveolins. Proc. Am. Thorac. Soc. 2008; 5 (1): 80-88. [IF=5.77, citation = 89]
  19. Tran T, Blackie-Ens K, Rector E, Stelmack G, McNeill K, Tarone G, Gerthoffer WT, Unruh H and Halayko AJ. Laminin-Binding Integrin alpha 7 is Required for Contractile Phenotype Expression by Human Airway Myocytes. Am. J. Respir. Cell Mol. Biol. 2007; 37 (6): 668-680. [IF=3.79, citation = 48]
  20. Tran T, Gosens R and Halayko AJ. Effects of Extracellular Matrix and Integrin Interactions on Airway Smooth Muscle Cell Phenotype and Function: It takes Two to Tango! Curr. Rev. Respir. Med. 2007; 3 (3): 193-205. [IF=N/A, citation = 9]
  21. Tran T and Halayko AJ. Extracellular Matrix and Airway Smooth Muscle Interactions: A Target for Modulating Airway Wall Remodelling and Hyperresponsiveness? Can. J. Physiol. Pharmacol. 2007; 8 (7): 666-671. [IF=2.21, citation 34]
  22. Tran T, McNeill K, Gerthoffer WT, Unruh H and Halayko AJ. Endogenous Laminin is Required for Human Airway Smooth Muscle Cell Maturation. Respir. Res. 2006; 7: 117. [IF=3.64]
  23. Halayko AJ, Tran T, Ji SY, Yamasaki A and Gosens R. Airway Smooth Muscle Phenotype and Function: Interactions with Current Asthma Therapies. Curr. Drug Targets 2006; 7:525-540. [IF=5.067]
  24. Tran T, Fernandes DJ, Schuliga M, Harris T, Landells L and Stewart AG. Stimulus-Dependent GlucocorticoidResistance of GM-CSF Production in Human Cultured Airway Smooth Muscle. Br. J. Pharmacol. 2005; 145: 123-131. [IF=5.067]
  25. Fernandes DJ, Ravenhall CE, Harris T, Tran T, Vlahos R and Stewart AG. Contribution of the p38MAPK Signaling Pathway to Proliferation in Human Cultured Airway Smooth Muscle Cells is Mitogen-Specific. Br. J. Pharmacol. 2004; 142: 1182-1190. [IF=5.067]
  26. Tran T and Stewart AG. Protease-Activated Receptor (PAR)-Independent Growth and Pro- Inflammatory Actions of Thrombin on Human Cultured Airway Smooth Muscle. Br. J. Pharmacol. 2003; 138: 865-875. [IF=5.067]