The overarching research focus of the TT laboratory is in the investigation of how the microenvironment (laminin, an extracellular matrix protein and its adaptor protein, CD151) interacts with cells of the lung and how dysregulation of this interaction contributes to lung disease pathophysiology, in particular asthma, respiratory infections and lung cancer. The long-term goal of our research is to identify novel therapeutic targets for these diseases.
Our laboratory has two major areas of research focus: