Prof LEE Eng Hin
Academic Appointments:
- Emeritus Professor
Department of Orthopaedic Surgery
Yong Loo Lin School of Medicine
National University of Singapore
Clinical Appointments:
- Emeritus Consultant
Division of Paediatric Orthopaedics
Department of Orthopaedic Surgery,
National University Hospital
Other Appointments
- Senior Fellow
Agency for Science, Technology and Research
- Senior Advisor
Division of Graduate Medical Studies
Yong Loo Lin School of Medicine
National University of Singapore, Singapore
Qualifications
- M.D., University of Western Ontario, Canada
- F.R.C.S., (C) Orthopaedic Surgery, Canada
- F.A.M.S., (Orthopaedics), Singapore
- F.R.C.S., (Edin) Ad Hominem
- F.R.C.S., (Glas) Ad Eundem
Awards and Prizes
- World’s Top 2% Scientists, Stanford University, USA, 2020, 2021, 2022, 2023
- Outstanding Clinician Mentor Award
- Outstanding Researcher Award, NUS
- Outstanding Researcher Award, YLL School of Medicine, NUS
- The Public Service Medal (PBM)
- The President's Social Service Award
- The Public Administration Medal (Silver)
- Lee Foundation –NHG Lifetime Achievement Award
- Emeritus Consultant, National University Health System
Research Areas of Interests
Musculoskeletal Tissue Engineering
- Platform technologies
- Cell and tissue culture and expansion
- Stem cell biology: characterization and differentiation of mesenchymal stem cells
- Biomaterials: biodegradable scaffolds for hard and soft tissues
- Matrix biology and biomolecules
- Translational research
- Repair and regeneration of physis
- Repair and regeneration of articular cartilage
- Tissue engineer ligaments and tendons
Paediatric Orthopaedics & Rehabilitation
- Neuromuscular Disorders (especially Gait Analysis)
- Congenital deformities of spine and extremities
- Orthopaedic trauma in children (especially physeal injuries)
Selected Research Projects
- Generating a high quality immortal mesenchymal stem cell line for chondrogenesis
- Modeling growth plate function with bone marrow derived mesenchymal stem cells to develop improved treatments for growth plate defects in children.
- Development of xeno-/serum free medium to improve the safety and quality of human chondrocytes culture for clinical autologous chondrocyte implantation
- Chondrogenic differentiation of human stem cells: Characterising and defining the cellular and molecular mechanisms and the establishment of stable cellular phenotypes for cartilage regeneration
- The study of gene-enhanced bone marrow mesenchymal stem cells for articular cartilage repair in pig model