Lee, Eng Hin – Department of Orthopaedic Surgery, National University of Singapore

Emeritus Prof LEE Eng Hin

Academic Appointment:

Emeritus Professor
Department of Orthopaedic Surgery
Yong Loo Lin School of Medicine
National University of Singapore

Clinical Appointments

Emeritus Consultant
Division of Paediatric Orthopaedics
Department of Orthopaedic Surgery,
National University Hospital

Other Appointments

Senior Fellow
Agency for Science, Technology and Research

Senior Advisor
Division of Graduate Medical Studies
Yong Loo Lin School of Medicine
National University of Singapore, Singapore

Qualifications

M.D., University of Western Ontario, Canada
F.R.C.S., (C) Orthopaedic Surgery, Canada
F.A.M.S., (Orthopaedics), Singapore
F.R.C.S., (Edin) Ad Hominem
F.R.C.S., (Glas) Ad Eundem

Awards and Prizes

World’s Top 2% Scientists, Stanford University, USA, 2020, 2021, 2022, 2023
Outstanding Clinician Mentor Award
Outstanding Researcher Award, NUS
Outstanding Researcher Award, YLL School of Medicine, NUS
The Public Service Medal (PBM)
The President’s Social Service Award
The Public Administration Medal (Silver)
Lee Foundation –NHG Lifetime Achievement Award
Emeritus Consultant, National University Health System

Research Areas of Interests

Musculoskeletal Tissue Engineering

Platform technologies

Cell and tissue culture and expansion
Stem cell biology: characterization and differentiation of mesenchymal stem cells
Biomaterials: biodegradable scaffolds for hard and soft tissues
Matrix biology and biomolecules

Translational research

Repair and regeneration of physis
Repair and regeneration of articular cartilage
Tissue engineer ligaments and tendons

Paediatric Orthopaedics & Rehabilitation

Neuromuscular Disorders (especially Gait Analysis)
Congenital deformities of spine and extremities
Orthopaedic trauma in children (especially physeal injuries)

Selected Research Projects

Generating a high quality immortal mesenchymal stem cell line for chondrogenesis
Modeling growth plate function with bone marrow derived mesenchymal stem cells to develop improved treatments for growth plate defects in children.
Development of xeno-/serum free medium to improve the safety and quality of human chondrocytes culture for clinical autologous chondrocyte implantation
Chondrogenic differentiation of human stem cells: Characterising and defining the cellular and molecular mechanisms and the establishment of stable cellular phenotypes for cartilage regeneration
The study of gene-enhanced bone marrow mesenchymal stem cells for articular cartilage repair in pig model

Emeritus Prof Lee Eng Hin’s Publication list at NUS Discovery