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Associate Professor Victor Koh

Lead, Community Eye Care, Centre for Innovation and Precision Eye Health
Head of Department, Ophthalmology, National University Hospital
Head of Department, Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore
Consultant Ophthalmologist, Department of Ophthalmology, National University Hospital
Associate Professor, Yong Loo Lin School of Medicine, National University of Singapore

MBBS, MMed (Oph), MRCSEd, MSc, FAMS

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Research Interests and Achievements

The common theme to the 3 key focus of my research is centered on down-stream translation of novel bench-to-bedside research involving glaucoma diagnostics and therapeutics. The scope of my research covers an end-to-end loop from early detection of glaucoma in the community followed by individualized diagnostic work-up in the tertiary ophthalmic practice which leads to latest evidence-based treatment and ultimately back to the community for follow-up. This requires a unique combination of clinical training as an ophthalmologist and an innovator trained in commercialization pathways.

First, the NUS Summit Program in Innovation (SPIN) is the catalyst in decentralization of glaucoma screening/diagnosis in the community. Second, our novel Anterior Segment OCT imaging algorithms would individualize diagnosis and promote precision medicine in angle closure glaucoma management. Third, the development of novel glaucoma therapeutics followed by clinical trials to provide proof-of-concept evidence of efficacy and safety.


Selected Publications

  • Zheng C, Koh V, Bian F, Li L, Xie X, Wang Z, Yang J, Chew PTK, Zhang M Semi-supervised generative adversarial networks for closed-angle detection on anterior segment optical coherence tomography images: an empirical study with a small training dataset. Ann Transl Med. 2021 Jul;9(13):1073. https://doi.org/10.21037/atm-20-7436
  • Ong CW, Tan MCJ, Lam M, Koh V. Applications of Extended Reality in Ophthalmology: Systematic Review. J Med Internet Res. 2021 Aug 19;23(8):e24152. https://doi.org/10.2196/24152
  • Ferraz DA, Sim DA, Belfort Junior R, Koh V. Portable Devices in Ophthalmology. Arq Bras Oftalmol. 2020 Nov-Dec;83(6):566-568. https://doi.org/10.5935/0004-2749.20200111
  • Jeyabal P, Tan C, Koh V. Survey of General Practitioners on Tele-Ophthalmology Practice in Singapore. Ann Acad Med Singap. 2020 Sep;49(9):712-716.
  • Pham TH, Devalla SK, Ang A, Soh ZD, Thiery AH, Boote C, Cheng CY, Girard MJA, Koh V. Deep learning algorithms to isolate and quantify the structures of the anterior segment in optical coherence tomography images. Br J Ophthalmol. 2021 Sep;105(9):1231-1237. https://doi.org/10.1136/bjophthalmol-2019-315723
  • Lai Y, Wu Y, Chai C, Yen CC, Ho Y, Eng TC, Jain P, Koh V. The Effect of Patient Education and Telemedicine Reminders on Adhernece to Eye Drops for Glaucoma. Ophthalmol Glaucoma. 2020 Sep-Oct;3(5):369-376. https://doi.org/10.1016/j.ogla.2020.05.005
  • Tong W,Romero M, Lim V, Loon SC, Suwandono ME, Shuang Y, Di X, Kanagasingam Y, Koh V. Reliability of Graders and Comparison with an Automated Algorithm for Vertical Cup-Disc Ratio Grading in Fundus Photographs. Ann Acad Med Singapore. 2019 Sep;48(9):282-289.
  • Koh V, Keshtkaran MR, Hernstadt D, Aquino MCD, Chew PT, Sng C. Predicting the outcome of laser peripheral iridotomy for primary angle closure suspect eyes using anterior segment optical coherence tomography. Acta Ophthalmol. 2019 Feb;97(1):e57-e63. https://doi.org/10.1111/aos.13822
  • Koh V, Tham YC, Cheung CY, Mani B, Wong TY, Aung T, Cheng CY. Diagnostic accuracy of macular ganglion cell-inner plexiform layer thickness for glaucoma detection in a population-based study: Comparison with optic nerve head imaging parameters. PLoS One. 2018 Jun 26;13(6):e0199134. https://doi.org/10.1371/journal.pone.0199134

Collaborations

View more details on the collaborations here