Our Achievements
Vincenzo Sorrentino selected to join the EMBO Global Investigator Network
Congratulations to Asst Prof Vincenzo Sorrentino on being selected as one of 11 scientists to join the prestigious EMBO Global Investigator Network!
Sorrentino Lab Wins Poster Awards at HLM2025
Dr Sanjay Kumar and Sandra Jose received the Best Poster Presentation Award and runner up respectively, in recognition of the quality, originality, and impact of their research at the Healthy Longevity & Medicine (HLM2025) Conference. Their work exemplifies the innovative and rigorous science being pursued within the lab.
Poster Award at Global Conference on Gerophysics 2025
We congratulate Trina on winning the Best Poster Award at the Global Conference on Gerophysics (GCGP), held on 5-6 March 2025. The award recognizes the quality, originality, and impact of her research presented at the conference.
Best Flash Talk Presentation at Models of Physiology and Disease Symposium
We congratulate Trina on receiving the Best Flash Talk Presentation Award at the 14th Models of Physiology and Disease Symposium, held from 24-26 September 2025. This recognition highlights the clarity and scientific significance of her work.
Advances in NAD⁺ Biology and Therapeutic Strategies
A review from Prof Sorrentino and his team members from NUS and Amsterdam UMC outlines the advances in mechanisms of NAD+ metabolism,its modulation of mitochondrial function via compound-based strategies, and status of clinical translation of NAD+ therapeutics.
Link to Publication: https://www.nature.com/articles/s44324-025-00067-0#Abs1
NNMT in Kidney Disease Progression
A recent study by Prof. Sorrentino and his team members uncovers the pro-aging role of nicotinamide N-methyltransferase (NNMT) in driving tubular cell senescence and fibrosis in kidney disease. The findings position NNMT as a promising therapeutic target for slowing CKD progression through metabolic and epigenetic modulation.
Link to Publication: https://www.biorxiv.org/content/10.1101/2025.01.06.631437.abstract
Integrative View of Longevity Biomarkers
Prof. Sorrentino and his team members discusses the molecular drivers of human longevity, from metabolic regulators and biomarkers to emerging biological clocks and synthesizes integrative strategies for promoting healthy aging through precision interventions.
Link to Publication: https://www.mdpi.com/1422-0067/25/12/6793
NAD⁺ Metabolism and Renal Aging
A study by Prof Sorrentino and his team members explores how disruptions in NAD⁺ metabolism accelerate kidney aging and contribute to chronic kidney disease. The work highlights the therapeutic potential of restoring NAD⁺ homeostasis to protect renal function and delay age-related decline.
Link to Publication: https://www.mdpi.com/2073-4409/12/1/21
