MILD

Microneedle Pattern

Smart Mushroom-Inspired Imprintable and Lightly Detachable
(MILD) Microneedle Pattern

the mushroom-like structure

allows the MILD system to be easily pressed
  • Into the skin and detach from the patch base
  • Acting as a “tattoo” to record the vaccine counts in situ without any storage equipment
  • Offering quick accessibility and effortless readout
  • Saves great deals of valuable time
  • Saves energy for both patients and health professionals
After loading, SARS-CoV-2 virus-based

vaccines are inactivated

MILD system induces high level of antibody against SARS-CoV-2 receptor binding domain (RBD) in vivo without eliciting systemic toxicity and local damage
Overall, this smart delivery platform serves as a promising carrier to improve COVID-19 vaccination efficacy through its dual capabilities of vaccine delivery and in situ data storage, thus exhibiting great potential to aid in containing COVID-19 pandemic or a resurge.