A genetic engineering strategy for editing near-infrared-II fluorophores.
![](https://medicine.nus.edu.sg/trp/nanomedicine/wp-content/uploads/sites/9/2022/05/41467_2022_30304_Fig6_HTML.webp)
Abstract The second near-infrared (NIR-II) window is a fundamental modality for deep-tissue in vivo imaging. However, it is challenging to synthesize NIR-II probes with high quantum yields (QYs), good biocompatibility, satisfactory pharmacokinetics, and tunable biological properties. Conventional long-wavelength probes, such as inorganic probes (which often contain heavy metal atoms in their scaffolds) and organic dyes […]