Flavivirus genome recoding by codon optimisation confers genetically stable in vivo attenuation in both mice and mosquitoes

Authors: Wei-Xin Chin, Hao Yuin Kong, Isabelle Xin Yu Zhu, Zi Yun Teo, Regina Faruk, Regina Ching Hua Lee, Si Xian Ho, Zhen Qin Aw, Bowen Yi, Xin Jun Hou, Antson Kiat Yee Tan, Thinesshwary Yogarajah, Roland G Huber, Yu Cai, Yue Wan, Justin Jang Hann Chu

Journal: PLoS pathogens. 2023 Oct 26;19(10):e1011753.

DOI: 10.1371/journal.ppat.1011753

 

Notable Achievements

Awards & Appointments

NUS Medicine Infectious Diseases researcher Dr Mo Yin receives L’Oréal-UNESCO For Women in Science Award 2025

NUS Medicine Infectious Diseases researcher Dr Mo Yin receives L’Oréal-UNESCO …

Awards & Appointments

National Medical Research Council Open Fund – Individual Research Grant 2025

Congratulations to our NUSMed Infectious Diseases TRP PI A/Prof. Chu …

Awards & Appointments

National Medical Research Council Talent Award Winners 2025

Congratulations to our NUSMed Infectious Diseases TRP PIs, A/Prof Catherine …

Secondary Members

David ALLEN

Associate Professor​ (Medicine)​ ​

Sophia ARCHULETA

Associate Professor (Medicine)

Yann BOUCHER

Associate Professor (SPH)​

Louis CHAI

Associate Professor​ (Medicine)​

Kaiwen CHEN

Assistant Professor (Micro & Immuno)

CHN'G Jun Hong

Senior Lecturer (Micro & Immuno)

 

LOK Shee Mei

 Professor (Duke-NUS)

Hannah CLAPHAM

Assistant Professor (SPH)

Dale FISHER​

Professor​ (Medicine)​

KOH Cho Yeow

Associate Professor (Medicine)

Raymond LIN

Associate Professor​ (NPHL-NCID)​

LUO Min

Assistant Professor (DBS)

Benoit MALLERET

Assistant Professor (Micro & Immuno)

Matthew TAY

Adjunct Assistant Professor (Biochemistry)

Kevin TAN

Associate Professor​ (Micro & Immuno)​

Adjunct Members

Guillaume CARISSIMO

Assistant Professor​ (A*STAR ID Labs)

Yin Xiang SETOH​

Assistant Professor​ (EHI)​

Marco VIGNUZZI

Associate Professor 
(A*STAR ID Labs)

Primary Members

Sylvie ALONSO​

Associate Professor

John CHEN​

Associate Professor

Vincent CHOW​

Associate Professor​

Justin CHU

Associate Professor​

GAN Yunn Hwen

Associate Professor

HSU Li Yang​

 Professor

Catherine ONG​

Associate Professor

David PATERSON

Professor

Nick PATON​

Professor​

QU Kun

Assistant Professor

SHAM​ Lok To

Associate Professor​

Paul A. TAMBYAH

Professor

TAN Chee Wah

Research Assistant Professor

TAN Yee Joo​

Associate Professor​

Thai TRAN​

Associate Professor​

NAGARAJAN Niranjan

Associate Professor

ZHONG Youjia

Assistant Professor

CHNG Shu Sin

Associate Professor​ (Chemistry)​

MO Yin

Consultant (Medicine) 

Yassine CHERRAK

Assistant Professor

Cheryl LEE Qi En

Assistant Professor ?

CHNG Shu Sin

Associate Professor​ (Chemistry)​

MO Yin

Consultant (Medicine) 

WANG De Yun​

Professor​

TAN Yee Joo​

Associate Professor​