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High Profile Publications

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High Profile Publications

Adjunctive pascolizumab in rifampicin-susceptible pulmonary tuberculosis: proof-of-concept, partially-randomised, double-blind, placebo-controlled, dose-escalation trial

Authors: Nicholas I Paton, Meera Gurumurthy, Qingshu Lu, Francesca Leek, Philip Kwan, Hiromi W L Koh, James Molton, Lala...
High Profile Publications

Short-chain fatty acids of various lengths differentially inhibit Klebsiella pneumoniae and Enterobacteriaceae species

Authors: Kai Chirng Chang, Niranjan Nagarajan, Yunn-Hwen Gan Journal: mSphere. 2024 Feb 28;9(2):e0078123. DOI: 10.1128/m...
High Profile Publications

Updated epithelial barrier dysfunction in chronic rhinosinusitis: Targeting pathophysiology and treatment response of tight junctions

Authors: Zhi-Qun Huang, Jing Liu, Li-Ying Sun, Hsiao Hui Ong, Jing Ye, Yu Xu, De-Yun Wang Journal: Allergy. 2024 Feb 19....
High Profile Publications

Attenuation of neurovirulence of chikungunya virus by a single amino acid mutation in viral E2 envelope protein

Authors: Huixin Chen, Patchara Phuektes, Li Sze Yeo, Yi Hao Wong, Regina Ching Hua Lee, Bowen Yi, Xinjun Hou, Sen Liu, Y...
High Profile Publications

Differential effects of microRNAs miR-21, miR-99 and miR-145 on lung regeneration and inflammation during recovery from influenza pneumonia

Authors: Joe Wee Jian Ong, Kai Sen Tan, Joseph Jing Xian Lee, Ju Ee Seet, Hyung Won Choi, Siok Ghee Ler, Jayantha Gunara...
High Profile Publications

Expanding the anti-flaviviral arsenal: Discovery of a baicalein-derived Compound with potent activity against DENV and ZIKV

Authors: Geraldine Nadya Putri, Chandra Sekhar Gudla, Mayas Singh, Chin Huan Ng, Fakhriedzwan Fitri Haji Idris, Yukei Oo...
High Profile Publications

Hypoxia-inducible factor 1α activates the NLRP3 inflammasome to regulate epithelial differentiation in chronic rhinosinusitis

Authors: Bing Zhong, Silu Sun, Kai Sen Tan, Hsiao Hui Ong, Jintao Du, Feng Liu, Yafeng Liu, Shixi Liu, Luo Ba, Jing Li, ...
High Profile Publications

Potential relevance of salivary legumain for the clinical diagnostic of hand, foot, and mouth disease

Authors: HYong Wah Tan, Fiona Mei Shan Teo, Siok Ghee Ler, Asfa Alli-Shaik, Min Nyo, Chia Yin Chong, Natalie Woon Hui Ta...
High Profile Publications

SPACEL: deep learning-based characterization of spatial transcriptome architectures

Authors: Hao Xu, Shuyan Wang, Minghao Fang, Songwen Luo, Chunpeng Chen, Siyuan Wan, Rirui Wang, Meifang Tang, Tian Xue, ...